Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Guizhong Cui"'
Publikováno v:
Journal of Developmental Biology, Vol 12, Iss 3, p 24 (2024)
The NR2F family, including NR2F1, NR2F2, and NR2F6, belongs to the nuclear receptor superfamily. NR2F family members function as transcription factors and play essential roles in the development of multiple organs or tissues in mammals, including the
Externí odkaz:
https://doaj.org/article/363d282060f449ddafa82c5bdc3f1840
Autor:
Ran Wang, Xianfa Yang, Jiehui Chen, Lin Zhang, Jonathan A. Griffiths, Guizhong Cui, Yingying Chen, Yun Qian, Guangdun Peng, Jinsong Li, Liantang Wang, John C. Marioni, Patrick P. L. Tam, Naihe Jing
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Understanding of the molecular drivers of lineage diversification and tissue patterning during primary germ layer development requires in-depth knowledge of the dynamic molecular trajectories of cell lineages across a series of developmental
Externí odkaz:
https://doaj.org/article/843d895fd4d14dc49ffa9a2deb1ffa4e
Autor:
Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mammalian embryos exhibit sophisticated cellular patterning that is intricately orchestrated at both molecular and cellular level. It has recently become apparent that cells within the animal body display significant heterogeneity, both in t
Externí odkaz:
https://doaj.org/article/eacd895166b546c099665ce9ce153bf8
Autor:
Qing Li, Jiansen Lu, Xidi Yin, Yunjian Chang, Chao Wang, Meng Yan, Li Feng, Yanbo Cheng, Yun Gao, Beiying Xu, Yao Zhang, Yingyi Wang, Guizhong Cui, Luang Xu, Yidi Sun, Rong Zeng, Yixue Li, Naihe Jing, Guo-Liang Xu, Ligang Wu, Fuchou Tang, Jinsong Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract During embryo development, DNA methylation is established by DNMT3A/3B and subsequently maintained by DNMT1. While much research has been done in this field, the functional significance of DNA methylation in embryogenesis remains unknown. He
Externí odkaz:
https://doaj.org/article/37b66ce3400b48938781eebe6eed3937
Publikováno v:
Cell Regeneration, Vol 12, Iss 1, Pp 1-13 (2023)
Abstract The lung is the most critical organ of the respiratory system supporting gas exchange. Constant interaction with the external environment makes the lung vulnerable to injury. Thus, a deeper understanding of cellular and molecular processes u
Externí odkaz:
https://doaj.org/article/81d6549d98f94b8980c9d51e8be8abba
Autor:
Ting Zhang, Wei Ke, Xuan Zhou, Yun Qian, Su Feng, Ran Wang, Guizhong Cui, Ran Tao, Wenke Guo, Yanhong Duan, Xiaobing Zhang, Xiaohua Cao, Yousheng Shu, Chunmei Yue, Naihe Jing
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 1022-1037 (2019)
Summary: Alzheimer's disease (AD) is characterized by memory impairments in its earliest clinical phase. The synaptic loss and dysfunction leading to failures of synaptic networks in AD brain directly cause cognitive deficits of patient. However, it
Externí odkaz:
https://doaj.org/article/761abd4184654fa7846946f0aebe3044
Autor:
Yifei Zhou, Xueqing Wang, Mengjiao Song, Zhidong He, Guizhong Cui, Guangdun Peng, Christoph Dieterich, Adam Antebi, Naihe Jing, Yidong Shen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Decreased autophagy is a hallmark of ageing, but its inter-tissue regulation is poorly understood. Here, Zhou et al. identify mir-83 in C. elegans, which is transported across tissues and suppresses autophagy, contributing to age-related decline.
Externí odkaz:
https://doaj.org/article/80b2ae124c734704ad45ea80c8f0c35c
Autor:
Chang Liu, Ran Wang, Zhisong He, Pierre Osteil, Emilie Wilkie, Xianfa Yang, Jun Chen, Guizhong Cui, Wenke Guo, Yingying Chen, Guangdun Peng, Patrick P.L. Tam, Naihe Jing
Publikováno v:
Stem Cell Reports, Vol 11, Iss 1, Pp 43-57 (2018)
Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model. We captured a self-renewing cell population with enhanced ectoderm
Externí odkaz:
https://doaj.org/article/1e0ecb938c0c49e383516bae07d49f5a
A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis
Autor:
Yuanyuan Xue, Denghui Liu, Guizhong Cui, Yanyan Ding, Daosheng Ai, Suwei Gao, Yifan Zhang, Shengbao Suo, Xiaohan Wang, Peng Lv, Chunyu Zhou, Yizhou Li, Xingwei Chen, Guangdun Peng, Naihe Jing, Jing-Dong J. Han, Feng Liu
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1567-1578.e5 (2019)
Summary: In vertebrates, hematopoiesis occurring in different niches is orchestrated by intrinsic and extrinsic regulators. Previous studies have revealed numerous linear and planar regulatory mechanisms. However, a multi-dimensional transcriptomic a
Externí odkaz:
https://doaj.org/article/7b908c03a0694db89a71d4b6835fc5a4
Autor:
Wei Yu, Xueyan Ma, Jinjin Xu, Andreas Wilhelm Heumüller, Zhaoliang Fei, Xue Feng, Xiaodong Wang, Kuo Liu, Jinhui Li, Guizhong Cui, Guangdun Peng, Hongbin Ji, Jinsong Li, Naihe Jing, Hai Song, Zhiqiang Lin, Yun Zhao, Zuoyun Wang, Bin Zhou, Lei Zhang
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1007977 (2019)
Heart valve disease is a major clinical problem worldwide. Cardiac valve development and homeostasis need to be precisely controlled. Hippo signaling is essential for organ development and tissue homeostasis, while its role in valve formation and mor
Externí odkaz:
https://doaj.org/article/7010330f90d545dcbf61dde5eb272596