Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19: The TOGETHER Randomized Clinical Trial.

Autor: Reis G; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil.; Department of Medicine, Pontifícia Universidade Católica de Minas Gerais, Brazil., Moreira Silva EADS; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil.; Department of Medicine, Pontifícia Universidade Católica de Minas Gerais, Brazil., Medeiros Silva DC; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil.; Department of Medicine, Pontifícia Universidade Católica de Minas Gerais, Brazil., Thabane L; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Singh G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Park JJH; Experimental Medicine, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.; Cytel Inc, Vancouver, British Columbia, Canada., Forrest JI; Experimental Medicine, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.; Cytel Inc, Vancouver, British Columbia, Canada., Harari O; Cytel Inc, Vancouver, British Columbia, Canada., Quirino Dos Santos CV; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil.; Department of Medicine, Pontifícia Universidade Católica de Minas Gerais, Brazil., Guimarães de Almeida APF; Department of Public Health, Montes Claros State University, Montes Claros, Brazil., Figueiredo Neto AD; Public Health Fellowship Program, Governador Valadares Public Health Authority, Brazil., Savassi LCM; Public Health, Mental and Family Medicine Department, Ouro Preto Federal University, Ouro Preto, Brazil., Milagres AC; Public Health, Mental and Family Medicine Department, Ouro Preto Federal University, Ouro Preto, Brazil.; Public Health Care Division, City of Ibirité, Brazil., Teixeira MM; Drug Research and Development Center, Federal University of Minas Gerais, Belo Horizonte, Brazil., Simplicio MIC; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil., Ribeiro LB; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil., Oliveira R; Research Division, Cardresearch-Cardiologia Assistencial e de Pesquisa, Brazil., Mills EJ; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

Publikováno v: JAMA network open [JAMA Netw Open] 2021 Apr 01; Vol. 4 (4), pp. e216468. Date of Electronic Publication: 2021 Apr 01.