Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Gunapala, Shetty"'
Autor:
Enrique Sosa, Di Chen, Ernesto J. Rojas, Jon D. Hennebold, Karen A. Peters, Zhuang Wu, Truong N. Lam, Jennifer M. Mitchell, Meena Sukhwani, Ramesh C. Tailor, Marvin L. Meistrich, Kyle E. Orwig, Gunapala Shetty, Amander T. Clark
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus mac
Externí odkaz:
https://doaj.org/article/364bc6a1087149ce821ef0255a15a53c
Autor:
Jennifer M. Mitchell, Gunapala Shetty, Marvin L. Meistrich, Thien Trong Phan, Ramesh C. Tailor, Carol B. Hanna, Kyle E. Orwig, Truong Nguyen Anh Lam, Jie Zhang, Karen A. Peters, Amander T. Clark, Maria Cecilia T. Penedo
Publikováno v:
Andrology
Andrology, vol 9, iss 5
Andrology, vol 9, iss 5
BackgroundCancer treatment of prepubertal patients impacts future fertility due to the abolition of spermatogonial stem cells (SSCs). In macaques, spermatogenesis could be regenerated by intratesticular transplantation of SSCs, but no studies have in
Publikováno v:
Journal of the American Veterinary Medical Association. 258:161-164
Autor:
C A Rezende-Melo, Martin M. Matzuk, G M Buchold, Marvin L. Meistrich, Shosei Yoshida, Hélio Chiarini-Garcia, Gunapala Shetty, Kenshiro Hara, F. R. C. L. Almeida, A L Drumond-Bock, Andre L. Caldeira-Brant
Publikováno v:
Reproduction. 160:205-215
The existence of cytoplasmic passages between germ cells and their potential function in the control of the spermatogenic process has long been an intriguing question. Evidence of the important role of such structures, known as intercellular bridges
Autor:
Thien Trong Phan, Kyle E. Orwig, Carol B. Hanna, Ramesh C. Tailor, Jie Zhang, Karen A. Peters, Jennifer M. Mitchell, Gunapala Shetty, Marvin L. Meistrich, Zhuang Wu, Jennifer M. Meyer, Truong Nguyen Anh Lam, Lorraine R Hill, Maria Cecilia T. Penedo
Publikováno v:
Andrology
Background In male pre-pubertal cancer patients, radiation and chemotherapy impact future fertility by eradication of spermatogonial stem cells (SSCs). In macaques, spermatogenesis could be regenerated by intratesticular transplantation of SSCs, but
Autor:
Reham Waheeb, Marvin L. Meistrich, Thomas X. Garcia, Gunapala Shetty, Marie Claude Hofmann, Pooja Gandhi, Parag Parekh, Vivek Jain
Publikováno v:
The FASEB Journal. 33:8423-8435
Cytochrome P450 family 26 subfamily B member 1 (CYP26B1) regulates the concentration of all-trans retinoic acid (RA) and plays a key role in germ cell differentiation by controlling local distribution of RA. The mechanisms regulating Cyp26b1 expressi
Autor:
Gunapala Shetty, Victoria H. J. Roberts, Marvin L. Meistrich, Hanna Valli-Pulaski, Adetunji P. Fayomi, Cathy Ramsey, Carol B. Hanna, Jon D. Hennebold, Ina Dobrinski, Nicola Robertson, Meena Sukhwani, Karen A. Peters, Kyle E. Orwig, Lisa A Houser
Publikováno v:
Science. 363:1314-1319
Preserving male fertility Before chemotherapy or radiation treatment, sperm from adult men can be cryopreserved for future use. However, this is not possible for prepubertal boys. Fayomi et al. grafted cryopreserved testicular tissue from castrated p
Autor:
Paul B Comish, Ana Luiza Drumond, Hazel L Kinnell, Richard A Anderson, Angabin Matin, Marvin L Meistrich, Gunapala Shetty
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93311 (2014)
Exposure to radiation during fetal development induces testicular germ cell tumors (TGCT) and reduces spermatogenesis in mice. However, whether DNA damaging chemotherapeutic agents elicit these effects in mice remains unclear. Among such agents, cycl
Externí odkaz:
https://doaj.org/article/46f27dca5a4e46849f8299f3377c0081
Autor:
Thien Trong Phan, Marvin L. Meistrich, Truong Nguyen Anh Lam, Zhuang Wu, Gunapala Shetty, Kyle E. Orwig
Publikováno v:
Andrology. 7:257-265
Background Cytotoxic cancer treatments, such as irradiation, can cause permanent sterility in male mammals owing to the loss of spermatogonial stem cells. In animal models, spermatogenesis could be restored from transplanted spermatogonial stem cells
Autor:
Marvin L. Meistrich, Gunapala Shetty
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1069-1070 (2015)
In this issue of Cell Reports, DeFalco et al. (2015) characterize a novel macrophage population associated with the peritubular lamina of mouse testes. These macrophages may create a niche not for the self-renewal of stem cells but rather the inducti
Externí odkaz:
https://doaj.org/article/2ab80014e30447fd871d2653ef988399