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Pharmacokinetic variability of CFTR modulators from standard and alternative regimens.

Autor: Rose NR; Department of Pediatrics, Division of Pulmonary and Sleep Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; Gregory Fleming James Cystic Fibrosis Research Center, UAB, Birmingham, AL, USA., Chalamalla AR; Department of Pediatrics, Division of Pulmonary and Sleep Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; Gregory Fleming James Cystic Fibrosis Research Center, UAB, Birmingham, AL, USA., Garcia BA; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, UAB, Birmingham, AL, USA., Krick S; Gregory Fleming James Cystic Fibrosis Research Center, UAB, Birmingham, AL, USA; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, UAB, Birmingham, AL, USA., Bergeron J; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, UAB, Birmingham, AL, USA., Sadeghi H; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA., Schellhase DE; Department of Pediatrics, Division of Pulmonary and Sleep Medicine, Atrium Health Levine Children's Specialty Center, Charlotte, NC, USA., Ryan KJ; Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, UAB, Birmingham, AL, USA., Dowell AE; Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, UAB, Birmingham, AL, USA., Acosta EP; Gregory Fleming James Cystic Fibrosis Research Center, UAB, Birmingham, AL, USA; Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, UAB, Birmingham, AL, USA., Guimbellot JS; Department of Pediatrics, Division of Pulmonary and Sleep Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA; Gregory Fleming James Cystic Fibrosis Research Center, UAB, Birmingham, AL, USA; Department of Pediatrics, Section of Pulmonary and Sleep Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address: jguimbellot@uams.edu.

Publikováno v: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2024 Sep; Vol. 86, pp. 102301. Date of Electronic Publication: 2024 May 24.

Differential distribution of ivacaftor and its metabolites in plasma and human airway epithelia.

Autor: Liu Z; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Anderson JD; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Rose NR; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Baker EH; Department of Sociology, University of Alabama at Birmingham, Birmingham, AL, USA., Dowell AE; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA., Ryan KJ; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA., Acosta EP; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA., Guimbellot JS; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address: jguimbellot@uams.edu.

Publikováno v: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2024 Sep; Vol. 86, pp. 102314. Date of Electronic Publication: 2024 Jul 02.

Mobile health platform for self-management of pediatric cystic fibrosis: Impact on patient-centered care outcomes.

Autor: Oates GR; Pediatric Pulmonary and Sleep Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: goates@uabmc.edu., Mims C; Children's of Alabama, Birmingham, AL, USA., Geurs R; Pediatric Pulmonary and Sleep Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bergquist R; Motivo Management, LLC, Reno, NV, USA; Upstream Dream AB, Stockholm, Sweden., Hager A; Upstream Dream AB, Stockholm, Sweden., Guimbellot JS; Pediatric Pulmonary and Sleep Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Hartzes AM; School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Gutierrez HH; Pediatric Pulmonary and Sleep Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Publikováno v: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2023 Sep; Vol. 22 (5), pp. 823-829. Date of Electronic Publication: 2023 Apr 19.

Pharmacogenetic actionability and medication prescribing in people with cystic fibrosis.

Autor: Anderson JD; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA., Davis BH; Department of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Giang G; McWhorter School of Pharmacy, Samford University, Birmingham, Alabama, USA., Jones A; McWhorter School of Pharmacy, Samford University, Birmingham, Alabama, USA., Lee CR; McWhorter School of Pharmacy, Samford University, Birmingham, Alabama, USA., Parker K; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA., Searcy H; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA., Benner K; McWhorter School of Pharmacy, Samford University, Birmingham, Alabama, USA., Limdi NA; Department of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Guimbellot JS; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2023 Apr; Vol. 16 (4), pp. 662-672. Date of Electronic Publication: 2023 Feb 09.