BCMA-CD19 bispecific CAR-T therapy in refractory chronic inflammatory demyelinating polyneuropathy

Autor: Wei Zhang, Dan Liu, Tao Zhang, Jiang Cao, Gang Wang, Huizhong Li, Su Zhou, Ruixue Zhang, Yuqiao Wang, Jinyu Li, Zixuan Zhang, Hao Chen, Yong Zhang, Shenyang Zhang, Jie Zu, Xiaopeng Wang, Chuanying Xu, Manli Zhou, Ming Shi, Guiyun Cui, Junnian Zheng

Publikováno v: hLife, Vol 2, Iss 8, Pp 434-438 (2024)

Externí odkaz: https://doaj.org/article/fdf4404f542d4e5fbce99d948c9a4368

TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils

Autor: Tong Shen, Guiyun Cui, Hao Chen, Long Huang, Wei Song, Jie Zu, Wei Zhang, Chuanying Xu, Liguo Dong, Yongmei Zhang

Publikováno v: Neural Regeneration Research, Vol 19, Iss 6, Pp 1375-1384 (2024)

[INLINE:1] Microglia-mediated neuroinflammation is considered a pathological feature of Parkinson’s disease. Triggering receptor expressed on myeloid cell-1 (TREM-1) can amplify the inherent immune response, and crucially, regulate inflammation. In

Externí odkaz: https://doaj.org/article/c704e74950144ab5afdebf640db5d4c7

High-frequency rTMS over bilateral primary motor cortex improves freezing of gait and emotion regulation in patients with Parkinson’s disease: a randomized controlled trial

Autor: Wenjing Song, Zixuan Zhang, Bingchen Lv, Jinyu Li, Hao Chen, Shenyang Zhang, Jie Zu, Liguo Dong, Chuanying Xu, Manli Zhou, Tao Zhang, Ran Xu, Jienan Zhu, Tong Shen, Su Zhou, Chenchen Cui, Shuming Huang, Xi Wang, Yujing Nie, Kainat Aftab, Qihua Xiao, Xueling Zhang, Guiyun Cui, Wei Zhang

Publikováno v: Frontiers in Aging Neuroscience, Vol 16 (2024)

BackgroundFreezing of gait (FOG) is a common and disabling phenomenon in patients with Parkinson’s disease (PD), but effective treatment approach remains inconclusive. Dysfunctional emotional factors play a key role in FOG. Since primary motor cort

Externí odkaz: https://doaj.org/article/651dba6f06f84302bac517a328d4f71d

Efficacy and safety of perampanel as early add-on therapy in Chinese patients with focal-onset seizures: a multicenter, open-label, single-arm study

Autor: Lehong Gao, Qiang Lu, Zan Wang, Wei Yue, Guoping Wang, Xiaoqiu Shao, Yi Guo, Yonghong Yi, Zhen Hong, Yuwu Jiang, Bo Xiao, Guiyun Cui, Feng Gao, Jiasheng Hu, Jianmin Liang, Meiyun Zhang, Yuping Wang

Publikováno v: Frontiers in Neurology, Vol 14 (2023)

BackgroundNo interventional study has been conducted in China to assess efficacy and safety of perampanel in treating Chinese patients with epilepsy, nor has there been any study on perampanel early add-on therapy in China. This interventional study

Externí odkaz: https://doaj.org/article/f006c92e812a42afaf4c7e5baaef7155

Lipid management in ischaemic stroke or transient ischaemic attack in China: result from China National Stroke Registry III

