Melatonin induces fat browning by transdifferentiation of white adipocytes and de novo differentiation of mesenchymal stem cells

Autor: Diego Salagre, Meriem Chayah, Antonio Molina-Carballo, María-Jesús Oliveras-López, Antonio Munoz-Hoyos, Miguel Navarro-Alarcón, Gumersindo Fernández-Vázquez, Ahmad Agil

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname

This research was partially supported by grant SAF2016-79794R from the Ministerio de Ciencia e Innovacion (Spain), European Regional Development Fund (ERDF), University of Granada and FEDER Funds grant number B-CTS-102-UGR20. The authors thank Antoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f347a25e49e5adc3b29615ad298387d4
https://doi.org/10.1039/d1fo04360a

Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats

Autor: Gumersindo Fernández-Vázquez, Russel J. Reiter, Mohamed Tassi, J.M.R. Ferrer, Ahmad Agil, Miguel Navarro-Alarcón, Lucia Visiedo, Meriem Chayah

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Clinical Medicine, Vol 9, Iss 2916, p 2916 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Journal of Clinical Medicine
Volume 9
Issue 9

Obesity and associated diabetes (diabesity) impair kidney mitochondrial dynamics by augmenting fission and diminishing fusion, which results in mitochondrial and renal dysfunction. Based on available evidence, the antioxidant activities of melatonin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f6a5d36c451958a8ea2114cf97e342
https://hdl.handle.net/10668/3850

Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats

Autor: Ahmad Agil, Gumersindo Fernández-Vázquez, Russel J. Reiter, Aroa Jiménez-Aranda, María Mohammad A-Serrano

Publikováno v: Journal of Pineal Research. 57:103-109

Mitochondrial dysfunction in adipose tissue may contribute to obesity-related metabolic derangements such as type 2 diabetes mellitus (T2DM). Because mitochondria are a target for melatonin action, the goal of this study was to investigate the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6495dc15149fba51278965f1093d5039
https://doi.org/10.1111/jpi.12147

Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats

Autor: Gumersindo Fernández-Vázquez, Rosario Ruiz, Isaac Rosado, Adriana Figueroa, Ahmad Agil, Nourahouda Zen

Publikováno v: Journal of Pineal Research. 52:203-210

The aim of this study was to investigate the effects of melatonin on glucose homeostasis in young male Zucker diabetic fatty (ZDF) rats, an experimental model of metabolic syndrome and type 2 diabetes mellitus (T2DM). ZDF rats (n=30) and lean litterm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ecfbd41fbd2bb9e70171a0913082bce9
https://doi.org/10.1111/j.1600-079x.2011.00928.x

Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats

Autor: Aroa Jiménez-Aranda, Mohamed Tassi, Gumersindo Fernández-Vázquez, Russel J. Reiter, Ahmad Agil, Mazen M. El-Hammadi, Walied Abdo

Publikováno v: Journal of pineal research. 59(1)

Hepatic mitochondrial dysfunction is thought to play a role in the development of liver steatosis and insulin resistance, which are both common characteristics of obesity and type 2 diabetes mellitus (T2DM). It was hypothesized that the antioxidant p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f07f3f77587b3e88b4e643e922a006d
https://pubmed.ncbi.nlm.nih.gov/25904243