Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gun-sik Cho"'
Autor:
Gun-Sik Cho, Dong I. Lee, Emmanouil Tampakakis, Sean Murphy, Peter Andersen, Hideki Uosaki, Stephen Chelko, Khalid Chakir, Ingie Hong, Kinya Seo, Huei-Sheng Vincent Chen, Xiongwen Chen, Cristina Basso, Steven R. Houser, Gordon F. Tomaselli, Brian O’Rourke, Daniel P. Judge, David A. Kass, Chulan Kwon
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 571-582 (2017)
Summary: Pluripotent stem cells (PSCs) offer unprecedented opportunities for disease modeling and personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and remain immature in a dish. This has emerged as a major obstacle
Externí odkaz:
https://doaj.org/article/04ac548333594c669d794d791d77417d
Autor:
Lincoln T Shenje, Peter Andersen, Hideki Uosaki, Laviel Fernandez, Peter P Rainer, Gun-sik Cho, Dong-ik Lee, Weimin Zhong, Richard P Harvey, David A Kass, Chulan Kwon
Publikováno v:
eLife, Vol 3 (2014)
Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient ce
Externí odkaz:
https://doaj.org/article/28fce4bb0d45423fb9e788b539632d97
Publikováno v:
Nature Protocols. 12:2097-2109
Pluripotent stem cells (PSCs), including induced PSCs, hold great potential for personalized disease modeling, drug testing, and cell-based therapeutics. However, cells differentiated from PSCs remain immature in a dish, and this has emerged as a maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36fc93af4b0238730b87862ff7bc3f
https://doi.org/10.1038/nprot.2017.089
https://doi.org/10.1038/nprot.2017.089
Publikováno v:
Developmental Biology. 421:183-193
During early embryogenesis, FGF signals regulate the antero-posterior (AP) patterning of the neural plate by promoting posterior cell fates. In particular, BMP signal-mediated attenuation of FGF pathway plays a critical role in the determination of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22de2b57a2f64747b2f6228ccc9493d
https://doi.org/10.1016/j.ydbio.2016.11.020
https://doi.org/10.1016/j.ydbio.2016.11.020
Publikováno v:
eNeuro
Visual Abstract
The human cerebral cortex is a complex structure with tightly interconnected excitatory and inhibitory neuronal networks. In order to study human cortical function, we recently developed a method to generate cortical neurons from
The human cerebral cortex is a complex structure with tightly interconnected excitatory and inhibitory neuronal networks. In order to study human cortical function, we recently developed a method to generate cortical neurons from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af5ff12de9f3ee9c64674bf335248fe
http://europepmc.org/articles/PMC6709226
http://europepmc.org/articles/PMC6709226
Autor:
Choongseong Han, Hyo Sung Jung, Jong-Hoon Kim, Jong Seung Kim, Ji-Young Park, Gyunggyu Lee, Han-Jin Park, Gun Sik Cho, Jiyou Han, Hyojin Kim
Publikováno v:
Biomaterials. 222
Hepatocytes derived from human pluripotent stem cells (hPSCs) are promising candidates for cell therapy and drug discovery. However, it remains challenging to efficiently purify hepatocytes from undesired cell types after differentiation and to accur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02aacb2fc6ee768bc43a9896bb725a9
https://pubmed.ncbi.nlm.nih.gov/31450160
https://pubmed.ncbi.nlm.nih.gov/31450160
Autor:
Xinzhong Dong, Min-Jeong Kim, Chulan Kwon, Richard L. Huganir, Emmanouil Tampakakis, Gabsang Lee, Leslie Tung, Yong Jun Kim, Yohan Oh, Gun-Sik Cho, Zhe Li, Ingie Hong, Renjun Zhu
Publikováno v:
ResearcherID
Neurons derived from human pluripotent stem cells (hPSCs) are powerful tools for studying human neural development and diseases. Robust functional coupling of hPSC-derived neurons with target tissues in vitro is essential for modeling intercellular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a1d517c5e8495df538b97681217df3
https://doi.org/10.1016/j.stem.2016.05.002
https://doi.org/10.1016/j.stem.2016.05.002
Autor:
Wonhee Han, Jin-Kwan Han, Sanguk Kim, Seong-Moon Cheong, Gun-Sik Cho, Jae-Seong Yang, Hyeyoon Lee, Youngmu Koo, Saet-Byeol Jo
Publikováno v:
Development.
Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis. However, whether antagonism of Wnt signaling necessary for vertebrate head formation can be achieved through regulation of Dsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364c85b0743aa49232dcd787dca18dc4
https://doi.org/10.1242/dev.143107
https://doi.org/10.1242/dev.143107
Autor:
Choongseong Han, Hee Kyung Park, Jong-Hoon Kim, Dong Hun Woo, Gun Sik Cho, Dong-Kyu Kim, Dong Hyuk Park
Publikováno v:
Tissue engineering and regenerative medicine. 14(6)
Liver failure is one of the main risks of death worldwide, and it originates from repetitive injuries and inflammations of liver tissues, which finally leads to the liver cirrhosis or cancer. Currently, liver transplantation is the only effective tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31fbf7f3826d10d02718fc90535286d
https://pubmed.ncbi.nlm.nih.gov/30603518
https://pubmed.ncbi.nlm.nih.gov/30603518
Autor:
Emmanouil Tampakakis, Steven R. Houser, Chulan Kwon, Khalid Chakir, Sean Murphy, Gordon F. Tomaselli, Cristina Basso, Kinya Seo, Xiongwen Chen, Hideki Uosaki, Brian O'Rourke, Peter Andersen, Ingie Hong, Huei Sheng Vincent Chen, Dong I. Lee, David A. Kass, Gun Sik Cho, Stephen P. Chelko, Daniel P. Judge
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 571-582 (2017)
Summary: Pluripotent stem cells (PSCs) offer unprecedented opportunities for disease modeling and personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and remain immature in a dish. This has emerged as a major obstacle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd57fb33b45d534ffadd36fefd5c694f
https://europepmc.org/articles/PMC5232412/
https://europepmc.org/articles/PMC5232412/
