Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gulcan Kocak"'
Autor:
Roberto Cappai, Greg A. Cranston, Giuseppe D. Ciccotosto, Colin L. Masters, Peter J. Crouch, Gulcan Kocak, Tai Du, Anthony R. White
Publikováno v:
Free Radical Biology and Medicine. 44:44-55
Loss of intracellular neuronal glutathione (GSH) is an important feature of neurodegenerative disorders including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. The consequences of GSH depletion include increased oxidati
Autor:
Gaik Beng Kok, Ashley I. Bush, Roberto Cappai, Gulcan Kocak, Robert A. Cherny, Irene Volitakis, Colin L. Masters, Kevin J. Barnham, Elisabeth Gautier, Darryl Carrington
Publikováno v:
Alzheimer's & Dementia. 2
Autor:
Roberto Cappai, Feda E. Ali, Irene Volitakis, Robert A. Cherny, John D. Wade, Gulcan Kocak, Danielle G. Smith, Colin L. Masters, Yuen-Han Lam, Deborah J. Tew, Kevin J. Barnham, Ashley I. Bush, Nicholas A. Williamson, Giuseppe D. Ciccotosto, Frances Separovic, Darryl Carrington, Colin J. Barrow, Anna K. Tickler, Cyril C. Curtain
Publikováno v:
The Journal of biological chemistry. 278(44)
The amyloid beta peptide is toxic to neurons, and it is believed that this toxicity plays a central role in the progression of Alzheimer's disease. The mechanism of this toxicity is contentious. Here we report that an Abeta peptide with the sulfur at
Autor:
Xian-guo Guo, Mary-Anne Siomos, Gulcan Kocak, Michael Foley, Naomi Vittoria. Campanale, Leann Tilley, Vicki Papalexis
Publikováno v:
Molecular and biochemical parasitology. 115(1)
The histidine-rich protein 2 (PfHRP2) of Plasmodium falciparum has been implicated in the detoxification of ferriprotoporphyrin IX (FP) moieties that are produced as by-products of the digestion of haemoglobin. In this work, we have used a spectrosco
Autor:
Michael Foley, Gabriele M. König, Marion Gurrath, Gulcan Kocak, Gregory M. Neumann, Leann Tilley, Anthony D. Wright, Paul Loria, Huiqin Wang
Publikováno v:
Journal of medicinal chemistry. 44(6)
A series of terpene isonitriles, isolated from marine sponges, have previously been shown to exhibit antimalarial activities. Molecular modeling studies employing 3D-QSAR with receptor modeling methodologies performed with these isonitriles showed th