Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Guiqian Chen"'
Autor:
Salma Nassor Juma, Junguang Liao, Yuping Huang, Rexhina Vlashi, Qingwan Wang, Bocong Wu, Dan Wang, Mengrui Wu, Guiqian Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 100986- (2024)
Osteoarthritis and psoriasis arthritis are two degenerative forms of arthritis that share similar yet also different manifestations at the histological, cellular, and clinical levels. Rheumatologists have marked them as two entirely distinct arthropa
Externí odkaz:
https://doaj.org/article/908f452466fd47a6b6268d4e5c1e9bd9
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1291-1317 (2023)
Wnt signaling executes an indispensable performance in osteoblast differentiation, bone development, homeostasis, and remodeling. Wnt signals trigger the intracellular Wnt signaling cascade to initiate regulating the implication of β-catenin in the
Externí odkaz:
https://doaj.org/article/6a792f5bea9846349ae712f836d87be8
Autor:
Lei Wang, Meng Xu, Haofeng Hu, Lun Zhang, Fei Ye, Jia Jin, Hongming Fang, Jian Chen, Guiqian Chen, Sylvain Broussy, Michel Vidal, Zhengbing Lv, Wang-Qing Liu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pathological angiogenesis is mainly initiated by the binding of abnormal expressed vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs). Blocking the VEGF/VEGFR interaction is a clinically proven treatment in cancer. Our previous w
Externí odkaz:
https://doaj.org/article/9e4e84a1bf25487783ae4d1808b1686c
Autor:
Wenjie Zhang, Ping Qin, Xiaoxia Gong, Lei Huang, Chan Wang, Guiqian Chen, Jianqing Chen, Lei Wang, Zhengbing Lv
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Whitespotted bamboo shark (Chiloscyllium plagiosum), a member of the cartilaginous fish family, has an extremely large liver and demonstrates a strong regeneration ability and immune regulation. Circular RNAs (circRNAs) is an important class of non-c
Externí odkaz:
https://doaj.org/article/ad01b5bfa4634d0ca18069c59a7df546
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Strategies for treating brain metastases of breast cancer have demonstrated limited efficacy due to the blood–brain barrier (BBB). Gene therapy could improve the efficacy of chemotherapeutic drugs. Exosomes derived from the mesenchymal stem cells (
Externí odkaz:
https://doaj.org/article/f96146122a6448ed902147ce89d61f88
Autor:
Guiqian Chen, Haodong Xu, Yifeng Yao, Tingting Xu, Mengting Yuan, Xingen Zhang, Zhengbing Lv, Mengrui Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The bone morphogenetic protein (BMP) signaling pathway is highly conserved across many species, and its importance for the patterning of the skeletal system has been demonstrated. A disrupted BMP signaling pathway results in severe skeletal defects.
Externí odkaz:
https://doaj.org/article/3186cb9a9aee4a9aa281a418817d2e6d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 6, Pp 2525-2534 (2017)
Background/Aims: The mammalian skull vault is a highly regulated structure and consists of several membrane bones of different tissue origins (e.g. neural crest derived frontal bone and mesoderm derived parietal bone). Although membrane bones form th
Externí odkaz:
https://doaj.org/article/aa1bda9db50c446692056ae2a8f4d1d4
Shark New Antigen Receptor (IgNAR): Structure, Characteristics and Potential Biomedical Applications
Autor:
Salma Nassor Juma, Xiaoxia Gong, Sujie Hu, Zhengbing Lv, Jianzhong Shao, Lili Liu, Guiqian Chen
Publikováno v:
Cells, Vol 10, Iss 5, p 1140 (2021)
Shark is a cartilaginous fish that produces new antigen receptor (IgNAR) antibodies. This antibody is identified with a similar human heavy chain but dissimilar sequences. The variable domain (VNAR) of IgNAR is stable and small in size, these feature
Externí odkaz:
https://doaj.org/article/d70ab9487cec49349247c84323964d97
Autor:
Yongxia Zheng, Huan Chen, Manxiang Yin, Xiaoqian Ye, Guiqian Chen, Xinmei Zhou, Lei Yin, Chengwen Zhang, Baoyue Ding
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 2, Pp 729-739 (2015)
Background/Aims: Our previous study has demonstrated that down-regulation of miR-376a might contribute to the development of hepatocellular carcinoma (HCC), but the mechanism underlying this down-regulation remains obscure. Methods/Results: histone d
Externí odkaz:
https://doaj.org/article/7c4bbc4b83c149af976ef07a688cb082
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153342 (2016)
Neuropeptide Y (NPY) is one of the most potent stimulants of food intake in many animals. Most of the supporting evidence for the effects of NPY has been gathered in mammalian species using porcine NPY. To investigate the effects of NPY on precocial
Externí odkaz:
https://doaj.org/article/a23f40d3807b4f5d980a862b74f2922a