Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Guillermo Moya-Alvarado"'
Autor:
Guillermo Moya-Alvarado, Xavier Valero-Peña, Alejandro Aguirre-Soto, Fernando J. Bustos, Oscar M. Lazo, Francisca C. Bronfman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Brain-derived neurotrophic factor (BDNF) and its tropomyosin receptor kinase B (TrkB) are important signaling proteins that regulate dendritic growth and maintenance in the central nervous system (CNS). After binding of BDNF, TrkB is endocytosed into
Externí odkaz:
https://doaj.org/article/e38137c622b04ea38e1bba9c58359de0
Publikováno v:
Bio-Protocol, Vol 14, Iss 1 (2024)
Neurons are complex cells with two distinct compartments: the somatodendritic and the axonal domains. Because of their polarized morphology, it is challenging to study the differential cellular and molecular mechanisms that occur in axons and impact
Externí odkaz:
https://doaj.org/article/5a68ea952d6f47728a7ea5929c723247
Autor:
Guillermo Moya-Alvarado, Reynaldo Tiburcio-Felix, María Raquel Ibáñez, Alejandro A Aguirre-Soto, Miguel V Guerra, Chengbiao Wu, William C Mobley, Eran Perlson, Francisca C Bronfman
Publikováno v:
eLife, Vol 12 (2023)
Brain-derived neurotrophic factor (BDNF) and its receptors tropomyosin kinase receptor B (TrkB) and the p75 neurotrophin receptor (p75) are the primary regulators of dendritic growth in the CNS. After being bound by BDNF, TrkB and p75 are endocytosed
Externí odkaz:
https://doaj.org/article/37d3790d65424017bb673c13cb241a24
Autor:
Guillermo Moya-Alvarado, Miguel V. Guerra, Reynaldo Tiburcio, Evelyn Bravo, Francisca C. Bronfman
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105796- (2022)
Neurons are highly polarized cells that rely on the intracellular transport of organelles. This process is regulated by molecular motors such as dynein and kinesins and the Rab family of monomeric GTPases that together help move cargo along microtubu
Externí odkaz:
https://doaj.org/article/fc0a530947384d90bbe783b3601d7141
Autor:
Viviana Pérez, Francisca Bermedo-Garcia, Diego Zelada, Felipe A. Court, Miguel Ángel Pérez, Marco Fuenzalida, Johanna Ábrigo, Claudio Cabello-Verrugio, Guillermo Moya-Alvarado, Juan Carlos Tapia, Vicente Valenzuela, Claudio Hetz, Francisca C. Bronfman, Juan Pablo Henríquez
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase the expression of the p75NTR pan
Externí odkaz:
https://doaj.org/article/0b9402c28e954f8a8bcf73f82d244d49
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Neurotrophin receptors use endosomal pathways for signaling in neurons. However, how neurotrophins regulate the endosomal system for proper signaling is unknown. Rabs are monomeric GTPases that act as molecular switches to regulate membrane trafficki
Externí odkaz:
https://doaj.org/article/f739153b782e41ea860412d8092b49dd
Autor:
Guillermo Moya-Alvarado, Osvaldo Yañez, Nicole Morales, Angélica González-González, Carlos Areche, Marco Tulio Núñez, Angélica Fierro, Olimpo García-Beltrán
Publikováno v:
Molecules, Vol 26, Iss 9, p 2430 (2021)
Fourteen coumarin-derived compounds modified at the C3 carbon of coumarin with an α,β-unsaturated ketone were synthesized. These compounds may be designated as chalcocoumarins (3-cinnamoyl-2H-chromen-2-ones). Both chalcones and coumarins are recogn
Externí odkaz:
https://doaj.org/article/8f903effeb4b40edab5e349abb2857f4
Autor:
Guillermo Moya-Alvarado, Reynaldo Tiburcio-Felix, María Raquel Ibáñez, Alejandro A Aguirre-Soto, Miguel V Guerra, Chengbiao Wu, William C Mobley, Eran Perlson, Francisca C Bronfman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7a4733352c8495b88c05309bf3b4b1
https://doi.org/10.7554/elife.77455.sa2
https://doi.org/10.7554/elife.77455.sa2
Publikováno v:
Proceedings of the National Academy of Sciences. 120
In neurons, many membrane proteins, synthesized in cell bodies, must be efficiently delivered to axons to influence neuronal connectivity, synaptic communication, and repair. Previously, we found that axonal targeting of TrkA neurotrophin receptors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6219eacb4106f71098167bafc3df08
https://doi.org/10.1073/pnas.2205426120
https://doi.org/10.1073/pnas.2205426120
Autor:
Jerson González-Hernández, Guillermo Moya-Alvarado, Ana Lorena Alvarado-Gámez, Roberto Urcuyo, Miriam Barquero-Quirós, María Julia Arcos-Martínez
Publikováno v:
Mikrochimica acta. 189(12)
Fentanyl is a powerful synthetic opioid used to treat severe pain. New administration routes toward its illegal consumption for recreational purposes pose a growing threat to public health, either due to misuse or abuse of this substance. As a result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055ad93e91504920f8ceada111638bee
https://pubmed.ncbi.nlm.nih.gov/36446842
https://pubmed.ncbi.nlm.nih.gov/36446842