Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gulesi, Ayanoglu"'
Autor:
Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) wer
Externí odkaz:
https://doaj.org/article/3c551d2d1a814a3d84819bbd3a685652
Autor:
Maribel Beaumont, Daniela Tomazela, Douglas Hodges, Grigori Ermakov, Edward Hsieh, Isabel Figueroa, On-Yee So, Yaoli Song, Huiping Ma, Svetlana Antonenko, Wondwessen Mengesha, Yi Wei Zhang, Shuli Zhang, SuChun Hseih, Gulesi Ayanoglu, Xiaoyan Du, Eric Rimmer, Michael Judo, Franklin Vives, Jennifer H. Yearley, Christina Moon, Anthony Manibusan, Nick Knudsen, Andy Beck, Damien Bresson, Dennis Gately, Divas Neupane, Enrique Escandón
Publikováno v:
AAPS Open, Vol 4, Iss 1, Pp 1-17 (2018)
Abstract Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic
Externí odkaz:
https://doaj.org/article/d0889a1254a541b881e9c5aca5d58fd2
Autor:
Laurence Fayadat-Dilman, Christine Andrews, Gulesi Ayanoglu, Liming Liu, Robert A. Kastelein, Aarron T. Willingham, Sabine Le Saux, Svetlana Sadekova, Dan Malashock, Hans van Eenennaam, Sophie Li, Ying Yu, Soonmo Peter Kang, Beth Hutchins, Andrea van Elsas, John Dulos, Rene De Waal Malefyt, Julie Lee, Frederique M. Poulet, Gregory J. Carven, Constance Cullen, Gary C. Starling, Mark Hsieh, Danuta J. Herzyk, Michel Streuli, Mark A. McCoy, George Soder
Publikováno v:
Molecular Cancer Therapeutics. 19:1298-1307
The programmed cell death 1 (PD-1) pathway represents a major immune checkpoint, which may be engaged by cells in the tumor microenvironment to overcome active T-cell immune surveillance. Pembrolizumab (Keytruda®, MK-3475) is a potent and highly sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44ee4cad68943c640dee7d7ddd1ef5be
https://doi.org/10.1158/1535-7163.mct-19-0774
https://doi.org/10.1158/1535-7163.mct-19-0774
Autor:
Philip E. Brandish, Anthony Palmieri, Gulesi Ayanoglu, Jeanne Baker, Raphael Bueno, Alan Byford, Michael Caniga, Craig Chappell, Holly Cherwinski, Daniel J. Cua, Xiaoyan Du, Laurence Fayadat-Dilman, Brian E. Hall, Hassan Issafras, Barbara Joyce-Shaikh, Veronica Juan, Rachel D. Levy, Andrey Loboda, Jared Lunceford, Carl Mieczkowski, Michael Meehl, Yujie Qu, Michael Rosenzweig, Latika Singh, Peter Stivers, Peter J. Tramontozzi, Kimberly Vermilya, Karin Vroom, Douglas C. Wilson, Chungsheng Zhang, Jie Zhang-Hoover
Tumor myeloid suppressor cells impede response to T cell checkpoint immunotherapy. Immunoglobulin-like transcript 3 (ILT3, gene name, LILRB4) expressed on dendritic cells (DCs) promotes antigen-specific tolerance. Circulating monocytic MDSCs that exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72b5e16ef1b15fd1e3d724e4d5c0bdd7
https://doi.org/10.1101/2021.12.18.472552
https://doi.org/10.1101/2021.12.18.472552
Autor:
Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini
Publikováno v:
The Journal of clinical investigation. 132(8)
Interleukin-10 (IL-10) is an immunosuppressive cytokine that signals through STAT3 to regulate T follicular helper (Tfh) cell differentiation and germinal center formation. In SIV-infected macaques, levels of IL-10 in plasma and lymph nodes (LNs) wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d087014e3ecae8c172e5cd6e4002a185
https://pubmed.ncbi.nlm.nih.gov/35230978
https://pubmed.ncbi.nlm.nih.gov/35230978
Autor:
Suzette Farber-Katz, Tong Zhao, Gulesi Ayanoglu, Jay M. Stewart, Paul E. Carrington, Catherine Psaras, Franklin Vives, Sawarin Laotaweerungsawat, Santosh C. Sutradhar, Yi Chen, Nina Xiaoyan Li, Audrey Phone, Ricardo Lamy, Dahui Ma
