Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Guillermo P. Vicent"'
Autor:
Paula Bujosa, Oscar Reina, Adrià Caballé, Anna Casas-Lamesa, Mònica Torras-Llort, Juan Pérez-Roldán, Ana Silvina Nacht, Guillermo P. Vicent, Jordi Bernués, Fernando Azorín
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114137- (2024)
Summary: Chromatin-associated RNAs (cRNAs) are a poorly characterized fraction of cellular RNAs that co-purify with chromatin. Their full complexity and the mechanisms regulating their packaging and chromatin association remain poorly understood. Her
Externí odkaz:
https://doaj.org/article/f614dbef4fd84e8cbf7f94063b1580af
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Steroid hormone receptors (SHRs) belong to a large family of ligand-activated nuclear receptors that share certain characteristics and possess others that make them unique. It was thought for many years that the specificity of hormone response lay in
Externí odkaz:
https://doaj.org/article/3e072baa4f1d4afba63ced42cbf0ad0b
Autor:
Amanda Garrido, Eunjeong Kim, Ana Teijeiro, Paula Sánchez Sánchez, Rosa Gallo, Ajay Nair, María Matamala Montoya, Cristian Perna, Guillermo P. Vicent, Javier Muñoz, Ramón Campos-Olivas, Johannes C. Melms, Benjamin Izar, Robert F. Schwabe, Nabil Djouder
Publikováno v:
J Hepatol
[Background & Aims]: Owing to the lack of genetic animal models that adequately recreate key clinical characteristics of cirrhosis, the molecular pathogenesis of cirrhosis has been poorly characterized, and treatments remain limited. Hence, we aimed
Autor:
Adali Pecci, Ana Silvina Nacht, Martin Stortz, Melisa Marini, Maria Florencia Ogara, Diego M. Presman, Valeria Levi, Guillermo P. Vicent, Santiago A. Rodríguez-Seguí
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nucleic Acids Research
instname
Nucleic Acids Research
The glucocorticoid and progesterone receptors (GR and PR) are closely related members of the steroid receptor family. Despite sharing similar structural and functional characteristics; the cognate hormones display very distinct physiological response
Autor:
Roberto Ferrari, Jofre Font-Mateu, Enrique Vidal, Antonios Lioutas, François Le Dily, José Carbonell, Roser Zaurin, Guillermo P. Vicent, Miguel Beato, Lara Isabel de Llobet Cucalon, Ana Silvina Nacht
Publikováno v:
Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
© The Author(s) 2021.
Here, we report that in T47D breast cancer cells 50 pM progestin is sufficient to activate cell cycle entry and the progesterone gene expression program. At this concentration, equivalent to the progesterone blood levels f
Here, we report that in T47D breast cancer cells 50 pM progestin is sufficient to activate cell cycle entry and the progesterone gene expression program. At this concentration, equivalent to the progesterone blood levels f
Autor:
María Ceballos-Chávez, Alicia Subtil-Rodríguez, Eugenia G Giannopoulou, Daniel Soronellas, Elena Vázquez-Chávez, Guillermo P Vicent, Olivier Elemento, Miguel Beato, José C Reyes
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005174 (2015)
While the importance of gene enhancers in transcriptional regulation is well established, the mechanisms and the protein factors that determine enhancers activity have only recently begun to be unravelled. Recent studies have shown that progesterone
Externí odkaz:
https://doaj.org/article/ad430184deb74b498410d8f06c959ef0
Autor:
A. Silvina Nacht, Enrique Vidal, Miguel Beato, Gaetano Verde, Guillermo P. Vicent, Roni H. G. Wright, Javier Quilez, Yasmina Cuartero, José Carbonell-Caballero, Lara I. De Llobet, François Le Dily, José Luis Villanueva-Cañas, Roberto Ferrari, Priyanka Sharma
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further describe that responsive TADs c
Autor:
Adali Pecci, Sol Yanel Nuñez, Luciana Rocha-Viegas, Guillermo P. Vicent, Maria Florencia Ogara, Verónica E. García, Joaquín Miguel Pellegrini, Micaela Silbermins
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Targeting the apoptosis machinery is a promising therapeutic approach in myeloid malignancies. BCL2L1 is a well-known glucocorticoid-responsive gene and a key apoptosis regulator that, when over-expressed, can contribute to tumor development, progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b046c24f91f274f3644dc9c11774f037
http://hdl.handle.net/10261/223065
http://hdl.handle.net/10261/223065
Autor:
Guillermo Pablo Vicent, Roser Zaurin, A Silvina Nacht, Ang Li, Jofre Font-Mateu, Francois Le Dily, Michiel Vermeulen, Matthias Mann, Miguel Beato
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000567 (2009)
Steroid hormones regulate gene expression by interaction of their receptors with hormone responsive elements (HREs) and recruitment of kinases, chromatin remodeling complexes, and coregulators to their target promoters. Here we show that in breast ca
Externí odkaz:
https://doaj.org/article/edd3270f4c154758af21f38bb32ebbdd
Autor:
Nicolás Bellora, Gabriela Alejandra Merino, Jara R, Enrique Vidal, Villanueva Jl, Guillermo P. Vicent, La Greca A, Miguel Beato, Elmer Andrés Fernández, Cristóbal Fresno, Rieschle It, Vallejo G, Javier Quilez Oliete, Le Dily F, Patricia Saragueta
Estrogen (E2) and Progesterone (Pg), via their specific receptors (ER and PR respectively), are major determinants in the development and progression of endometrial malignancies. Here, we have studied how E2 and the synthetic progestin R5020 affect g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9729fc759ac20d802efc653b3d4ada5
https://doi.org/10.1101/739466
https://doi.org/10.1101/739466