Autor: Xu Zhang, Yongjun Wang, Kangning Chen, Lianbo Gao, Ye Tian, Xu Chen, Yi Guo, Benyan Luo, Yan Wang, Jian Wu, Xiaohong Li, Yong-Jun Wang, Qiang Dong, Huisheng Chen, Wei Wang, Zhengqi Lu, Lijie Ren, Runqing Wang, Juan Feng, Zhangyong Xia, Hao Li, Lihua Wang, Qingwei Zhao, Hong Wang, Ting Wang, Jin Zhou, Xia Meng, Jun Wu, Qing Li, Shizheng Wu, Ping Zhang, Li-Ping Liu, Yue-song Pan, Yi-long Wang, Ming Yu, Guohua Chen, Zhimin Wang, Jianhua Li, Yi Wang, Yi Yang, Xinsheng Han, Songdi Wu, Yongming Chen, Liang Zhao, Qiang Ma, Xiaoying Zhang, Mei Zhang, Limin Wang, Hui Liang, Liping Wang, Jun Zhou, Jie Lin, Yu Geng, Ning Wang, Yun Xu, Jinsheng Zeng, Huijuan Wang, Xueli Cai, Jia Yin, Jun Xu, Feng Qiu, Jun Zhao, Baojun Wang, Hainan Zhang, Zi-Xiao Li, Xing-Quan Zhao, Mingzhi Zhao, Yingchun Wu, Junling Zhang, Xuerong Qiu, Zhongping An, Wenjun Xue, Lili Zhao, Hongyan Li, Junfeng Shi, Tao Gong, Qi Fang, Liyan Liu, Jianfeng Wang, Guang Huang, Chun Wang, Yuwu Zhao, Lei Sheng, Lei Xia, Yan Fang, Xiaoxiang Peng, Yanling Wang, Yangmei Chen, Deqin Geng, Jinfeng Liu, Weirong Li, Yuqing Wei, Yu-Yuan Xu, Jilai Li, Maolin He, Quping Ouyang, Fengchun Yu, Chenlong Wang, Jinli Zhang, Wenqing Wu, Yaoyu Yu, Meiyun Zhang, Junyan Liu, Wanying Shi, Baoquan Lu, Lijun Geng, Shujuan Wang, Ruifang Liu, Fengli Zhao, Xinping Liu, Xuebing Sun, Tianyuan Li, Youming Wang, Xinxia He, Weiqiang Yuan, Ronghua Dou, Lihai Liu, Haisong Du, Cunrui Wang, Xiaofei Chen, Fengyun Hu, Fanping He, Xingchen Wang, Hongjin Li, Mingzong Yan, Guiru Zhang, Yunlin Liu, Yuhui Han, Xianghong Meng, Hongtian Zhang, Congmin Ma, Gexia Liu, Wenxu Zheng, Haitao Chi, Hongbo Xiao, Lijun Xiao, Guozhong Li, Yulan Zhu, Yindong Yang, Xuhai Gong, Qunhui Liu, Shiping Gong, Hongbin Zhou, Haipeng Li, Yong You, Jinsheng Lin, Heqing Zhao, Aixia Zhuang, Kaifu Ke, Zhengxie Dong, Guiyun Cui, Liangqun Rong, Yi Wu, Weiguo Tang, Yanjiang Wang, Wenguang Bu, Xiaohua Cheng, Jifu Cai, Lvli Li, Jianping Niu, Liping Zhan, Runxiu Zhu, Yanhui Du, Yongxia Wen, Yongcai Qu, Yuncheng Wu, Jianren Liu, Qingke Bai, Chaoming He, Weiwen Qiu, Shufang Yao, Xuwen Sun, Ligong Gao, Xianglin Chen, Qiuyan Shi, Zhaochen Li, Tianbao Chen, SuYun Yang, Yazhou Han, Xinxiao Wu, Beihai Jiang, Lizhong Li, Weidong Lou, Weiming Lan, Aihu Zheng, Qifu Bai, Lifang Luan, Liqing Yan, Yanxia Wang, Xuerong Huang, Xiangting Chai, Yanshu Liu, Liangjun You, Hongqin Yang, Dongfang Li, Linying Gui, Aisheng Wu, Dengling Wang, Qinghua Zhang, Yunhong He, Ruiyou Guo, Jijun Teng, Ping Lou, Wei-Qi Chen, Meng-Xing Wang, Yu’an Zou, An’ding Xu, Yinzhou Wang Li Pan, Li’e Wu, Yanru Zhao Li Liu, Xiaoqian Shen

Publikováno v: BMJ Open, Vol 13, Iss 3 (2023)

Objectives The aims of the study were to assess the management of low-density lipoprotein cholesterol (LDL-C) and the goal achievement, as well as to investigate the association between baseline LDL-C level, lipid-lowering treatment (LLT), and stroke

Externí odkaz: https://doaj.org/article/8c5b54741c96430c9ec85dc32ff6f33d