Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Guillermo Scicli"'
Autor:
Thaiz Ferraz Borin, Debora A P C Zuccari, Bruna V Jardim-Perassi, Lívia C Ferreira, A S M Iskander, Nadimpalli Ravi S Varma, Adarsh Shankar, Austin M Guo, Guillermo Scicli, Ali S Arbab
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116247 (2014)
A selective inhibitor of 20-HETE synthesis, HET0016, has been reported to inhibit angiogenesis. 20-HETE has been known as a second mitogenic messenger of angiogenesis inducing growth factors. HET0016 effects were analyzed on MDA-MB-231 derived breast
Externí odkaz:
https://doaj.org/article/0266ef7d2ad343b5be9f4c5917c8426a
Autor:
Chen, Ping, Scicli, Gloria M., Guo, Meng, Fenstermacher, Joseph D., Dahl, David, Edwards, Paul A., Guillermo Scicli, A.
Publikováno v:
In Experimental Eye Research 2006 83(5):1041-1051
Autor:
A. Guillermo Scicli, Krishna Rao Maddippati, Adnan R. Munkarah, Rouba Ali-Fehmi, Z. Al-Wahab, Xiuli Liu, Austin M. Guo
Publikováno v:
Cancer Chemotherapy and Pharmacology. 68:1273-1283
Eicosanoid-related enzymes have been implicated in the pathogenesis of various cancers. Little is known about the relevance of lipoxygenase pathway to ovarian cancer growth. In this study, we examined the role of 12-lipoxygenase (12-LOX), the main hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fed410ee3ed36d2a5c2c6f76e9615e5
https://doi.org/10.1007/s00280-011-1595-y
https://doi.org/10.1007/s00280-011-1595-y
Autor:
Austin M. Guo, John R. Falck, Ali S. Arbab, A. Guillermo Scicli, Norman L. Lehman, Ju Sheng, G Scicli, Paul A. Edwards, Richard J. Roman
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 327:10-19
Exogenous 20-hydroxyeicosatetraenoic acid (20-HETE) increases the growth of human glioma cells in vitro. However, glioma cells in culture show negligible 20-HETE synthesis. We examined whether inducing the expression of a 20-HETE synthase in a human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9c57cbf150987eac707bde2ff9f729
https://doi.org/10.1124/jpet.108.140889
https://doi.org/10.1124/jpet.108.140889
Autor:
Meng Guo, G Scicli, Ping Chen, Paul A. Edwards, A. Guillermo Scicli, Joseph D. Fenstermacher, David Dahl
Publikováno v:
Experimental Eye Research. 83:1041-1051
To study if the endogenous renin-angiotensin system affects diabetic retinal leukostasis, rats with streptozotocin-induced diabetes were treated with an ACE inhibitor (ramipril), an angiotensin II AT(1) receptor antagonist (losartan) and the Ca chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfc0ea9cc6f0c3a24d4eb7b804759a9
https://doi.org/10.1016/j.exer.2006.05.009
https://doi.org/10.1016/j.exer.2006.05.009
Publikováno v:
Microvascular Research. 63:304-315
The angiogenic vascular endothelial growth factor (VEGF) is believed to play a critical role in endothelial cell proliferation, differentiation, and sprouting. Small molecules that selectively inhibit the VEGF receptor-associated tyrosine kinase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84643f84b96a66596ceafd25b9ed5e27
https://doi.org/10.1006/mvre.2001.2383
https://doi.org/10.1006/mvre.2001.2383
Autor:
Austin M. Guo, Mohamed Saleh, Jing Yang, Michal L. Schwartzman, Rachel Ackerman, Ali S. Arbab, A. Guillermo Scicli, John R. Falck, Lawrence G Mendelowitz, Katherine H. Gotlinger, Michael Kessler, Li Chen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 348(3)
Circulating endothelial progenitor cells (EPC) contribute to postnatal neovascularization. We identified the cytochrome P450 4A/F–20-hydroxyeicosatetraenoic acid (CYP4A/F–20-HETE) system as a novel regulator of EPC functions associated with angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a2c12024daefb08fb2a8610552ed90
https://pubmed.ncbi.nlm.nih.gov/24403517
https://pubmed.ncbi.nlm.nih.gov/24403517
Publikováno v:
Japanese Journal of Pharmacology. 81:279-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f8556a7b11eaefeef2178adac5eff6
https://doi.org/10.1016/s0021-5198(19)30765-6
https://doi.org/10.1016/s0021-5198(19)30765-6
Publikováno v:
Journal of Vascular Surgery. 23:314-322
Purpose: Neointima formation after arterial injury is inhibited by increased blood flow. The object of this study was to determine whether nitric oxide mediates the effect of increased blood flow on neointima formation.Method: Balloon catheter denude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3a7f51e6e4d9db4e13647d52901551
https://doi.org/10.1016/s0741-5214(96)70276-8
https://doi.org/10.1016/s0741-5214(96)70276-8
Autor:
Li Chen, Alexander Braverman, Frank Zhang, John Falck, Ali Syed Arbab, Michal Schwartzman, A Guillermo Scicli, Austin M Guo
Publikováno v:
Hypertension. 60
The CYP4A-20-HETE system regulates the neovascularization process via its potent vascular effects mainly on endothelial cells and vascular smooth muscle cells. Endothelial progenitor cells (EPC) also actively participate in physiological and patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d478aac29a24ca5446c8df1d3d72348
https://doi.org/10.1161/hyp.60.suppl_1.a517
https://doi.org/10.1161/hyp.60.suppl_1.a517