Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Guillermo de la Cueva-Méndez"'
Autor:
Mark A. Preston, María Garrido-Barros, Camino Bermejo-Rodríguez, Alice Turnbull, Guillermo de la Cueva-Méndez, Belén Pimentel
Although not evolved to function in eukaryotes, prokaryotic toxin Kid induces apoptosis in human cells, and this is avoided by co-expression of its neutralizing antitoxin, Kis. Inspired by the way Kid becomes active in bacterial cells we had previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3682ece37719434a35ccaf66ff40dc
Autor:
Manuel Cano, Rebeca Núñez-Lozano, Alberto Delgado-García, José Manuel Jiménez-Hoyuela, Guillermo de la Cueva-Méndez, Rocío Lumbreras, Verena González-Rodríguez
Publikováno v:
Nanoscale. 9:812-822
The development of superparamagnetic iron oxide nanoparticle (SPION)-based diagnostic and therapeutic nanosystems holds a promise of revolutionizing biomedicine, helping to solve important unmet clinical needs. Such potential will only be fulfilled i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4363dabf080b7aae51fae6197873d4c9
https://doi.org/10.1039/c6nr07462f
https://doi.org/10.1039/c6nr07462f
Publikováno v:
RSC Advances. 6:70374-70382
The fabrication of multifunctional nanostructures constitutes an interesting area of research. Here we used a simple fullerene–amine coupling chemistry to produce a photofunctional and antioxidant magnetic material composed of multiple C60 molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6e3d66b69cefafbe46f27f1b327106
https://doi.org/10.1039/c6ra14047e
https://doi.org/10.1039/c6ra14047e
Autor:
Mauricio E. Calvo, Rebeca Núñez-Lozano, Belén Pimentel, Hernán Míguez, Guillermo de la Cueva-Méndez, José R. Castro-Smirnov
Publikováno v:
Advanced Healthcare Materials
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Protection from solar radiation is commonly achieved through the use of UV organic absorbers, such as benzophenones or benzotriazoles, often combined with inorganic materials such as TiO2 or ZnO2, supplied in the form of submicron size particles.[1]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a5df1259646a370b792c29958459cd
https://doi.org/10.1002/adhm.201500223
https://doi.org/10.1002/adhm.201500223
Autor:
Juan A. Bernal, Mark A. Preston, Xindan Wang, David J. Sherratt, Camino Bermejo-Rodríguez, Radhika Nair, Chukwuma A. Agu, Guillermo de la Cueva-Méndez, Belén Pimentel
Publikováno v:
Proceedings of the National Academy of Sciences. 111:2734-2739
Worldwide dissemination of antibiotic resistance in bacteria is facilitated by plasmids that encode postsegregational killing (PSK) systems. These produce a stable toxin (T) and a labile antitoxin (A) conditioning cell survival to plasmid maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfa0bee3dec0cf13c76f27f07ba3d5b
https://doi.org/10.1073/pnas.1308241111
https://doi.org/10.1073/pnas.1308241111
Publikováno v:
EMBO reports. 8:458-464
Plasmids are units of extrachromosomal genetic inheritance found in all kingdoms of life. They replicate autonomously and undergo stable propagation in their hosts. Despite their small size, plasmid replication and gene expression constitute a metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83662eb77936dd1d33fa0aa5d0d37bf
https://doi.org/10.1038/sj.embor.7400957
https://doi.org/10.1038/sj.embor.7400957
Publikováno v:
Current opinion in biotechnology. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47879a78105d1a4ebff87e235ca08d6
https://pubmed.ncbi.nlm.nih.gov/26421602
https://pubmed.ncbi.nlm.nih.gov/26421602
Autor:
Guillermo de la Cueva-Méndez, Mark A. Preston, Alice Turnbull, Camino Bermejo-Rodríguez, Isabelle Dionne, Belén Pimentel
Publikováno v:
ACS synthetic biology. 5(7)
Prokaryotes express intracellular toxins that pass unnoticed to carrying cells until coexpressed antitoxin partners are degraded in response to stress. Although not evolved to function in eukaryotes, one of these toxins, Kid, induces apoptosis in mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affe70777402bf022e69b1dcf28f6b2f
https://pubmed.ncbi.nlm.nih.gov/26230535
https://pubmed.ncbi.nlm.nih.gov/26230535
Publikováno v:
Current opinion in biotechnology. 35
To be effective, anticancer agents must induce cell killing in a selective manner, something that is proving difficult to achieve. Drug delivery systems could help to solve problems associated with the lack of selectivity of classical chemotherapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3285be2a5c96c14471a3427fa1ea92c
https://pubmed.ncbi.nlm.nih.gov/26277646
https://pubmed.ncbi.nlm.nih.gov/26277646
Autor:
Anthony D. Mills, Guillermo de la Cueva-Méndez, Ramón Díaz-Orejas, Ronald A. Laskey, Lorena Clay-Farrace
Publikováno v:
The EMBO Journal. 22:246-251
Plasmid R1 inhibits growth of bacteria by synthesizing an inhibitor of cell proliferation, Kid, and a neutralizing antidote, Kis, which binds tightly to the toxin. Here we report that this toxin and antidote, which have evolved to function in bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9775f18a152d6ff3c7d2ccadfef9d79f
https://doi.org/10.1093/emboj/cdg026
https://doi.org/10.1093/emboj/cdg026