Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Guislaine Refrégier"'
Autor:
Christophe Guyeux, Gaetan Senelle, Adrien Le Meur, Philip Supply, Cyril Gaudin, Jody E. Phelan, Taane G Clark, Leen Rigouts, Bouke de Jong, Christophe Sola, Guislaine Refrégier
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 3, Pp 560-563 (2024)
Analysis of genome sequencing data from >100,000 genomes of Mycobacterium tuberculosis complex using TB-Annotator software revealed a previously unknown lineage, proposed name L10, in central Africa. Phylogenetic reconstruction suggests L10 could rep
Externí odkaz:
https://doaj.org/article/d09a336b2efc4edf9d42a226f05ad04f
Autor:
Gary Napier, David Couvin, Guislaine Refrégier, Christophe Guyeux, Conor J. Meehan, Christophe Sola, Susana Campino, Jody Phelan, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Bacterial strain-types in the Mycobacterium tuberculosis complex underlie tuberculosis disease, and have been associated with drug resistance, transmissibility, virulence, and host–pathogen interactions. Spoligotyping was developed as a mo
Externí odkaz:
https://doaj.org/article/fcafc4a52ea941b0a4dbdda8c79a94e7
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-12 (2023)
Abstract Clustered Regularly Interspaced Short Palindromic repeats (CRISPR)-Cas systems rapidly raised from a bacterial genetic curiosity to the most popular tool for genetic modifications which revolutionized the study of microbial physiology. Due t
Externí odkaz:
https://doaj.org/article/9f5fd8d4eb0440cdbfb1fb9714454a32
Autor:
Charlotte Genestet, Guislaine Refrégier, Elisabeth Hodille, Rima Zein-Eddine, Adrien Le Meur, Fiona Hak, Alexia Barbry, Emilie Westeel, Jean-Luc Berland, Astrid Engelmann, Isabelle Verdier, Gérard Lina, Florence Ader, Stéphane Dray, Laurent Jacob, François Massol, Samuel Venner, Oana Dumitrescu
Publikováno v:
International Journal of Infectious Diseases, Vol 125, Iss , Pp 74-83 (2022)
ABSTRACT: Objectives: Mycobacterium tuberculosis (Mtb) infections result in a wide spectrum of clinical presentations but without proven Mtb genetic determinants. Herein, we hypothesized that the genetic features of Mtb clinical isolates, such as spe
Externí odkaz:
https://doaj.org/article/3131c6b37e154dc0ae4667bf1158cc63
Autor:
Charlotte Genestet, Elisabeth Hodille, Albin Bernard, Maxime Vallée, Gérard Lina, Adrien Le Meur, Guislaine Refrégier, Oana Dumitrescua
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT To tackle the spread of tuberculosis (TB), epidemiological studies are undertaken worldwide to investigate TB transmission chains. Clustered regulatory interspaced short palindromic repeats (CRISPR) locus diversity, also called spoligotyping
Externí odkaz:
https://doaj.org/article/80de298ae99e4b93bdbf82c0c9e8693d
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Diversity of the CRISPR locus of Mycobacterium tuberculosis complex has been studied since 1997 for molecular epidemiology purposes. By targeting solely the 43 spacers present in the two first sequenced genomes (H37Rv and BCG), it
Externí odkaz:
https://doaj.org/article/08a9aa0a0d854af991d257972e8118c1
Publikováno v:
Microorganisms, Vol 10, Iss 8, p 1492 (2022)
As highlighted by the SARS pandemic which is still ongoing, the battle against pathogens relies on three main “weapons”: hygiene, vaccine development and chemotherapy strategies [...]
Externí odkaz:
https://doaj.org/article/d70dd71f47804873b275d504e623565b
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008500 (2021)
Mycobacterium tuberculosis complex (MTC) CRISPR locus diversity has long been studied solely investigating the presence/absence of a known set of spacers. Unveiling the genetic mechanisms of its evolution requires a more exhaustive reconstruction in
Externí odkaz:
https://doaj.org/article/df0ee078515645ad93ca1585ea88a301
Autor:
Emilyn Costa Conceição, Richard Steiner Salvato, Karen Machado Gomes, Arthur Emil dos Santos Guimarães, Marília Lima da Conceição, Ricardo José de Paula Souza e Guimarães, Abhinav Sharma, Ismari Perini Furlaneto, Regina Bones Barcellos, Valdes Roberto Bollela, Lívia Maria Pala Anselmo, Maria Carolina Sisco, Cristina Viana Niero, Lucilaine Ferrazoli, Guislaine Refrégier, Maria Cristina da Silva Lourenço, Harrison Magdinier Gomes, Artemir Coelho de Brito, Marcos Catanho, Rafael Silva Duarte, Philip Noel Suffys, Karla Valéria Batista Lima
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 116 (2021)
Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies published from 1996-2019 was p
Externí odkaz:
https://doaj.org/article/875b89d9ecac468d95808517a10a9444
Autor:
Noël Harijaona Ratovonirina, Niaina Rakotosamimanana, Solohery Lalaina Razafimahatratra, Mamy Serge Raherison, Guislaine Refrégier, Christophe Sola, Fanjasoa Rakotomanana, Voahangy Rasolofo Razanamparany
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Tuberculosis (TB) remains a public health problem in Madagascar. A crucial element of TB control is the development of an easy and rapid method for the orientation of TB control strategies in the country. Our main objective was to
Externí odkaz:
https://doaj.org/article/225a8398a07a41b3ac280d187859c059