Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface

Autor: O'Neill, P, Lindsay, SL, Pantiru, A, Guimond, SE, Fagoe, N, Verhaagen, J, Turnbull, JE, Riddell, JS, Barnett, SC

Publikováno v: Glia

Schwann cell (SC) transplantation following spinal cord injury (SCI) may have therapeutic potential. Functional recovery is limited however, due to poor SC interactions with host astrocytes and the induction of astrogliosis. Olfactory ensheathing cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1c1869e0fd0db5757d8a4612b045581a
http://europepmc.org/articles/PMC5244676

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High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts.

Autor: Maciej-Hulme ML; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk., Leprince ACN; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk.; Université de Rennes 1, Rue du Thabor, 35065 Rennes Cedex, France., Lavin A; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK., Guimond SE; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk., Turnbull JE; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk., Pelletier J; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk., Yates EA; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK., Powell AK; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK., Skidmore MA; Centre for Glycoscience Research and Training, School of Life Sciences, Keele University, Staffordshire, ST5 5BG, UK. m.a.skidmore@keele.ac.uk.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.

Publikováno v: Analytical methods : advancing methods and applications [Anal Methods] 2023 Mar 16; Vol. 15 (11), pp. 1461-1469. Date of Electronic Publication: 2023 Mar 16.

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction.

Autor: Guimond SE; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire ST5 5BG, United Kingdom., Mycroft-West CJ; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire ST5 5BG, United Kingdom., Gandhi NS; School of Chemistry and Physics, Centre for Genomics and Personalized Health, Queensland University of Technology, 2 George Street, Brisbane, Queensland 4000, Australia., Tree JA; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom., Le TT; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Spalluto CM; School of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton SO17 1BJ, United Kingdom., Humbert MV; School of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton SO17 1BJ, United Kingdom., Buttigieg KR; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom., Coombes N; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom., Elmore MJ; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom., Wand M; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom., Nyström K; Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Guldhedsgatan 10B, S-413 46 Goteborg, Sweden., Said J; Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Guldhedsgatan 10B, S-413 46 Goteborg, Sweden., Setoh YX; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Amarilla AA; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Modhiran N; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Sng JDJ; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Chhabra M; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Young PR; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Rawle DJ; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Lima MA; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire ST5 5BG, United Kingdom., Yates EA; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom., Karlsson R; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark., Miller RL; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark., Chen YH; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark., Bagdonaite I; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark., Yang Z; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark., Stewart J; Department of Infection Biology & Microbiomes, University of Liverpool, Liverpool L69 7ZB, United Kingdom., Nguyen D; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, Oxford University, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom., Laidlaw S; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, Oxford University, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom., Hammond E; Zucero Therapeutics Ltd, 1 Westlink Court, Brisbane, Queensland 4076, Australia., Dredge K; Zucero Therapeutics Ltd, 1 Westlink Court, Brisbane, Queensland 4076, Australia., Wilkinson TMA; School of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton SO17 1BJ, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton SO16 6YD, United Kingdom., Watterson D; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Khromykh AA; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Suhrbier A; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Carroll MW; National Infection Service, UK Health Security Agency, Porton Down, Salisbury, Wiltshire SP4 0JG, United Kingdom.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, Oxford University, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom., Trybala E; Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Guldhedsgatan 10B, S-413 46 Goteborg, Sweden., Bergström T; Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Guldhedsgatan 10B, S-413 46 Goteborg, Sweden., Ferro V; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.; Australian Infectious Diseases Research Centre, GVN Center of Excellence, Brisbane, Queensland 4072/4079, Australia., Skidmore MA; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire ST5 5BG, United Kingdom., Turnbull JE; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire ST5 5BG, United Kingdom.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen N 2200, Denmark.

Publikováno v: ACS central science [ACS Cent Sci] 2022 May 25; Vol. 8 (5), pp. 527-545. Date of Electronic Publication: 2022 Mar 29.