Publikováno v:
Translational vision science & technology, vol 9, iss 10
Translational Vision Science & Technology
Translational Vision Science & Technology
Author(s): Lamy, Ricardo; Farber-Katz, Suzette; Vives, Franklin; Ayanoglu, Gulesi; Zhao, Tong; Chen, Yi; Laotaweerungsawat, Sawarin; Ma, Dahui; Phone, Audrey; Psaras, Catherine; Li, Nina Xiaoyan; Sutradhar, Santosh; Carrington, Paul E; Stewart, Jay M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9b34574261d7ea85845bada86722cd
https://escholarship.org/uc/item/4t4022cv
https://escholarship.org/uc/item/4t4022cv
Autor:
Beth, Hutchins, Gary C, Starling, Mark A, McCoy, Danuta, Herzyk, Frederique M, Poulet, John, Dulos, Liming, Liu, Soonmo Peter, Kang, Laurence, Fayadat-Dilman, Mark, Hsieh, Christine L, Andrews, Gulesi, Ayanoglu, Constance, Cullen, Rene de Waal, Malefyt, Robert A, Kastelein, Sabine Le, Saux, Julie, Lee, Sophie, Li, Dan, Malashock, Svetlana, Sadekova, George, Soder, Hans, van Eenennaam, Aarron, Willingham, Ying, Yu, Michel, Streuli, Gregory J, Carven, Andrea, van Elsas
Publikováno v:
Molecular cancer therapeutics. 19(6)
The programmed cell death 1 (PD-1) pathway represents a major immune checkpoint, which may be engaged by cells in the tumor microenvironment to overcome active T-cell immune surveillance. Pembrolizumab (Keytruda®, MK-3475) is a potent and highly sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10d0b6eca5fefc531e03f4842302e6d9
https://pubmed.ncbi.nlm.nih.gov/32229606
https://pubmed.ncbi.nlm.nih.gov/32229606
Autor:
Gulesi Ayanoglu, Linda Liang, Stephen F. Previs, Anita Y. H. Lee, Sandra C. Souza, Haihong Zhou, Omar F Laterza, Jose Castro-Perez, Michael Judo, Tatyana Churakova, Michael E. Lassman, Monika J. Bak, Derek L Chappell
Publikováno v:
Clinical Chemistry. 62:227-235
BACKGROUND Proglucagon-derived peptides (PGDPs), which include glucagon-like peptide (GLP)-1, glucagon, and oxyntomodulin, are key regulators of glucose homeostasis and satiety. These peptide hormones are typically measured with immuno-based assays (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6c4dadb5cd414ba1b47be9a71d88d0
https://doi.org/10.1373/clinchem.2015.244251
https://doi.org/10.1373/clinchem.2015.244251
Autor:
Huiping Ma, SuChun Hseih, Shuli Zhang, Gulesi Ayanoglu, Christina Moon, Svetlana Antonenko, Damien Bresson, Isabel Figueroa, Eric Rimmer, Enrique Escandón, Edward Hsieh, Maribel Beaumont, Anthony Manibusan, Franklin Vives, Grigori Ermakov, Daniela M. Tomazela, Jennifer H. Yearley, Andrew H. Beck, Wondwessen Mengesha, Yaoli Song, On-Yee So, Divas Neupane, Michael Judo, Douglas Hodges, Yi Wei Zhang, Dennis Gately, Xiaoyan Du, Nick Knudsen
Publikováno v:
AAPS Open, Vol 4, Iss 1, Pp 1-17 (2018)
Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd018dbd2cdf16eeb7c9cfacdd32e689
https://doi.org/10.1186/s41120-018-0026-0
https://doi.org/10.1186/s41120-018-0026-0
Application of Proof-of-Mechanism Biomarkers (POM) in Design and Development of Biologics Modalities
Publikováno v:
Development of Antibody-Based Therapeutics ISBN: 9789811304958
A science-based approach for translation of exposure–response data is vital for effective advancement of antibody-based therapeutics. A critical consideration during the development of antibody-based therapeutics is selection and evaluation of rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd45ea766ccc94b0fe9fb1cc4a55f0c
https://doi.org/10.1007/978-981-13-0496-5_9
https://doi.org/10.1007/978-981-13-0496-5_9