A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs.

Autor: Neal EH; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Marinelli NA; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN, USA., Shi Y; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., McClatchey PM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Balotin KM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Gullett DR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Hagerla KA; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Bowman AB; School of Health Sciences, Purdue University, West Lafayette, IN, USA., Ess KC; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA., Wikswo JP; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, USA; Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN, USA., Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA. Electronic address: ethan.s.lippmann@vanderbilt.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2019 Jun 11; Vol. 12 (6), pp. 1380-1388.