Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Guneet Walia"'
Autor:
Sarah Barger, Sean D. Sullivan, Ari Bell-Brown, Brad Bott, Anne Marie Ciccarella, John Golenski, Mark Gorman, Judy Johnson, Karma Kreizenbeck, Florence Kurttila, Ginny Mason, Jamie Myers, Carole Seigel, James L. Wade, Guneet Walia, Kate Watabayashi, Gary H. Lyman, Scott D. Ramsey
Publikováno v:
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background The Fred Hutchinson Cancer Research Center has engaged an External Stakeholder Advisory Group (ESAG) in the planning and implementation of the TrACER Study (S1415CD), a five-year pragmatic clinical trial assessing the effectivenes
Externí odkaz:
https://doaj.org/article/f17e98e5d91a4c84a1c6ccf2e3ea63c4
Autor:
Guneet Walia, Avadhesha Surolia
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21390 (2011)
Being vastly different from the human counterpart, we suggest that the last enzyme of the Mycobacterium tuberculosis Coenzyme A biosynthetic pathway, dephosphocoenzyme A kinase (CoaE) could be a good anti-tubercular target. Here we describe detailed
Externí odkaz:
https://doaj.org/article/5a02e3e06578451cb705b76095583f83
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15228 (2011)
Dephosphocoenzyme A kinase performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A, catalyzing the last step of coenzyme A biosynthesis. This enzyme belongs to the P-loop-containing NTP hydrolase superfamily, all members of which poss
Externí odkaz:
https://doaj.org/article/246a2b7526db4992bbbe3aa91f3bc23a
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7645 (2009)
BACKGROUND:Targeting the biosynthetic pathway of Coenzyme A (CoA) for drug development will compromise multiple cellular functions of the tubercular pathogen simultaneously. Structural divergence in the organization of the penultimate and final enzym
Externí odkaz:
https://doaj.org/article/847553f59e8b44ff9a8afad28eaa6542
Autor:
Ari Bell-Brown, Kate Watabayashi, Karma Kreizenbeck, Scott D Ramsey, Aasthaa Bansal, William E Barlow, Gary H Lyman, Dawn L Hershman, Anne Marie Mercurio, Barbara Segarra-Vazquez, Florence Kurttila, Jamie S Myers, John D Golenski, Judy Johnson, Robert L Erwin, Guneet Walia, Jeffrey Crawford, Sean D Sullivan
Publikováno v:
Journal of comparative effectiveness research. 11(18)
Aim: Stakeholder engagement is central to comparative effectiveness research yet there are gaps in definitions of success. We used a framework developed by Lavallee et al. defining effective engagement criteria to evaluate stakeholder engagement duri
Autor:
Divya Ahuja Parikh, Bonnie J. Addario, Janet Freeman-Daily, Manali I. Patel, Guneet Walia, Lisa Goldman, Merel Hennink, Tori Tomalia, Lysa Buonanno
Publikováno v:
JCO Oncol Pract
PURPOSE: The discovery of driver oncogenes, such as ROS1, has led to the development of targeted therapies. Despite clinical advancements, gaps remain in our understanding of characteristics of patients with ROS1-positive ( ROS1+) cancers. The purpos
Autor:
M. Cabili, E. Williams, S. Lee, M. Lu, Roy S. Herbst, A. Bourla, Guneet Walia, Lee S. Schwartzberg, Katja Schulze, Anne C. Chiang, N. Mirkovic, B. Fang, E. Santos, R. Dicecca
Publikováno v:
Journal of Thoracic Oncology. 16:S316-S317
Autor:
Ethan Sokol, Dexter X. Jin, Zoe June Assaf, Smruthy Sivakumar, Svetlana Lyalina, Guneet Walia, Sally E. Trabucco, Sophia Maund
Publikováno v:
Clinical Cancer Research. 26:A17-A17
Comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) provides an opportunity to noninvasively monitor a patient’s tumor burden via liquid biopsy. Liquid biopsies can assess a patient’s mutational landscape through time and provi
Autor:
Lee S. Schwartzberg, Sarah Gaffey, Robert J. Green, Anne C. Chiang, Sophia Maund, Ariel B. Bourla, M. Lu, Moran N Cabili, Roy S. Herbst, Michelle Y. Doral, Guneet Walia, Eric C. Santos, Katja Schulze
Publikováno v:
Journal of Clinical Oncology. 38:TPS2087-TPS2087
TPS2087 Background: Making personalized diagnostics and treatments a reality for every cancer patient necessitates comprehensively capturing the patient journey. Real-world data has shown promise for the future of clinical research and advancing prec
Autor:
Scott D. Ramsey, Carole Seigel, Guneet Walia, Gary H. Lyman, Ari Bell-Brown, Sarah Barger, Ginny Mason, John Golenski, Judy Johnson, Karma L. Kreizenbeck, Jamie S. Myers, Brad Bott, Mark Gorman, James L. Wade, Kate Watabayashi, Florence Kurttila, Anne Marie Ciccarella, Sean D. Sullivan
Publikováno v:
BMC Medical Research Methodology
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-7 (2019)
Background The Fred Hutchinson Cancer Research Center has engaged an External Stakeholder Advisory Group (ESAG) in the planning and implementation of the TrACER Study (S1415CD), a five-year pragmatic clinical trial assessing the effectiveness of a gu