One-Pot Synthesis of Chromone-2-carboxylate Scaffold: An Important Pharmacophore with Diverse Biological Properties.

Autor: Tummanapalli S; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Punna SK; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Gulipalli KC; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Endoori S; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Bodige S; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Pommidi AK; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Medaboina S; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Choppadandi S; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Boya R; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Ganapathi VK; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Mamindla DY; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Konakalla R; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Bodala GK; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Bakangari MR; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Kottam SD; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Jarikote D; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Potewar T; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India., Valluri M; Curia India Pvt. Ltd (Formerly Albany Molecular Research Hyderabad Research Centre), Plot # 9, MN Park, Turkapally, Shameerpet, Genome Valley, RR District, Hyderabad 500 078, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2023 Jul 07; Vol. 88 (13), pp. 8387-8399. Date of Electronic Publication: 2023 Jun 26.

Design, synthesis, in silico and in vitro evaluation of thiophene derivatives: A potent tyrosine phosphatase 1B inhibitor and anticancer activity.

Autor: Gulipalli KC; Department of Chemistry, K L University, Green Fields, Vaddeswaram, Guntur 522502, India., Bodige S; Department of Chemistry, K L University, Green Fields, Vaddeswaram, Guntur 522502, India., Ravula P; Department of Pharmaceutical Chemistry, Gurunanak Institutions Technical Campus, School of Pharmacy, Hyderabad, India., Endoori S; Department of Chemistry, K L University, Green Fields, Vaddeswaram, Guntur 522502, India., Vanaja GR; Department of Animal Biology, University of Hyderabad, Hyderabad 500046, India., Suresh Babu G; Department of Animal Biology, University of Hyderabad, Hyderabad 500046, India., Narendra Sharath Chandra JN; Department of Pharmaceutical Chemistry, Bharath Institute of Technology-Pharmacy, Hyderabad, India., Seelam N; Department of Chemistry, K L University, Green Fields, Vaddeswaram, Guntur 522502, India. Electronic address: nareshvarma.klu@gmail.com.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Aug 01; Vol. 27 (15), pp. 3558-3564. Date of Electronic Publication: 2017 May 24.