Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gunes Bozkurt"'
Autor:
Sharvan Sehrawat, Oktay Kirak, Paul-Albert Koenig, Marisa K. Isaacson, Sofia Marques, Gunes Bozkurt, J. Pedro Simas, Rudolph Jaenisch, Hidde L. Ploegh
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 461-471 (2012)
To study the CD8+ T cell response against a mouse γ-herpes virus, we generated Kb-MHV-68-ORF8604–612RAG−/− CD8+ T cell receptor transnuclear (TN) mice as a source of virus-specific CD8+ T cells. Kb-ORF8-Tet+ CD8+ T cells, expanded in the cours
Externí odkaz:
https://doaj.org/article/50a45be07d2f423bbb0a62d340d861f1
Publikováno v:
EMBO reports. 20
The murine cytomegalovirus protein M45 protects infected mouse cells from necroptotic death and, when heterologously expressed, can protect human cells from necroptosis induced by tumour necrosis factor receptor (TNFR) activation. Here, we show that
Publikováno v:
Science Trends.
Autor:
Hao Wu, Ségolène Laage, Miguel Mompeán, Ansgar B. Siemer, Jixi Li, Ann E. McDermott, Gunes Bozkurt, Wenbo Li
The RIPK1-RIPK3 necrosome is an amyloid signaling complex that initiates TNF-induced necroptosis, serving in human immune defense, cancer and neurodegenerative diseases. RIPK1 and RIPK3 associate through their RIP homotypic interaction motifs with co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bb8042b94eea20684bc6ddb4667c0f
https://europepmc.org/articles/PMC6002806/
https://europepmc.org/articles/PMC6002806/
Publikováno v:
Scientific Reports
Scientific reports, vol 8, iss 1
Scientific reports, vol 8, iss 1
Glycosylphosphatidylinositol (GPI) transamidase (GPIT), the enzyme that attaches GPI anchors to proteins as they enter the lumen of the endoplasmic reticulum, is a membrane-bound hetero-pentameric complex consisting of Gpi8, Gpi16, Gaa1, Gpi17 and Ga
Autor:
Guillaume Lamour, Jörg Gsponer, Patrick Chan, Hao Wu, Gunes Bozkurt, Thibault Mayor, Roy Nassar, Hongbin Li, Jennifer M. Bui, Jixi Li, Calvin K. Yip
Amyloids are fibrillar nanostructures of proteins that are assembled in several physiological processes in human cells (e.g., hormone storage) but also during the course of infectious (prion) and noninfectious (nonprion) diseases such as Creutzfeldt-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee279007cf836462faa157e251fe8ada
https://europepmc.org/articles/PMC5340157/
https://europepmc.org/articles/PMC5340157/
Autor:
Christopher S. Theile, Lenka Kundrat, Gunes Bozkurt, Annet E M Blom, Hidde L. Ploegh, Carla P. Guimaraes, Martin D. Witte
Publikováno v:
Nature protocols, 8(9), 1787-1799. Nature Publishing Group
Methods for site-specific modification of proteins should be quantitative and versatile with respect to the nature and size of the biological or chemical targets involved. They should require minimal modification of the target, and the underlying rea
Publikováno v:
Proceedings of the National Academy of Sciences. 107:11295-11300
Flagella are the bacterial organelles of motility and can play important roles in pathogenesis. Flagella biosynthesis requires the coordinated export of huge protein amounts from the cytosol to the nascent flagellar structure at the cell surface and
Autor:
Goran Stjepanovic, Stefan Amlacher, Irmgard Sinning, Gert Bange, Fabio Vilardi, Vincenzo Favaloro, Karsten Rippe, Bernhard Dobberstein, Ed Hurt, Klemens Wild, Gunes Bozkurt
Publikováno v:
Proceedings of the National Academy of Sciences. 106:21131-21136
Tail-anchored (TA) membrane proteins are involved in a variety of important cellular functions, including membrane fusion, protein translocation, and apoptosis. The ATPase Get3 (Asna1, TRC40) was identified recently as the endoplasmic reticulum targe
Autor:
Nancy F. Ramia, Jing Huang, Neal S. Silverman, Yanfang Shen, Johanna Napetschnig, Jixi Li, Hao Wu, Gunes Bozkurt, Monique Gangloff, Himani Nailwal, Francis Ka-Ming Chan, Anni Kleino
Publikováno v:
Immunity. 47:635-647.e6
Summary In the Drosophila immune response, bacterial derived diaminopimelic acid-type peptidoglycan binds the receptors PGRP-LC and PGRP-LE, which through interaction with the adaptor protein Imd leads to activation of the NF-κB homolog Relish and r