Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gulcin, Tezcan"'
Autor:
Shaimaa Hamza, Ekaterina E. Garanina, Layaly Shkair, Mohammad Alsaadi, Svetlana F. Khaiboullina, Gulcin Tezcan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 299 (2024)
The NLR family pyrin domain containing 3 (NLRP3) promotes the growth of colorectal cancer (CRC). However, the therapeutic effect of NLRP3 inhibition on CRC cell progression is controversial. This study comparatively investigated the therapeutic effec
Externí odkaz:
https://doaj.org/article/969f9206b85c4d9ba4e0a4357e6377eb
Autor:
Melis Ercelik, Cagla Tekin, Gulcin Tezcan, Secil Ak Aksoy, Ahmet Bekar, Hasan Kocaeli, Mevlut Ozgur Taskapilioglu, Pınar Eser, Berrin Tunca
Publikováno v:
Life, Vol 13, Iss 2, p 470 (2023)
The effects of Olea europaea leaf extract (OLE) phenolics, including oleuropein (OL), hydroxytyrosol (HT), tyrosol (TYR), and rutin against glioblastoma (GB), independently and in combination with temozolomide (TMZ), were investigated in T98G and A17
Externí odkaz:
https://doaj.org/article/fe63ab2695e84b7eb89973c6854081af
Autor:
Gulcin Tezcan, Fatma Ozdemir, Gulsah Cecener, Secil Ak Aksoy, Berrin Tunca, Erol Armagan, Ozlem Koksal, Pinar Cinar Sert
Publikováno v:
Van Tıp Dergisi, Vol 26, Iss 2, Pp 167-176 (2019)
INTRODUCTION: miR-1 miR-133a and miR-133b release into the circulation during the early stages of acute coronary syndrome (ACS). However, their discriminative expression pattern in ST-elevation myocardial infarction (STEMI) and Non-ST-elevation myoca
Externí odkaz:
https://doaj.org/article/3a8317350f91467483bc45c9011c6fac
Autor:
Gulcin Tezcan, Ekaterina E. Garanina, Mohammad Alsaadi, Zarema E. Gilazieva, Ekaterina V. Martinova, Maria I. Markelova, Svetlana S. Arkhipova, Shaimaa Hamza, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
IntroductionDysregulation of NLRP3 inflammasome complex formation can promote chronic inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation on tumor progression remains controversial. Therefore, we sought to dete
Externí odkaz:
https://doaj.org/article/d346e250934c456b8d0b7273450e35c3
Autor:
Omer Gokay Argadal, Melis Mutlu, Secil Ak Aksoy, Hasan Kocaeli, Berrin Tunca, Muhammet Nafi Civan, Unal Egeli, Gulsah Cecener, Ahmet Bekar, Mevlut Ozgur Taskapilioglu, Cagla Tekin, Gulcin Tezcan, Sahsine Tolunay
Publikováno v:
Biomolecules & Biomedicine, Vol 20, Iss 1 (2020)
Primary glioblastoma (GB) is the most aggressive type of brain tumors. While mutations in isocitrate dehydrogenase (IDH) genes are frequent in secondary GBs and correlate with a better prognosis, most primary GBs are IDH wild-type. Recent studies hav
Externí odkaz:
https://doaj.org/article/c58fd194674d45f3a11d086ac335a20d
Autor:
Mohammad Alsaadi, Gulcin Tezcan, Ekaterina E. Garanina, Shaimaa Hamza, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 852 (2021)
NLR family pyrin domain containing 3 (NLRP3) inflammasome formation is triggered by the damaged mitochondria releasing reactive oxygen species. Doxycycline was shown to regulate inflammation; however, its effect on NLRP3 in cancer remains largely unk
Externí odkaz:
https://doaj.org/article/f7a19754dac749868639ea2b1683af6c
Autor:
Secil Ak Aksoy, Berrin Tunca, Melis Erçelik, Gulcin Tezcan, Ersin Ozturk, Gulsah Cecener, Nesrin Ugras, Tuncay Yilmazlar, Omer Yerci
Publikováno v:
Molecular Biology Reports. 49:11243-11253
This study aimed to investigate the role of long noncoding RNA (LncRNA) expression profiles to predict relapse and 5-FU response in patients with stage I/II colon cancer (CC).The expression level of 15 LncRNA was analyzed in stage I/II colon tumors o
Autor:
Gulcin Tezcan, Ekaterina V. Martynova, Zarema E. Gilazieva, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Inflammation has a crucial role in protection against various pathogens. The inflammasome is an intracellular multiprotein signaling complex that is linked to pathogen sensing and initiation of the inflammatory response in physiological and pathologi
Externí odkaz:
https://doaj.org/article/1ea27a3a8c8245fc8441e1933b60b5a6
Autor:
Shaimaa Hamza, Ekaterina E. Garanina, Mohammad Alsaadi, Svetlana F. Khaiboullina, Gulcin Tezcan
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4846
Volume 24
Issue 5
Pages: 4846
NOD-like receptor protein 3 (NLRP3) may contribute to the growth and propagation of breast cancer (BC). The effect of estrogen receptor-α (ER-α), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) on NLRP3 activation in
Autor:
Ferah Budak, Salih Haldun Bal, Gulcin Tezcan, Emin Halis Akalın, Abdullah Yılmaz, Pınar Hız, Haluk Barbaros Oral
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198659 (2018)
Brucellosis is a serious infectious disease that continues to be a significant cause of morbidity worldwide and across all ages. Despite early diagnosis and treatment, 10-30% of patients develop chronic brucellosis. Although there have been recent ad
Externí odkaz:
https://doaj.org/article/76e60b92a57741c596a6c04dedfd2e9c