IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection.

Autor: Han F; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Gulam MY; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Zheng Y; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Zulhaimi NS; Centre of Excellence for Research in AIDS (CERiA), University of Malaya, Kuala Lumpur, Malaysia.; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Sia WR; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., He D; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Ho A; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Hadadi L; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Liu Z; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Qin P; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Lobie PE; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China., Kamarulzaman A; Centre of Excellence for Research in AIDS (CERiA), University of Malaya, Kuala Lumpur, Malaysia.; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Wang LF; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Sandberg JK; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Lewin SR; Peter Doherty Institute for Infection and Immunity, Melbourne University, Victoria, Australia., Rajasuriar R; Centre of Excellence for Research in AIDS (CERiA), University of Malaya, Kuala Lumpur, Malaysia.; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; Peter Doherty Institute for Infection and Immunity, Melbourne University, Victoria, Australia., Leeansyah E; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.; Precision Medicine and Healthcare Research Centre, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China.; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Oct 20; Vol. 13, pp. 985385. Date of Electronic Publication: 2022 Oct 20 (Print Publication: 2022).

Parkinson's Disease-Specific Autoantibodies against the Neuroprotective Co-Chaperone STIP1.

Autor: Tan JSY; Neuroscience and Behavioural Disorders Department, Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Lee B; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Lim J; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Ma DR; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore., Goh JX; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore., Goh SY; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore., Gulam MY; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore., Koh SM; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Lee WW; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Feng L; Centre for Health Longevity, National University Hospital, Singapore 119074, Singapore.; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore., Wang Q; Department of Neurology, Zhujiang Hospital, Southern Medical University, Guangdong 510282, China., Chao Y; Neuroscience and Behavioural Disorders Department, Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore., Rötzschke O; Singapore Immunology Network (SIgN), A*STAR, Singapore 138648, Singapore., Tan EK; Neuroscience and Behavioural Disorders Department, Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Neurology, Singapore General Hospital, Singapore 169608, Singapore.; National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.

Publikováno v: Cells [Cells] 2022 May 16; Vol. 11 (10). Date of Electronic Publication: 2022 May 16.

Corrigendum: Gut-Brain Axis: Potential Factors Involved in the Pathogenesis of Parkinson's Disease.

Autor: Chao YX; Department of Neurology, National Neuroscience Institute, Singapore, Singapore.; Department of Neurology, Singapore General Hospital, Singapore, Singapore.; Duke NUS Medical School, Singapore, Singapore., Gulam MY; Department of Neurology, National Neuroscience Institute, Singapore, Singapore., Chia NSJ; Department of Neurology, National Neuroscience Institute, Singapore, Singapore., Feng L; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Rotzschke O; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Tan EK; Department of Neurology, National Neuroscience Institute, Singapore, Singapore.; Department of Neurology, Singapore General Hospital, Singapore, Singapore.; Duke NUS Medical School, Singapore, Singapore.

Publikováno v: Frontiers in neurology [Front Neurol] 2020 Nov 27; Vol. 11, pp. 625446. Date of Electronic Publication: 2020 Nov 27 (Print Publication: 2020).

Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli.

Autor: Boulouis C; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Sia WR; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Gulam MY; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Teo JQM; Department of Pharmacy, Singapore General Hospital, Singapore, Singapore., Png YT; Department of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore., Phan TK; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia., Mak JYW; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Queensland, Brisbane, Queensland, Australia., Fairlie DP; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Queensland, Brisbane, Queensland, Australia., Poon IKH; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia., Koh TH; Department of Microbiology, Singapore General Hospital, Singapore, Singapore., Bergman P; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institutet, Stockholm, Sweden., Lim CM; Department of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.; Surgery Academic Clinical Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Wang LF; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore., Kwa ALH; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.; Department of Pharmacy, Singapore General Hospital, Singapore, Singapore., Sandberg JK; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Leeansyah E; Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore.; Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, Peoples' Republic of China.

Publikováno v: PLoS biology [PLoS Biol] 2020 Jun 08; Vol. 18 (6), pp. e3000644. Date of Electronic Publication: 2020 Jun 08 (Print Publication: 2020).

The CD4 ^- CD8 ^- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8 ⁺ MAIT cell pool.

Autor: Dias J; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden., Boulouis C; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden., Gorin JB; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden., van den Biggelaar RHGA; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.; Department of Infectious Diseases and Immunology, Universiteit Utrecht, 3584CL Utrecht, The Netherlands., Lal KG; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910.; Department of Retrovirology, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817., Gibbs A; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden., Loh L; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA 94110.; Department of Microbiology and Immunology, University of Melbourne, Parkville, VIC 3010, Australia., Gulam MY; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169587 Singapore., Sia WR; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169587 Singapore., Bari S; Department of Hematology, Singapore General Hospital, 169608 Singapore., Hwang WYK; Department of Hematology, Singapore General Hospital, 169608 Singapore.; Division of Medical Sciences, National Cancer Centre Singapore, 16910 Singapore.; Program in Cancer and Stem Cell Biology, Duke-National University of Singapore Medical School, 16958 Singapore., Nixon DF; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA 94110.; Department of Microbiology, Immunology, and Tropical Medicine, George Washington University, Washington, DC 20052., Nguyen S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Betts MR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Buggert M; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Eller MA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910.; Department of Retrovirology, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817., Broliden K; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden., Tjernlund A; Unit of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden., Sandberg JK; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden; johan.sandberg@ki.se edwin.leeansyah@ki.se., Leeansyah E; Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden; johan.sandberg@ki.se edwin.leeansyah@ki.se.; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169587 Singapore.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Dec 04; Vol. 115 (49), pp. E11513-E11522. Date of Electronic Publication: 2018 Nov 15.