Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Guillermo de la Vega-Barranco"'
Autor:
Sara Rodríguez-Acebes, Rodrigo Martín-Rufo, Alejandro Fernández-Llorente, Guillermo de la Vega-Barranco, Pilar Oroz, Elena Martín-Doncel, Luis Ignacio Toledo, Juan Méndez, Emilio Lecona
The replication stress response is an essential pathway that deals with the lesions that halt the progression of DNA replication forks even during an unperturbed S phase. Basal activation of the ATR and CHK1 kinases prevents the premature firing of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8e1651c47ea54a8258b11bfc5f3b00
https://doi.org/10.1101/2022.07.25.501345
https://doi.org/10.1101/2022.07.25.501345
Publikováno v:
Seminars in celldevelopmental biology. 132
Every time a cell copies its DNA the genetic material is exposed to the acquisition of mutations and genomic alterations that corrupt the information passed on to daughter cells. A tight temporal regulation of DNA replication is necessary to ensure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b48dcdfee9959e313bea6d4dd3b1bec
https://pubmed.ncbi.nlm.nih.gov/35210137
https://pubmed.ncbi.nlm.nih.gov/35210137
Autor:
Emilio Lecona, Patricia Ubieto-Capella, André Franz, Domenic Pilger, Thorsten Hoppe, Antonio Galarreta, Fabian den Brave, Pablo Valledor, Guillermo de la Vega-Barranco, Alejandro Fernández-Llorente, Vanesa Lafarga, Oscar Fernandez-Capetillo
Publikováno v:
Cell Reports
Summary The AAA+ ATPase VCP regulates the extraction of SUMO and ubiquitin-modified DNA replication factors from chromatin. We have previously described that active DNA synthesis is associated with a SUMO-high/ubiquitin-low environment governed by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a291217615ce3cb75fbfeedec0a8f0a2
https://doi.org/10.1016/j.celrep.2021.109819
https://doi.org/10.1016/j.celrep.2021.109819