Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Guiyan Ni"'
Autor:
Yi Wang, Yao Jiang, Guiyan Ni, Shujuan Li, Brad Balderson, Quan Zou, Huatao Liu, Yifan Jiang, Jingchun Sun, Xiangdong Ding
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract The dermis and epidermis, crucial structural layers of the skin, encompass appendages, hair follicles (HFs), and intricate cellular heterogeneity. However, an integrated spatiotemporal transcriptomic atlas of embryonic skin has not yet been
Externí odkaz:
https://doaj.org/article/6e75bf7f44ce4ff8b92cd2acdc77d2b3
Autor:
Tuan Vo, Brad Balderson, Kahli Jones, Guiyan Ni, Joanna Crawford, Amanda Millar, Elissa Tolson, Matthew Singleton, Marija Kojic, Thomas Robertson, Shaun Walters, Onkar Mulay, Dharmesh D. Bhuva, Melissa J. Davis, Brandon J. Wainwright, Quan Nguyen, Laura A. Genovesi
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-28 (2023)
Abstract Background Medulloblastoma (MB) is a malignant tumour of the cerebellum which can be classified into four major subgroups based on gene expression and genomic features. Single-cell transcriptome studies have defined the cellular states under
Externí odkaz:
https://doaj.org/article/7b01e6e8430f4272932f8e0c58f61003
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Polygenic scores (PGS) are often based on GWAS data from individuals of European ancestry, thus limiting their use in populations of non-European ancestry. Here, the authors predict the relative accuracy of PGS across ancestries and suggest that caus
Externí odkaz:
https://doaj.org/article/8dac5eebf7ee40489c3b6857629f64e9
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Complex traits are often influenced by genetic and non-genetic factors (such as environmental exposures), which are themselves interconnected. Here, the authors develop a method for disentangling genotype–covariate correlation and interaction, and
Externí odkaz:
https://doaj.org/article/b73da63376ad4ac8b1df5ee607da5804
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Heterogeneity in the phenotypic mean and variance across populations is often observed for complex traits. One way to understand heterogeneous phenotypes lies in uncovering heterogeneity in genetic effects. Previous studies on genetic heterogeneity a
Externí odkaz:
https://doaj.org/article/20c29ba522164a74b9ba65c503e258bc
Autor:
Xuan Zhou, Julius van der Werf, Kristin Carson‐Chahhoud, Guiyan Ni, John McGrath, Elina Hyppönen, S. Hong Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
Background Both genetic and nongenetic factors can predispose individuals to cardiovascular risk. Finding ways to alter these predispositions is important for cardiovascular disease prevention. Methods and Results We used a novel whole‐genome appro
Externí odkaz:
https://doaj.org/article/bfcef8b5ba4540689f2593b43ced505b
Autor:
Guiyan Ni, Jacob Gratten, Naomi R. Wray, Sang Hong Lee, Schizophrenia Working Group of the Psychiatric Genomics Consortium
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genet
Externí odkaz:
https://doaj.org/article/b121f8fd81f84b068af22ae55cb96139
Autor:
Vo, Tuan, Balderson, Brad, Kahli Jones, Guiyan Ni, Crawford, Joanna, Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Kojic, Marija, Robertson, Thomas, Walters, Shaun, Mulay, Onkar, Dharmesh D. Bhuva, Davis, Melissa J., Wainwright, Brandon J., Nguyen, Quan, Genovesi, Laura A.
Medulloblastoma (MB) is a malignant tumour of the cerebellum which can be classified into four major subgroups based on gene expression and genomic features. Single cell transcriptome studies have defined the cellular states underlying each MB subgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534f258f5129c2e97abdf6ccdad854c1
Autor:
Duy Pham, Buu Truong, Khai Tran, Guiyan Ni, Dat Nguyen, Trang T H Tran, Mai H Tran, Duong Nguyen Thuy, Nam S Vo, Quan Nguyen
Publikováno v:
Briefings in Bioinformatics. 23
Most polygenic risk score (PRS)models have been based on data from populations of European origins (accounting for the majority of the large genomics datasets, e.g. >78% in the UK Biobank and >85% in the GTEx project). Although several large-scale As
Autor:
Dinesh Selvakumar, Zoe E. Clayton, Andrew Prowse, Steve Dingwall, Jacob George, Haisam Shah, Siqi Chen, Robert D. Hume, Laurentius Tjahjadi, Sindhu Igoor, Rhys J.P. Skelton, Alfred Hing, Hugh Paterson, Sheryl L. Foster, Lachlan Pearson, Emma Wilkie, Prajith Jeyaprakash, Zhixuan Wu, Jeffrey R. McArthur, Tony Barry, Juntang Lu, Vu Tran, Richard Bennett, Yasuhito Kotake, Timothy Campbell, Samual Turnbull, Quan Nguyen, Guiyan Ni, Stuart M. Grieve, Nathan J. Palpant, Faraz Pathan, Eddy Kizana, Saurabh Kumar, Peter P. Gray, James J.H. Chong
BackgroundExciting pre-clinical data have confirmed that human pluripotent stem cell derived cardiomyocytes (PSC-CMs) can remuscularise the injured or diseased heart, with several clinical trials now in planning or recruitment stages worldwide. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7f46d89844310efcbf9967fbd5495b
https://doi.org/10.1101/2022.09.15.500719
https://doi.org/10.1101/2022.09.15.500719