Výsledky vyhledávání - "Gulzar, Adnan"

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Log-periodic oscillations as real-time signatures of hierarchical dynamics in proteins

Autor: Dorbath, Emanuel, Gulzar, Adnan, Stock, Gerhard

The time-dependent relaxation of a dynamical system may exhibit a power-law behavior that is superimposed by log-periodic oscillations. Sornette [Phys. Rep. 297, 239 (1998)] showed that this behavior can be explained by a discrete scale invariance of

Externí odkaz: http://arxiv.org/abs/2311.11839

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Nonequilibrium Modeling of the Elementary Step in PDZ3 Allosteric Communication

Autor: Ali, Ahmed A. A. I., Gulzar, Adnan, Wolf, Steffen, Stock, Gerhard

Publikováno v: The Journal of Physical Chemistry Letters 13.42 (2022): 9862-9868

While allostery is of paramount importance for protein signaling and regulation, the underlying dynamical process of allosteric communication is not well understood. PDZ3 domain represents a prime example of an allosteric single-domain protein, as it

Externí odkaz: http://arxiv.org/abs/2209.07829

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Real-time observation of ligand-induced allosteric transitions in a PDZ domain

Autor: Bozovic, Olga, Zanobini, Claudio, Gulzar, Adnan, Jankovic, Brankica, Buhrke, David, Post, Matthias, Wolf, Steffen, Stock, Gerhard, Hamm, Peter

Publikováno v: Proc. Natl. Acad. Sci. USA 117, 26031-26039 (2020)

While allostery is of paramount importance for protein regulation, the underlying dynamical process of ligand (un)binding at one site, resulting time evolution of the protein structure, and change of the binding affinity at a remote site is not well

Externí odkaz: http://arxiv.org/abs/2008.01625

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