Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gukui Chen"'
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 30, Iss , Pp 276-278 (2022)
Externí odkaz:
https://doaj.org/article/d928e7156c104cd180dc5020a35980e6
Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa
Autor:
Gukui Chen, Jiashen Zhou, Yili Zuo, Weiping Huo, Juan Peng, Meng Li, Yani Zhang, Tietao Wang, Lin Zhang, Liang Zhang, Haihua Liang
Publikováno v:
eLife, Vol 10 (2021)
Cyclic-di-guanosine monophosphate (c-di-GMP) is an important effector associated with acute-chronic infection transition in Pseudomonas aeruginosa. Previously, we reported a signaling network SiaABCD, which regulates biofilm formation by modulating c
Externí odkaz:
https://doaj.org/article/f32e19be3f794ab58be95c41b882741a
Autor:
Yuying Han, Tietao Wang, Gukui Chen, Qinqin Pu, Qiong Liu, Yani Zhang, Linghui Xu, Min Wu, Haihua Liang
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008198 (2019)
The type VI secretion system (T6SS) is widely distributed in Gram-negative bacteria, whose function is known to translocate substrates to eukaryotic and prokaryotic target cells to cause host damage or as a weapon for interbacterial competition. Pseu
Externí odkaz:
https://doaj.org/article/d47ce78a6a4a4d2696eacae76964793d
Autor:
Gukui Chen, Haihua Liang
Publikováno v:
Microbial Cell, Vol 7, Iss 6, Pp 160-161 (2020)
The bacterial second messenger cyclic-di-GMP (c-di-GMP) controls biofilm formation and other phenotypes relevant to pathogenesis. The human pathogen Pseudomonas aeruginosa encodes 17 diguanylate cyclase (DGCs) proteins which are required for c-di-GMP
Externí odkaz:
https://doaj.org/article/4a2551737f83409c88b207ef2e7f471e
Autor:
Yani Zhang, Chao Zhang, Xiao Du, Yun Zhou, Weina Kong, Gee W. Lau, Gukui Chen, Gurjeet Singh Kohli, Liang Yang, Tietao Wang, Haihua Liang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Glutathione (GSH) is the most abundant antioxidant in all living organisms. Previously, we have shown that a deletion mutant in the glutathione synthetase gene (ΔgshB) decreases the expression of type III secretion system (T3SS) genes of Pseudomonas
Externí odkaz:
https://doaj.org/article/1b1e7cfd3c814400b420a8c8d585b7e9
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pseudomonas aeruginosa is becoming an increasingly prevalent pathogen, capable of causing numerous life threatening infections in immunocompromised patients. The three hierarchically arranged quorum sensing (QS) systems, namely las, rhl, and pqs play
Externí odkaz:
https://doaj.org/article/2aed6713ff8e47d3b5455b8614018a3a
Autor:
Kewei Li, Chang Xu, Yongxin Jin, Ziyu Sun, Chang Liu, Jing Shi, Gukui Chen, Ronghao Chen, Shouguang Jin, Weihui Wu
Publikováno v:
mBio, Vol 4, Iss 6 (2013)
ABSTRACT During initial colonization and chronic infection, pathogenic bacteria encounter distinct host environments. Adjusting gene expression accordingly is essential for the pathogenesis. Pseudomonas aeruginosa has evolved complicated regulatory n
Externí odkaz:
https://doaj.org/article/a7c2d93515bb4bc0a0af15f10e66689a
Publikováno v:
Environmental Microbiology. 22:5402-5413
Pseudomonas aeruginosa produces several proteases, such as an elastase (LasB protease), a LasA protease, and protease IV (PIV), which are thought as significant virulence factors during infection. Regulators of LasA and LasB expression have been iden
Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa
Autor:
Yili Zuo, Lin Zhang, Yani Zhang, Tietao Wang, Liang Zhang, Weiping Huo, Jiashen Zhou, Gukui Chen, Juan Peng, Meng Li, Haihua Liang
Publikováno v:
eLife, Vol 10 (2021)
Cyclic-di-guanosine monophosphate (c-di-GMP) is an important effector associated with acute-chronic infection transition in Pseudomonas aeruginosa. Previously, we reported a signaling network SiaABCD, which regulates biofilm formation by modulating c