Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Gulcin Ozer"'
Autor:
Janek S. Walker, Zachary A. Hing, Steven Sher, James Cronin, Katie Williams, Bonnie Harrington, Jordan N. Skinner, Casey B. Cempre, Charles T. Gregory, Alexander Pan, Max Yano, Larry P. Beaver, Brandi R. Walker, Jadwiga M. Labanowska, Nyla A. Heerema, Krzysztof Mrózek, Jennifer A. Woyach, Amy S. Ruppert, Amy Lehman, Hatice Gulcin Ozer, Vincenzo Coppola, Pearlly Yan, John C. Byrd, James S. Blachly, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Some genes that are part of balanced translocations are reported as drivers for tumourigenesis. Here, the authors report a translocation involving MTCP1 in chronic lymphocytic leukemia and show that MTCP1 overexpression leads to the disease in a muri
Externí odkaz:
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0
Autor:
Qingwei Wang, Hatice Gulcin Ozer, Bowen Wang, Mengxue Zhang, Go Urabe, Yitao Huang, K. Craig Kent, Lian-Wang Guo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 54-66 (2021)
Bromodomain protein BRD4 reads histone acetylation (H3K27ac), an epigenomic mark of transcription enhancers. CCAAT enhancer binding protein delta (CEBPD) is a transcription factor typically studied in metabolism. While both are potent effectors and p
Externí odkaz:
https://doaj.org/article/c4501990cf32428e9ba19ad13169e516
Autor:
Janek S. Walker, Zachary A. Hing, Bonnie Harrington, Jordan Baumhardt, Hatice Gulcin Ozer, Amy Lehman, Brian Giacopelli, Larry Beaver, Katie Williams, Jordan N. Skinner, Casey B. Cempre, Qingxiang Sun, Sharon Shacham, Benjamin R. Stromberg, Matthew K. Summers, Lynne V. Abruzzo, Laura Rassenti, Thomas J. Kipps, Sameer Parikh, Neil E. Kay, Kerry A. Rogers, Jennifer A. Woyach, Vincenzo Coppola, Yuh Min Chook, Christopher Oakes, John C. Byrd, Rosa Lapalombella
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Abstract Background Exportin 1 (XPO1/CRM1) is a key mediator of nuclear export with relevance to multiple cancers, including chronic lymphocytic leukemia (CLL). Whole exome sequencing has identified hot-spot somatic XPO1 point mutations which we foun
Externí odkaz:
https://doaj.org/article/5d10b5b0f27b4de5a2529f4fedcb0538
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Small changes in a protein’s core packing produce changes in function, and even small changes in function bias species fitness and survival. Therefore individually deleterious mutations should be evolutionarily coupled with compensating mutations t
Externí odkaz:
https://doaj.org/article/83ff09e307554c0881f8a35fbc01fe57
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S24, Pp 1-7 (2019)
Abstract Background RNA sequencing has become an increasingly affordable way to profile gene expression patterns. Here we introduce a workflow implementing several open-source softwares that can be run on a high performance computing environment. Res
Externí odkaz:
https://doaj.org/article/b4ab229d265e4cfaa7012c638c2ea2cc
Autor:
Marius Bill, Chinmayee Goda, Felice Pepe, Hatice Gulcin Ozer, Betina McNeil, Xiaoli Zhang, Malith Karunasiri, Rohan Kulkarni, Sonu Kalyan, Dimitrios Papaioannou, Gregory Ferenchak, Ramiro Garzon, James E. Bradner, Guido Marcucci, Michael A. Caligiuri, Adrienne M. Dorrance
Publikováno v:
Haematologica, Vol 106, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/84dca5e166e942fb88993103e6ebaccf
Autor:
Rosa Lapalombella, John C. Byrd, Gideon Bollag, Ewy A. Mathé, Chao Zhang, Prabha Ibrahim, Gaston Habets, Bernice Matusow, Marika Nespi, Hamid Rezaei, Laura Sanftner, Jason Walters, Christina Tantoy, Adhirai Marimuthu, Todd Ewing, Ken Dong, Garson Tsang, Heidi Carias, Rafe Shellooe, Paul Severson, Songyuan Shi, Wayne Spevak, Ying Zhang, Yan Ma, Jiazhong Zhang, Lianbo Yu, Amy M. Lehman, Deepa Sampath, Jennifer A. Woyach, David M. Lucas, Virginia M. Goettl, Larry Beaver, Matthew Cannon, Elizabeth Baskin, Lindsey Brinton, Robert A. Baiocchi, Lapo Alinari, Tzung-Huei Lai, Katie Williams, Nicole R. Grieselhuber, Shaneice Mitchell, Bonnie Harrington, James S. Blachly, Zachary A. Hing, Ben Powell, Dalia El-Gamal, Hatice Gulcin Ozer
Supplementary Figures S1-S7 with captions and Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7533dd2eb9678807fc10bb97d5617e
https://doi.org/10.1158/2159-8290.22532987
https://doi.org/10.1158/2159-8290.22532987
Autor:
Rosa Lapalombella, John C. Byrd, Gideon Bollag, Ewy A. Mathé, Chao Zhang, Prabha Ibrahim, Gaston Habets, Bernice Matusow, Marika Nespi, Hamid Rezaei, Laura Sanftner, Jason Walters, Christina Tantoy, Adhirai Marimuthu, Todd Ewing, Ken Dong, Garson Tsang, Heidi Carias, Rafe Shellooe, Paul Severson, Songyuan Shi, Wayne Spevak, Ying Zhang, Yan Ma, Jiazhong Zhang, Lianbo Yu, Amy M. Lehman, Deepa Sampath, Jennifer A. Woyach, David M. Lucas, Virginia M. Goettl, Larry Beaver, Matthew Cannon, Elizabeth Baskin, Lindsey Brinton, Robert A. Baiocchi, Lapo Alinari, Tzung-Huei Lai, Katie Williams, Nicole R. Grieselhuber, Shaneice Mitchell, Bonnie Harrington, James S. Blachly, Zachary A. Hing, Ben Powell, Dalia El-Gamal, Hatice Gulcin Ozer
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b606648bc10ea30723eacd8e307e1ba
https://doi.org/10.1158/2159-8290.22532984.v1
https://doi.org/10.1158/2159-8290.22532984.v1
Autor:
Amy S. Ruppert, Larry Beaver, Bonnie K. Harrington, Janek S. Walker, Brandi R. Walker, Katie Williams, James Cronin, Zachary A. Hing, Alexander Pan, Jordan N. Skinner, Jennifer A. Woyach, Nyla A. Heerema, Steven Sher, Amy Lehman, Charles Thomas Gregory, Vincenzo Coppola, Rosa Lapalombella, Krzysztof Mrózek, Max Yano, Pearlly S. Yan, Hatice Gulcin Ozer, James S. Blachly, Jadwiga Labanowska, John C. Byrd, Casey Cempre
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Rare, recurrent balanced translocations occur in a variety of cancers but are often not functionally interrogated. Balanced translocations with the immunoglobulin heavy chain locus (IGH; 14q32) in chronic lymphocytic leukemia (CLL) are infrequent but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4020fc2f6408fa397a551b9d41261e40
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0
Autor:
Hatice Gulcin Ozer, Aisulu Usubalieva, Adrienne Dorrance, Ayse Selen Yilmaz, Michael Caligiuri, Guido Marcucci, Kun Huang
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 3, Pp 105-111 (2015)
Externí odkaz:
https://doaj.org/article/5e68d5dfe88d4556a6272216820a2424