Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Guiyang, Hao"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Copper-67 (t1/2 = 2.58 days) decays by β− ( $$\text{E}_{{\upbeta^{-}\text{max}}}$$ E β - max : 562 keV) and γ-rays (93 keV and 185 keV) rendering it with potential for both radionuclide therapy and single-photon emission computed tomogr
Externí odkaz:
https://doaj.org/article/bd8333e81bf24b33981c236b7c5fe9b7
Autor:
Joseph Vento, Aditi Mulgaonkar, Layton Woolford, Kien Nham, Alana Christie, Aditya Bagrodia, Alberto Diaz de Leon, Raquibul Hannan, Isaac Bowman, Renee M. McKay, Payal Kapur, Guiyang Hao, Xiankai Sun, James Brugarolas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-6 (2019)
Abstract Background Programmed death-ligand 1 (PD-L1) expression in metastatic renal cell carcinoma (RCC) correlates with a worse prognosis, but whether it also predicts responsiveness to anti-PD-1/PD-L1 therapy remains unclear. Most studies of PD-L1
Externí odkaz:
https://doaj.org/article/8c4fd226b847427c8134b2fba28b7121
Autor:
Priyanka Khare, Wei Sun, Sreevidhya Ramakrishnan, Rafal Swiercz, Guiyang Hao, Su-Tang Lo, Kien Nham, Xiankai Sun, Raimund J. Ober, E. Sally Ward
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The prolonged in vivo persistence of antibodies results in high background and poor contrast during their use as molecular imaging agents for positron emission tomography (PET). We have recently described a class of engineered Fc fusion proteins that
Externí odkaz:
https://doaj.org/article/01533df49adc49dc80bf69cd741c757d
Autor:
Xiankai Sun, James Brugarolas, Guiyang Hao, Christina Stevens, I. Alex Bowman, Nirmish Singla, Vanina T. Tcheuyap, Alana Christie, Payal Kapur, Kien Nham, Bing Guan, Layton Woolford, Roy Elias, Aditi Mulgaonkar
Supplementary Table from ImmunoPET Imaging with 89Zr-Labeled Atezolizumab Enables In Vivo Evaluation of PD-L1 in Tumorgraft Models of Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702b5730fdf898803eaa09b5ebbc6071
https://doi.org/10.1158/1078-0432.22489257.v1
https://doi.org/10.1158/1078-0432.22489257.v1
Autor:
Xiankai Sun, James Brugarolas, Guiyang Hao, Christina Stevens, I. Alex Bowman, Nirmish Singla, Vanina T. Tcheuyap, Alana Christie, Payal Kapur, Kien Nham, Bing Guan, Layton Woolford, Roy Elias, Aditi Mulgaonkar
Purpose:Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 and its ligand (PD-1/PD-L1) have transformed the treatment paradigm for metastatic renal cell carcinoma (RCC). However, response rates to ICIs as single agents o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b07b3d292a34ae6f6fc9ab155467fd
https://doi.org/10.1158/1078-0432.c.6532917
https://doi.org/10.1158/1078-0432.c.6532917
Autor:
Xiankai Sun, James Brugarolas, Guiyang Hao, Christina Stevens, I. Alex Bowman, Nirmish Singla, Vanina T. Tcheuyap, Alana Christie, Payal Kapur, Kien Nham, Bing Guan, Layton Woolford, Roy Elias, Aditi Mulgaonkar
Supplementary Figure from ImmunoPET Imaging with 89Zr-Labeled Atezolizumab Enables In Vivo Evaluation of PD-L1 in Tumorgraft Models of Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37118b799a1cfafe59d06c481fac6415
https://doi.org/10.1158/1078-0432.22489272.v1
https://doi.org/10.1158/1078-0432.22489272.v1
Autor:
Aditi Mulgaonkar, Roy Elias, Layton Woolford, Bing Guan, Kien Nham, Payal Kapur, Alana Christie, Vanina T. Tcheuyap, Nirmish Singla, I. Alex Bowman, Christina Stevens, Guiyang Hao, James Brugarolas, Xiankai Sun
Publikováno v:
Clin Cancer Res
Purpose: Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 and its ligand (PD-1/PD-L1) have transformed the treatment paradigm for metastatic renal cell carcinoma (RCC). However, response rates to ICIs as single agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5bbf7f34210ae9cf5f7f4317daa594
https://europepmc.org/articles/PMC9669181/
https://europepmc.org/articles/PMC9669181/
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 421 (2019)
Various glutamate urea ligands have displayed high affinities to prostate specific membrane antigen (PSMA), which is highly overexpressed in prostate and other cancer sites. The multivalent versions of small PSMA-targeted molecules are known to be ev
Externí odkaz:
https://doaj.org/article/f76f131d5a8f48b29249c4826fd6f202
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7160
We previously reported the design and synthesis of a small-molecule drug conjugate (SMDC) platform that demonstrated several advantages over antibody–drug conjugates (ADCs) in terms of in vivo pharmacokinetics, solid tumor penetration, definitive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991d41f0c4388a0b9713922a91fe2f84
Autor:
Joseph A. Frankl, Yu An, Amber Sherwood, Guiyang Hao, Feng-Yun Huang, Pawan Thapa, Deborah J. Clegg, Xiankai Sun, Philipp E. Scherer, Orhan K. Öz
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4880
Obesity is a leading cause of preventable death and morbidity. To elucidate the mechanisms connecting metabolically active brown adipose tissue (BAT) and metabolic health may provide insights into methods of treatment for obesity-related conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13eeaaa01a1f1264a92b22913a167c7