Lipidomic changes in a novel sepsis outcome-based analysis reveals potent pro-inflammatory and pro-resolving signaling lipids.

Autor: Sulaiman D; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA., Wu D; Department of Biostatistics, University of Florida, Gainesville, Florida, USA., Black LP; Department of Emergency Medicine, Northwestern University, Chicago, IL, USA., Williams KJ; Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.; UCLA Lipidomics Lab, Los Angeles, California, USA., Graim K; Computer and Information Science and Engineering, University of Florida, Gainesville, Florida, USA., Datta S; Department of Biostatistics, University of Florida, Gainesville, Florida, USA., Reddy ST; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA., Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13745.

Racial disparities in septic shock mortality: a retrospective cohort study.

Autor: Black LP; Department of Emergency Medicine, Northwestern University, Feinberg School of Medicine, 211 Ontario Street, Suite 200, Chicago, IL, 60611, USA., Hopson C; Department of Emergency Medicine, University of Florida College of Medicine, 1329 SW 16th St, Suite 5270, Gainesville, FL, 32603, USA., Puskarich MA; Department of Emergency Medicine, Hennepin Healthcare, 701 Park Avenue, Minneapolis, MN, 55415, USA., Modave F; Department of Anesthesiology, University of Florida College of Medicine, 1600 SW Archer Rd, Gainesville, FL, 32610, USA., Booker SQ; Department of Biobehavioral Nursing Science, University of Florida College of Nursing, 1225 Center Dr, Gainesville, FL, 32610, USA., DeVos E; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street Jacksonville, FL, 32207, USA., Fernandez R; Department of Emergency Medicine, University of Florida College of Medicine, 1329 SW 16th St, Suite 5270, Gainesville, FL, 32603, USA., Garvan C; Department of Anesthesiology, University of Florida College of Medicine, 1600 SW Archer Rd, Gainesville, FL, 32610, USA., Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine, 1329 SW 16th St, Suite 5270, Gainesville, FL, 32603, USA.

Publikováno v: Lancet regional health. Americas [Lancet Reg Health Am] 2023 Dec 12; Vol. 29, pp. 100646. Date of Electronic Publication: 2023 Dec 12 (Print Publication: 2024).

Association Between Hypocholesterolemia and Mortality in Critically Ill Patients With Sepsis: A Systematic Review and Meta-Analysis.

Autor: Hofmaenner DA; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom.; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Arina P; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Kleyman A; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Page Black L; Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL., Salomao R; Division of Infectious Diseases, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, São Paulo, Brazil., Tanaka S; Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Anesthesiology and Critical Care Medicine, DMU PARABOL, Bichat-Claude Bernard Hospital, Paris, France.; French Institute of Health and Medical Research (INSERM), U1188 Diabetes Atherothrombosis Réunion Indian Ocean (DéTROI), CYROI Plateform, Réunion Island University, Saint-Denis de La Réunion, France., Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL., Arulkumaran N; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Singer M; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom.

Publikováno v: Critical care explorations [Crit Care Explor] 2023 Feb 01; Vol. 5 (2), pp. e0860. Date of Electronic Publication: 2023 Feb 01 (Print Publication: 2023).

Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.

Autor: Puskarich MA; Department of Emergency Medicine, University of Minnesota, Minneapolis.; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota., Ingraham NE; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis., Merck LH; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville., Driver BE; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota., Wacker DA; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis., Black LP; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville., Jones AE; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson., Fletcher CV; Center for Drug Discovery, University of Nebraska Medical Center, Omaha., South AM; Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, Winston Salem, North Carolina.; Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina.; Department of Surgery-Hypertension and Vascular Research, Wake Forest School of Medicine, Winston Salem, North Carolina., Murray TA; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Lewandowski C; Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, Michigan., Farhat J; Department of Surgery, North Memorial Medical Center, Minneapolis, Minnesota., Benoit JL; Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio., Biros MH; Department of Emergency Medicine, University of Minnesota, Minneapolis., Cherabuddi K; Department of Emergency Medicine, University of Florida College of Medicine, Gainesville., Chipman JG; Department of Surgery, University of Minnesota, Minneapolis., Schacker TW; Division of Infectious Disease, Department of Medicine, University of Minnesota, Minneapolis., Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine, Jacksonville., Voelker HT; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Koopmeiners JS; Department of Biostatistics, School of Public Health, University of Minnesota, Minneapolis., Tignanelli CJ; Department of Surgery, University of Minnesota, Minneapolis.

Publikováno v: JAMA network open [JAMA Netw Open] 2022 Mar 01; Vol. 5 (3), pp. e222735. Date of Electronic Publication: 2022 Mar 01.

A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes.

Autor: Guirgis FW; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA. Faheem.Guirgis@jax.ufl.edu., Black LP; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Henson M; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Labilloy G; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA., Smotherman C; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA., Hopson C; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA., Tfirn I; Center for Data Solutions, University of Florida College of Medicine - Jacksonville, Jacksonville, FL, USA., DeVos EL; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Leeuwenburgh C; Department of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, FL, USA., Moldawer L; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Datta S; Department of Biostatistics, University of Florida, Gainesville, FL, USA., Brusko TM; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL, USA.; Department of Pediatrics, University of Florida Diabetes Institute, College of Medicine, Gainesville, FL, USA., Hester A; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Bertrand A; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Grijalva V; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Arango-Esterhay A; Department of Emergency Medicine, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA., Moore FA; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Reddy ST; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Publikováno v: Critical care (London, England) [Crit Care] 2021 Sep 17; Vol. 25 (1), pp. 341. Date of Electronic Publication: 2021 Sep 17.