Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Guiqiong, He"'
Publikováno v:
Genes and Diseases, Vol 11, Iss 5, Pp 101125- (2024)
Externí odkaz:
https://doaj.org/article/7856ea40729e48ad963c13728a46de1e
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 1, Pp 165-177 (2024)
Long non-coding RNAs (lncRNAs) have attracted significant scientific attention due to their central role in regulating gene expression and their profound impact on the intricate mechanisms of ovarian function. These versatile molecules exert their in
Externí odkaz:
https://doaj.org/article/06878ff482f74930bcce6104eeb87eb5
Autor:
Man Luo, Yayan Pang, Junjie Li, Lilin Yi, Bin Wu, Qiuyun Tian, Yan He, Maoju Wang, Lei Xia, Guiqiong He, Weihong Song, Yehong Du, Zhifang Dong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 635-652 (2024)
Alzheimer's disease (AD) is a leading cause of dementia in the elderly. Mitogen-activated protein kinase phosphatase 1 (MKP-1) plays a neuroprotective role in AD. However, the molecular mechanisms underlying the effects of MKP-1 on AD have not been e
Externí odkaz:
https://doaj.org/article/3c74df04a92a4e7c9d31b5922b70dbad
Publikováno v:
Biomolecules & Biomedicine (2024)
Neuropathic pain (NPP) remains a clinically challenging condition, driven by the activation of spinal astrocytes and the complex release of inflammatory mediators. This study aimed to examine the roles of Rab8a and SNARE complex proteins in activated
Externí odkaz:
https://doaj.org/article/8f033678cd4d4152aeb88dc205332ed3
Publikováno v:
Genes and Diseases, Vol 10, Iss 5, Pp 1908-1919 (2023)
Neurexin-3 is primarily localized in the presynaptic membrane and forms complexes with various ligands located in the postsynaptic membrane. Neurexin-3 has important roles in synapse development and synapse functions. Neurexin-3 mediates excitatory p
Externí odkaz:
https://doaj.org/article/2651b487afaf4845b6f226c4ff6e61be
Autor:
Yu Qiu, Yueyang Zhao, Zhimin Long, Aijia Song, Peng Huang, Kejian Wang, Ling Xu, David Paul Molloy, Guiqiong He
Publikováno v:
Genes and Diseases, Vol 10, Iss 1, Pp 284-300 (2023)
Osteoporosis (OP) is a debilitating skeletal abnormality involving bone remodeling and bone cell homeostasis characterized by decreased bone strength and high fracture risk. A novel therapeutic intervention for OP by manipulating cellular autophagy
Externí odkaz:
https://doaj.org/article/d5ec4adb654c40c1b38b85bf3031ea88
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2023)
IntroductionProtein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 (POMGNT1) is crucial for the elongation of O-mannosyl glycans. Mutations in POMGNT1 cause muscle-eye-brain (MEB) disease, one of the main features of which is anatomical abe
Externí odkaz:
https://doaj.org/article/1b3190bf5b04429484197f6469e4f20d
Autor:
Deivid Carvalho Rodrigues, Emily M. Harvey, Rejitha Suraj, Sarah L. Erickson, Lamees Mohammad, Mengli Ren, Hongrui Liu, Guiqiong He, David R. Kaplan, James Ellis, Guang Yang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Gene regulation and metabolism co-ordinate self-renewal and differentiation of neural precursors (NPCs) in the developing brain. Here the authors show that methylglyoxal, a glycolytic intermediate metabolite, promotes GADPH-dependent translational re
Externí odkaz:
https://doaj.org/article/5de70668dec54528b947cdd22f16d0df
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Allergic asthma is a typical chronic inflammatory disease of respiratory tract. Clinical data shows that patients with allergic asthma have different degrees of cognitive dysfunction. The molecular mechanism underlying the pathogenesis of asthma-indu
Externí odkaz:
https://doaj.org/article/ad2b601ffaf94725b69b289d5091db73
Autor:
Peng Huang, David Paul Molloy, Zhimin Long, Yueyang Zhao, Aijia Song, Ling Xu, Kejian Wang, Yu Qiu, Guiqiong He
Publikováno v:
Genes Dis
Osteoporosis (OP) is a debilitating skeletal abnormality involving bone remodeling and bone cell homeostasis characterized by decreased bone strength and high fracture risk. A novel therapeutic intervention for OP by manipulating cellular autophagy