Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Guiomar, Solanas"'
Publikováno v:
Translational Medicine of Aging, Vol 6, Iss , Pp 1-13 (2022)
Circadian rhythms provide temporal variation of a broad range of behavioral and physiological functions, which is precisely controlled by the internal molecular gear, the circadian clock. However, circadian clock functions decline concomitantly with
Externí odkaz:
https://doaj.org/article/531cd815a9f04ec4ab46c4d02f23a60e
Autor:
Chen Yuan Kam, Ishani D. Singh, Catherine Matte-Martone, David G. Gonzalez, Paloma Solá, Guiomar Solanas, Júlia Bonjoch, Edward D. Marsh, Karen K. Hirschi, Valentina Greco
A functional network of blood vessels is essential for organ growth and homeostasis. Yet, how the vasculature matures and maintains adult homeostasis remains elusive in live mice. By longitudinally tracking the same neonatal endothelial cells (ECs) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7552a4f64b97c20025b9309d7bbcbd77
https://doi.org/10.1101/2022.11.02.514907
https://doi.org/10.1101/2022.11.02.514907
Autor:
Lorenzo Rinaldi, Alexandra Avgustinova, Mercè Martín, Debayan Datta, Guiomar Solanas, Neus Prats, Salvador Aznar Benitah
Publikováno v:
eLife, Vol 6 (2017)
The DNA methyltransferase Dnmt3a suppresses tumorigenesis in models of leukemia and lung cancer. Conversely, deregulation of Dnmt3b is thought to generally promote tumorigenesis. However, the role of Dnmt3a and Dnmt3b in many types of cancer remains
Externí odkaz:
https://doaj.org/article/cf07f708e0b14e68abffb01ba391d133
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice
Autor:
Chen Yuan Kam, Ishani D. Singh, David G. Gonzalez, Catherine Matte-Martone, Paloma Solá, Guiomar Solanas, Júlia Bonjoch, Edward Marsh, Karen K. Hirschi, Valentina Greco
Publikováno v:
Cell. 186:2345-2360.e16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79480c6f67c917d06748f9560d70190a
https://doi.org/10.1016/j.cell.2023.04.017
https://doi.org/10.1016/j.cell.2023.04.017
Autor:
Paloma Solá, Elisabetta Mereu, Júlia Bonjoch, Marta Casado, Oscar Reina, Enrique Blanco, Manel Esteller, Luciano DiCroce, Holger Heyn, Guiomar Solanas, Salvador Aznar Benitah
Skin aging is characterized by structural and functional changes that lead to slower wound healing and higher rate of infections, which contribute to age-associated frailty. This likely depends on synergy between alterations in the local microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b102efee08f9f2d64b8e8db1fe4aa8c
https://doi.org/10.1101/2022.01.31.478459
https://doi.org/10.1101/2022.01.31.478459
Autor:
Iván Ballesteros, Andrea Rubio-Ponce, Salvador Aznar Benitah, Andrés Hidalgo, Juan A. Quintana, Guiomar Solanas, Fátima Sánchez-Cabo
Publikováno v:
NAR Genomics and Bioinformatics
Circadian-regulated genes are essential for tissue homeostasis and organismal function, and are therefore common targets of scrutiny. Detection of rhythmic genes using current analytical tools requires exhaustive sampling, a demand that is costly and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91c1eca88e2babd00b91ec267aae25f
https://doi.org/10.1093/nargab/lqab031
https://doi.org/10.1093/nargab/lqab031
Publikováno v:
Nature. 574:337-338
The body’s circadian clock ensures the rhythmic expression of some genes across the day. The catalogue of genes under circadian control changes in an aggressive brain cancer — a discovery that might open up a new avenue for treatment. Glioblastom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eed1a1b2ebba247c89103800b432472
https://doi.org/10.1038/d41586-019-03042-0
https://doi.org/10.1038/d41586-019-03042-0
Autor:
Ana Corrionero, Imma Raurell, Antonio García de Herreros, David Casagolda, Susana Miravet, Julio Castaño, Mireia Duñach, Guiomar Solanas
Publikováno v:
Journal of Biological Chemistry. 291:23925-23927
beta-Catenin and plakoglobin are related proteins involved in the regulation of adherens junctions and desmosomes. Moreover, by binding to Tcf-4, they can act as transcriptional modulators of genes involved in embryonic development and tumorigenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d727a8171ff38a47dbc5ae5bf473e86
https://doi.org/10.1074/jbc.a116.408685
https://doi.org/10.1074/jbc.a116.408685
Autor:
Mercè Martín, Salvador Aznar Benitah, Neus Prats, Debayan Datta, Alexandra Avgustinova, Lorenzo Rinaldi, Guiomar Solanas
Publikováno v:
eLife
Recercat. Dipósit de la Recerca de Catalunya
instname
eLife, Vol 6 (2017)
Recercat. Dipósit de la Recerca de Catalunya
instname
eLife, Vol 6 (2017)
The DNA methyltransferase Dnmt3a suppresses tumorigenesis in models of leukemia and lung cancer. Conversely, deregulation of Dnmt3b is thought to generally promote tumorigenesis. However, the role of Dnmt3a and Dnmt3b in many types of cancer remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca069610cf7bd50a9323286b37ea7071
https://doi.org/10.7554/elife.21697
https://doi.org/10.7554/elife.21697