Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gunars Osis"'
Publikováno v:
Clin J Am Soc Nephrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84224d7092ff56bb017f496a59505632
https://europepmc.org/articles/PMC8823938/
https://europepmc.org/articles/PMC8823938/
Autor:
Anupam Agarwal, Daria Barwinska, Tarek M. El-Achkar, Malgorzata M. Kamocka, Shehnaz Khan, Grace Whipple, Amie M. Traylor, Abolfazl Zarjou, Anna A. Zmijewska, Laurence M. Black, Gunars Osis, Seth Winfree, Elisa R Farrell, Daryll R Spangler, Stephanie K Esman, Subhashini Bolisetty
Publikováno v:
Am J Physiol Renal Physiol
Expansion of renal lymphatic networks, or lymphangiogenesis (LA), is well recognized during development and is now being implicated in kidney diseases. Although LA is associated with multiple pathological conditions, very little is known about its ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83d4fb76b13a056bb5c64f0c9f67968
https://europepmc.org/articles/PMC8714977/
https://europepmc.org/articles/PMC8714977/
Autor:
Christopher Yanucil, Dominik Kentrup, Isaac Campos, Brian Czaya, Kylie Heitman, David Westbrook, Gunars Osis, Alexander Grabner, Adam R. Wende, Julian Vallejo, Michael J. Wacker, Jose Alberto Navarro-Garcia, Gema Ruiz-Hurtado, Fuming Zhang, Yuefan Song, Robert J. Linhardt, Kenneth White, Michael S. Kapiloff, Christian Faul
Publikováno v:
Kidney international. 102(2)
Fibroblast growth factor (FGF) 23 is a phosphate-regulating hormone that is elevated in patients with chronic kidney disease and associated with cardiovascular mortality. Experimental studies showed that elevated FGF23 levels induce cardiac hypertrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56c67ca88fc190df57c2ab4869d12b2
https://pubmed.ncbi.nlm.nih.gov/35870810
https://pubmed.ncbi.nlm.nih.gov/35870810
Autor:
Lijuan Fang, Jill W. Verlander, Gunars Osis, I. David Weiner, Hyun-Wook Lee, Autumn N. Harris, Kierstin L. Webster
Publikováno v:
American Journal of Physiology-Renal Physiology. 315:F211-F222
Renal ammonia metabolism has a major role in the maintenance of acid-base homeostasis. Sex differences are well recognized as an important biological variable in many aspects of renal function, including fluid and electrolyte metabolism. However, sex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326e65ba7096f2bd6a12c2896914ee0b
https://doi.org/10.1152/ajprenal.00084.2018
https://doi.org/10.1152/ajprenal.00084.2018
Autor:
Anupam Agarwal, Gunars Osis
Publikováno v:
Am J Physiol Renal Physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8821298dc0fa59062ff79cb169dc11
https://doi.org/10.1152/ajprenal.00282.2021
https://doi.org/10.1152/ajprenal.00282.2021
Autor:
Chao Chen, Autumn N. Harris, Kierstin L. Webster, Michael F. Romero, Hyun-Wook Lee, Lijuan Fang, Matthew E. Merritt, Ram B. Khattri, I. David Weiner, Gunars Osis, Jill W. Verlander
Publikováno v:
Am J Physiol Renal Physiol
Citrate is critical for acid-base homeostasis and to prevent calcium nephrolithiasis. Both metabolic acidosis and hypokalemia decrease citrate excretion and increase expression of Na+-dicarboxylate cotransporter 1 (NaDC1; SLC13A2), the primary protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351e212a240eb524263297ba08981cd4
https://pubmed.ncbi.nlm.nih.gov/31188034
https://pubmed.ncbi.nlm.nih.gov/31188034
Autor:
Wouter H. Lamers, Hyun-Wook Lee, Farrukh A. Chaudhry, I. David Weiner, Jill W. Verlander, Gunars Osis, Mary E. Handlogten
Publikováno v:
American journal of physiology. Renal physiology, 310(11), F1229-F1242. American Physiological Society
Glutamine synthetase (GS) catalyzes the recycling of NH4+with glutamate to form glutamine. GS is highly expressed in the renal proximal tubule (PT), suggesting ammonia recycling via GS could decrease net ammoniagenesis and thereby limit ammonia avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6390ae5670e5d4d68faa1504dbcdd74d
https://doi.org/10.1152/ajprenal.00547.2015
https://doi.org/10.1152/ajprenal.00547.2015
Autor:
Michael F. Romero, Lijuan Fang, I. David Weiner, Hyun-Wook Lee, Mary E. Handlogten, Jill W. Verlander, Gunars Osis, Autumn N. Harris
Renal ammonia metabolism is the primary mechanism through which the kidneys maintain acid-base homeostasis, but the molecular mechanisms regulating renal ammonia generation are unclear. In these studies, we evaluated the role of the proximal tubule b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2f32958dcb289571157462a00200fe
https://europepmc.org/articles/PMC5875958/
https://europepmc.org/articles/PMC5875958/
Publikováno v:
American Journal of Physiology-Renal Physiology. 308:F1463-F1473
Dietary protein restriction has multiple benefits in kidney disease. Because protein intake is a major determinant of endogenous acid production, it is important that net acid excretion change in parallel during protein restriction. Ammonia is the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dd8ce179f82ad97ea52f07e9acd716
https://doi.org/10.1152/ajprenal.00077.2015
https://doi.org/10.1152/ajprenal.00077.2015
Autor:
Jill W. Verlander, William L. Clapp, Gunars Osis, Florence M. Whitehill, Mary E. Handlogten, Hyun-Wook Lee, Ki Hwan Han, I. David Weiner, Byron P. Croker
Publikováno v:
American Journal of Physiology-Renal Physiology. 304:F972-F981
The ammonia transporter family member, Rh B Glycoprotein (RhBG/Rhbg), is essential for ammonia transport by the rodent kidney, but in the human kidney mRNA but not protein expression has been reported. Because ammonia transport is fundamental for aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3c671e328048fb1ea8c36173dc99c4
https://doi.org/10.1152/ajprenal.00550.2012
https://doi.org/10.1152/ajprenal.00550.2012