Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guillermo Sanjuán"'
Autor:
Mónica García-Sevilla, Rafael Moreta-Martinez, David García-Mato, Gema Arenas de Frutos, Santiago Ochandiano, Carlos Navarro-Cuéllar, Guillermo Sanjuán de Moreta, Javier Pascau
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Adenoid Cystic Carcinoma is a rare and aggressive tumor representing less than 1% of head and neck cancers. This malignancy often arises from the minor salivary glands, being the palate its most common location. Surgical en-bloc resection with clear
Externí odkaz:
https://doaj.org/article/377abb61fdc7466386dee7c72d1e945c
Fcγ Receptor Deficiency Confers Protection Against Atherosclerosis in Apolipoprotein E Knockout Mice
Autor:
Julio Gallego-Delgado, Carmen Gomez-Guerrero, Purificación Hernández-Vargas, Alberto Lázaro, Oscar Lopez-Franco, Jesús Egido, Luis Angel Ortega, Virginia Lopez-Parra, Yusuke Suzuki, Guillermo Sanjuán, Guadalupe Ortiz-Muñoz
Publikováno v:
Circulation Research. 99:1188-1196
IgG Fc receptors (FcγRs) play a role in activating the immune system and in maintaining peripheral tolerance, but their role in atherosclerosis is unknown. We generated double-knockout (DKO) mice by crossing apolipoprotein E–deficient mice (apoE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6cbfd8e5a773674fb7495e0abac143
https://doi.org/10.1161/01.res.0000250556.07796.6c
https://doi.org/10.1161/01.res.0000250556.07796.6c
Autor:
Purificación Hernández-Vargas, Guillermo Sanjuán, Carmen Gomez-Guerrero, Guadalupe Ortiz-Muñoz, Yusuke Suzuki, Jesús Egido, Oscar Lopez-Franco, Julia Blanco
Publikováno v:
The Journal of Immunology. 172:6969-6977
Suppressors of cytokine signaling (SOCS) are cytokine-inducible proteins that modulate receptor signaling via tyrosine kinase pathways. We investigate the role of SOCS in renal disease, analyzing whether SOCS regulate IgG receptor (FcγR) signal path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f293cf7c78e63663e92a309ad5970
https://doi.org/10.4049/jimmunol.172.11.6969
https://doi.org/10.4049/jimmunol.172.11.6969
Autor:
Purificación Hernández-Vargas, Ko Okumura, Chisei Ra, Carmen Gomez-Guerrero, Yasuhiko Tomino, Isao Shirato, Yusuke Suzuki, Oscar Lopez-Franco, Guillermo Sanjuán, Alberto Lázaro, Jesús Egido, Julio Gallego-Delgado
Publikováno v:
The Journal of Immunology. 170:3243-3253
In immune complex (IC) diseases, FcR are essential molecules facilitating polymorphonuclear cell (PMN) recruitment and effector functions at the IC site. Although FcR-dependent initial tethering and FcR/integrin-dependent PMN accumulation were postul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614246f1c4066c57cd2c9f8e45309901
https://doi.org/10.4049/jimmunol.170.6.3243
https://doi.org/10.4049/jimmunol.170.6.3243
Autor:
Carmen Gomez-Guerrero, Oscar Lopez-Franco, Guillermo Sanjuán, Purificación Hernández-Vargas, Jesús Egido, Julia Blanco, Yusuke Suzuki
Publikováno v:
Kidney International. 62:2022-2034
Nitric oxide production in renal cells by immune complexes: Role of kinases and nuclear factor-κB. Background Interaction of deposited immune complexes (IC) with Fc receptors (FcR) on tissue cells elicits the release of inflammatory mediators leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089530609ba5380b586aa6fd3c685c01
https://doi.org/10.1046/j.1523-1755.2002.00653.x
https://doi.org/10.1046/j.1523-1755.2002.00653.x
Autor:
Yusuke Suzuki, Carmen Gomez-Guerrero, Jesús Egido, Isao Shirato, Purificación Hernández-Vargas, Ko Okumura, Marta Ruiz-Ortega, Oscar Lopez-Franco, Takeshi Sugaya, Chisei Ra, Yasuhiko Tomino, Guillermo Sanjuán
Publikováno v:
ResearcherID
FcR provides a critical link between ligands and effector cells in immune complex diseases. Emerging evidence reveals that angiotensin (Ang)II exerts a wide variety of cellular effects and contributes to the pathogenesis of inflammatory diseases. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f24672fca180562e4bbbabf2f8d267
https://doi.org/10.4049/jimmunol.169.8.4136
https://doi.org/10.4049/jimmunol.169.8.4136
Autor:
Carmen Gomez-Guerrero, Purificación Hernández-Vargas, Guillermo Sanjuán, Oscar Lopez-Franco, Yoshikage Yo, Jeffrey B. Kopp, Jesús Egido, Yusuke Suzuki, Julia Blanco
Publikováno v:
Scopus-Elsevier
Nuclear factor (NF)-kappa B regulates several genes implicated in the inflammatory response and represents an interesting therapeutic target. We examined the effects of gliotoxin (a fungal metabolite) and parthenolide (a plant extract), which possess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea297f50e81c63dfd9ca4896e1b50517
https://doi.org/10.1016/s0002-9440(10)64425-2
https://doi.org/10.1016/s0002-9440(10)64425-2
Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis
Autor:
Guillermo Sanjuán, Purificación Hernández-Vargas, Oscar Lopez-Franco, Yusuke Suzuki, Guadalupe Ortiz-Muñoz, Carmen Gomez-Guerrero, Jesús Egido, Luis Angel Ortega, Julia Ramírez Blanco
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 26(8)
Objective—Activation of transcription factor NF-κB is an important step in the development of vascular damage, because it controls inducible genes, including many inflammatory mediators. The pharmacological modulation of this process is the main o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a024ce33d9a33a2e589b81d864f7fa4
https://pubmed.ncbi.nlm.nih.gov/16741149
https://pubmed.ncbi.nlm.nih.gov/16741149
Autor:
Yusuke Suzuki, Carmen Gomez-Guerrero, Jesús Egido, Pablo Aguado-Roncero, Marta Ruiz-Ortega, Purificación Hernández-Vargas, Julia Ramírez Blanco, Oscar Lopez-Franco, Gloria Pérez-Tejerizo, Mónica Rupérez, Guadalupe Ortiz-Muñoz, Guillermo Sanjuán
Publikováno v:
Journal of the American Society of Nephrology : JASN. 16(6)
Suppressors of cytokine signaling (SOCS) family is constituted by cytokine-inducible proteins that modulate receptor signal transduction via tyrosine kinases, mainly the Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c6dcc6caf862f2618c3c8c9ea6b4e6
https://pubmed.ncbi.nlm.nih.gov/15829701
https://pubmed.ncbi.nlm.nih.gov/15829701
Autor:
Carmen Gomez-Guerrero, Oscar Lopez-Franco, Jesús Egido, Luis Ortega, Purificación Hernández-Vargas, G. Ortiz-Munoz, Guillermo Sanjuán
Publikováno v:
Atherosclerosis Supplements. 6:41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858467eaa538bba0c0c20c3644086ef6
https://doi.org/10.1016/s1567-5688(05)80162-x
https://doi.org/10.1016/s1567-5688(05)80162-x