Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Guixiu SHI"'
Autor:
Hongyan Qian, Chaoqiong Deng, Shiju Chen, Xinwei Zhang, Yan He, Jingying Lan, Aodi Wang, Guixiu Shi, Yuan Liu
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Fibroblast-like synoviocytes (FLSs) play a central role in RA pathogenesis and are the main cellular component in the inflamed synovium of patients with rheumatoid arthritis (RA). FLSs are emerging as promising new therapeutic targets in RA.
Externí odkaz:
https://doaj.org/article/2d84afc23e65472eb712edf206e496aa
Autor:
Jingying Lan, Chaoqiong Deng, Heqing Huang, Peishi Rao, Yangchun Chen, Yingying Shi, Jie Chen, Guixiu Shi, Yuan Liu, Shiju Chen
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Background To investigate the clinical and immune characteristics of patients with primary Sjögren’s syndrome (pSS) who were negative for anti–Sjögren’s-syndrome-related antigen A antibodies (anti-SSA) and anti–Sjögren’s-syndrom
Externí odkaz:
https://doaj.org/article/4acc410cffeb48078f62147278578b7d
Autor:
Lu Zhang, Yan He, Mengqin Zhang, Jimin Zhang, Wuwei Zhuang, Yuechi Sun, Xing Chen, Hangzhou Fu, Xuanli Tang, Guixiu Shi
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110350- (2024)
Summary: Lupus nephritis (LN), a severe complication of systemic lupus erythematosus (SLE), exhibits significant heterogeneity. Recent evidence suggests that non-immune factors contribute to end-organ damage, challenging the traditional view of LN so
Externí odkaz:
https://doaj.org/article/27f9229b71714187b24711a578559c87
Autor:
Yun Peng, Yuanhui Wu, Shiju Chen, Yuan Liu, Hongyan Qian, Yan He, Heqing Huang, Meimei Cai, Wen Liu, Guixiu Shi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Microdamage and its related inflammation contribute to the development of radiographic axial spondyloarthritis (r-axSpA). Inflammation and cell death in damaged tissues are associated with cell-free DNA (cfDNA) release. Here we investigated
Externí odkaz:
https://doaj.org/article/05801348bf7941aaa6a013c26a21fa9e
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-7 (2022)
Abstract Introduction The autoimmune exocrinopathy, Sjögren’s syndrome (SjS), is associated with secretory defects in salivary glands. The cystic fibrosis transmembrane conductance regulator (CFTR) of the chloride channel is a master regulator of
Externí odkaz:
https://doaj.org/article/0a578bd4c3724cd893de149444975769
Autor:
Yufei Jiang, Yan He, Songting Liu, Gaizhen Li, Dunjin Chen, Wenbo Deng, Ping Li, Ying Zhang, Jinxiang Wu, Jianing Li, Longmei Wang, Jiajing Lin, Haibin Wang, Shuangbo Kong, Guixiu Shi
Publikováno v:
eLife, Vol 12 (2023)
Decidualization, denoting the transformation of endometrial stromal cells into specialized decidual cells, is a prerequisite for normal embryo implantation and a successful pregnancy in human. Here, we demonstrated that knockout of Gαq lead to an ab
Externí odkaz:
https://doaj.org/article/3b71c68374504af9a19850bf1d9cd595
Autor:
Xinwei Zhang, Hongyan Qian, Yangchun Chen, Yuanhui Wu, Yuechi Sun, Yan He, Shiju Chen, Guixiu Shi, Yuan Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/340a32326a6a4c70a79162963291e72e
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Objectives To investigate longitudinal relationship between serum uric acid (SUA) and disease activity among Chinese males with axial spondyloarthritis (axSpA). Methods Two-year data from the NASA study cohort of male patients with axial spo
Externí odkaz:
https://doaj.org/article/60937392de1e413388a3eb5826917580
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Objectives The pathological diagnostic criteria for primary Sjögren’s syndrome (SjS) have certain limitations. We first explored the key pathogenic pathways of SjS through a bioinformatics approach, and then evaluated the diagnostic value of the i
Externí odkaz:
https://doaj.org/article/ec5e8b9731024653896f42401514c456
Autor:
Yuan Liu, Peishi Rao, Hongyan Qian, Yesi Shi, Shiju Chen, Jingying Lan, Dan Mu, Rongjuan Chen, Xinwei Zhang, Chaoqiong Deng, Gang Liu, Guixiu Shi
Publikováno v:
Advanced Science, Vol 10, Iss 4, Pp n/a-n/a (2023)
Abstract Fibroblast‐like synoviocytes (FLS) are the main cell component in the inflamed joints of patients with rheumatoid arthritis (RA). FLS intimately interact with infiltrating T cells. Fibroblasts have potent inhibitory effects on T cells, lea
Externí odkaz:
https://doaj.org/article/da0eb49dc28e45929f0eb52afd5c8b81