Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gulnaz Gurtskaia"'
Autor:
Nana Tsiklauri, Natia Pirkulashvili, Ivliane Nozadze, Marina Nebieridze, Gulnaz Gurtskaia, Elene Abzianidze, Merab G. Tsagareli
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background In the past decade several studies have reported that in some brain areas, particularly, in the midbrain periaqueductal gray matter, rostral ventro-medial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hipp
Externí odkaz:
https://doaj.org/article/10635d5939374df3b7a52372f23559de
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 668-673 (2016)
Transient receptor potential (TRP) cation channels have been extensively investigated as targets for analgesic drug discovery. Because some non-steroidal anti-inflammatory drugs (NSAIDs) are structural analogs of prostaglandins (mediators of inflamma
Externí odkaz:
https://doaj.org/article/f9d83f967949446d99d5ddc9d4a25579
Publikováno v:
Medical Sciences, Vol 7, Iss 4, p 62 (2019)
Persistent itch (pruritus) accompanying dermatologic and systemic diseases can significantly impair the quality of life. It is well known that itch is broadly categorized as histaminergic (sensitive to antihistamine medications) or non-histaminergic.
Externí odkaz:
https://doaj.org/article/0f64f920912b4a1e839221ee36f994d8
Autor:
Nana Tsiklauri, Merab G. Tsagareli, Gulnaz Gurtskaia, Ivliane Nozadze, Earl Carstens, Mirela Iodi Carstens
Publikováno v:
Neuroscience
Acute itch is elicited by histamine, as well as non-histaminergic itch mediators including chloroquine, BAM8-22 and Ser-Leu-Ile-Gly-Arg-Leu (SLIGRL). When injected intradermally, histamine binds to histamine H1 and H4 receptors that activate transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf85778c7ea5c237ae0dc33dae32156
https://escholarship.org/uc/item/9d43v52d
https://escholarship.org/uc/item/9d43v52d
Publikováno v:
Medical Sciences
Volume 7
Issue 4
Medical Sciences, Vol 7, Iss 4, p 62 (2019)
Volume 7
Issue 4
Medical Sciences, Vol 7, Iss 4, p 62 (2019)
Persistent itch (pruritus) accompanying dermatologic and systemic diseases can significantly impair the quality of life. It is well known that itch is broadly categorized as histaminergic (sensitive to antihistamine medications) or non-histaminergic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2e532fa449f70316c2041cb88dcbc2
Autor:
Gulnaz Gurtskaia, Marina Nebieridze, E Abzianidze, Natia Pirkulashvili, Nana Tsiklauri, Merab G. Tsagareli, Ivliane Nozadze
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-7 (2018)
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-7 (2018)
Background In the past decade several studies have reported that in some brain areas, particularly, in the midbrain periaqueductal gray matter, rostral ventro-medial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hippocampus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7c02aa76bd418289087c556b527c80
https://doi.org/10.1186/s40360-017-0193-y
https://doi.org/10.1186/s40360-017-0193-y
Autor:
Gulnaz Gurtskaia
Publikováno v:
Annual Research & Review in Biology. 4:1887-1901
Purpose of Review: One of the vital functions of the nervous system is to provide information about the threat of injury . The sensation of pain by its inherent aversive nature, contributes to this function. The mainstay of medical pain therapy remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c89f1c144fe2d5199f0e91ec720b847a
https://doi.org/10.9734/arrb/2014/8001
https://doi.org/10.9734/arrb/2014/8001
Publikováno v:
Pharmacological reports : PR. 69(1)
Background In the past decade it has been shown that tolerance develops to the antinociceptive effect of repeated systemic administration of commonly used non-steroidal anti-inflammatory drugs (NSAIDs) in acute pain models using rats. This is similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb8b41749464321954a47fca8747743
https://pubmed.ncbi.nlm.nih.gov/27923161
https://pubmed.ncbi.nlm.nih.gov/27923161
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
Frontiers in Neuroscience
Frontiers in Neuroscience
Repeated injection of opioid analgesics can lead to a progressive loss of effect. This phenomenon is known as tolerance. Several lines of investigations have shown that systemic, intraperitoneal administration or the microinjection of non-opioid anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e1f46041fc44757d7f17f92614446a