Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gung Lee"'
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte
Externí odkaz:
https://doaj.org/article/c719b3a3e9594fb9a44b17d3954cfdae
Autor:
Jinuk Kong, Yul Ji, Yong Geun Jeon, Ji Seul Han, Kyung Hee Han, Jung Hyun Lee, Gung Lee, Hagoon Jang, Sung Sik Choe, Myriam Baes, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Lipid droplets are organelles that regulate lipid metabolism but if organellar contacts play a role during lipolysis is unclear. Here, the authors show that peroxisomes and peroxisomal protein PEX5 play pivotal roles in the spatial and temporal regul
Externí odkaz:
https://doaj.org/article/ca6fe38e928249d98547a91aacc29c51
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S23, Pp 1-12 (2019)
Abstract Background The main research topic in this paper is how to compare multiple biological experiments using transcriptome data, where each experiment is measured and designed to compare control and treated samples. Comparison of multiple biolog
Externí odkaz:
https://doaj.org/article/d9911c6684f34426a662d1ce8255bf35
Autor:
Hagoon Jang, Gha Young Lee, Christopher P. Selby, Gung Lee, Yong Geun Jeon, Jae Ho Lee, Kenneth King Yip Cheng, Paul Titchenell, Morris J. Birnbaum, Aimin Xu, Aziz Sancar, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic gluc
Externí odkaz:
https://doaj.org/article/8d7c5bde883440f7b735e96aacbc548c
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49993 (2012)
Accumulating evidence suggests that the circadian clock is closely associated with metabolic regulation. However, whether an impaired circadian clock is a direct cause of metabolic dysregulation such as body weight gain is not clearly understood. In
Externí odkaz:
https://doaj.org/article/0a54f620b3a246d894c36d1708a1649e
Publikováno v:
Nature Metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef68419fb5d0bbac03476afb9918727b
https://doi.org/10.1038/s42255-023-00786-y
https://doi.org/10.1038/s42255-023-00786-y
Autor:
Ye Young Kim, Hagoon Jang, Gung Lee, Yong Geun Jeon, Jee Hyung Sohn, Ji Seul Han, Won Taek Lee, Jeu Park, Jin Young Huh, Hahn Nahmgoong, Sang Mun Han, Jeesoo Kim, Minwoo Pak, Sun Kim, Jong-Seo Kim, Jae Bum Kim
Publikováno v:
Diabetes. 71:1373-1387
Excessive hepatic glucose production (HGP) is a key factor promoting hyperglycemia in diabetes. Hepatic cryptochrome 1 (CRY1) plays an important role in maintaining glucose homeostasis by suppressing forkhead box protein O1 (FOXO1)-mediated HGP. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2b3231822891cb3d656ff01634366
https://doi.org/10.2337/db21-0649
https://doi.org/10.2337/db21-0649
Autor:
Gung Lee
Publikováno v:
Molecules and Cells. 45:531-533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2364387bbdcc5b615b20ad63211a7eea
https://doi.org/10.14348/molcells.2022.0084
https://doi.org/10.14348/molcells.2022.0084
Autor:
Jeu Park, Do Hoon Lee, Seokjin Ham, Jiyoung Oh, Jung-Ran Noh, Yun Kyung Lee, Yoon Jeong Park, Gung Lee, Sang Mun Han, Ji Seul Han, Ye Young Kim, Yong Geun Jeon, Han Nahmgoong, Kyung Cheul Shin, Sung Min Kim, Sung Hee Choi, Chul-Ho Lee, Jiyoung Park, Tae Young Roh, Sun Kim, Jae Bum Kim
Publikováno v:
Nature metabolism. 4(7)
DNA methylation is a crucial epigenetic modification in the establishment of cell-type-specific characteristics. However, how DNA methylation is selectively reprogrammed at adipocyte-specific loci during adipogenesis remains unclear. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfaff0d8fceb9a2b779488f4afe2dce
https://pubmed.ncbi.nlm.nih.gov/35788760
https://pubmed.ncbi.nlm.nih.gov/35788760
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature communications. 13(1)
Thermogenic adipocytes generate heat to maintain body temperature against hypothermia in response to cold. Although tight regulation of thermogenesis is required to prevent energy sources depletion, the molecular details that tune thermogenesis are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d6938eb922a3d1a71c1314386b6d63
https://pubmed.ncbi.nlm.nih.gov/35672324
https://pubmed.ncbi.nlm.nih.gov/35672324