Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Guillermo Moscatelli"'
Autor:
Guillermo Moscatelli, Samanta Moroni, Juan Carlos Ramírez, Belén Warszatska, Lascano Fernanda, Nicolás González, Andrés Rabinovich, Jaime Altcheh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011895 (2024)
BackgroundIn regions with controlled vector transmission of T. cruzi, congenital transmission is the most frequent route of infection. Treatment with benznidazole (BZ) or nifurtimox (NF) for 60 days in girls and women of childbearing age showed to be
Externí odkaz:
https://doaj.org/article/a9356bbb1e534506abc964012e4bbd97
Autor:
Jaime Altcheh, Guillermo Moscatelli, Martin Caruso, Samanta Moroni, Margarita Bisio, Maria Rosa Miranda, Celia Monla, Maria Vaina, Maria Valdez, Lucrecia Moran, Teresa Ramirez, Oscar Ledesma Patiño, Adelina Riarte, Nicolas Gonzalez, Jayme Fernandes, Fabiana Alves, Isabela Ribeiro, Facundo Garcia-Bournissen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 5, p e0010850 (2023)
BackgroundThere is a major need for information on pharmacokinetics (PK) of benznidazole (BNZ) in children with Chagas disease (CD). We conducted a multicentre population PK, safety and efficacy study in children, infants and neonates with CD treated
Externí odkaz:
https://doaj.org/article/95dc14fa93374db69b2dd62bfebaad28
Autor:
Nicolás Leonel González, Guillermo Moscatelli, Samanta Moroni, Griselda Ballering, Laura Jurado, Nicolás Falk, Andrés Bochoeyer, Alejandro Goldsman, María Grippo, Héctor Freilij, Facundo Garcia Bournissen, Eric Chatelain, Jaime Altcheh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0010968 (2022)
BackgroundParasite persistence after acute infection with Trypanosoma cruzi is an important factor in the development of Chagas disease (CD) cardiomyopathy. Few studies have investigated the clinical effectiveness of CD treatment through the evaluati
Externí odkaz:
https://doaj.org/article/a55c1893c5f9412f8d54693685e06af6
Autor:
Jaime Altcheh, Luis Castro, Juan C Dib, Ulrike Grossmann, Erya Huang, Guillermo Moscatelli, Jimy José Pinto Rocha, Teresa Estela Ramírez, CHICO Study Group
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008912 (2021)
Nifurtimox is a recommended treatment for Chagas disease, but data from treated children are limited. We investigated the efficacy, safety and tolerability of nifurtimox administered as divisible, dispersible 30 mg and 120 mg tablets in children with
Externí odkaz:
https://doaj.org/article/1dcc32d8cefc4129bba991b7e817b145
Autor:
Luciana Noemí Garcia, Alejandra Destito Solján, Samanta Moroni, Nicolas Falk, Nicolás Gonzalez, Guillermo Moscatelli, Griselda Ballering, Facundo García Bournissen, Jaime M Altcheh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0009010 (2021)
In spite of being preventable, Congenital syphilis (CS) is still an important, and growing health problem worldwide. Fetal infection can be particularly aggressive, but newborns can be asymptomatic at birth and, if left untreated, develop systemic co
Externí odkaz:
https://doaj.org/article/70a921afa70b41678009f60f3018b403
Autor:
María Elena Marson, Facundo García Bournissen, Jaime Altcheh, Guillermo Moscatelli, Samantha Moroni, Guido Enrique Mastrantonio
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Chagas disease is a serious public health problem in Latin America and, due to migration, in other non-endemic regions. Benznidazole (BNZ) is first choice drug in pediatric therapeutics. However, little is known regarding its metabolism in humans. Th
Externí odkaz:
https://doaj.org/article/8091b8b184d7461f95a134d0e6016eb1
Autor:
Ana Catalina Blazquez, Ariel José Berenstein, Carolina Torres, Agustín Izquierdo, Carol Lezama, Guillermo Moscatelli, Elena Noemí De Matteo, Mario Alejandro Lorenzetti, María Victoria Preciado
Publikováno v:
Viruses, Vol 13, Iss 6, p 1172 (2021)
The sequence variability of the Epstein–Barr virus has been extensively studied throughout previous years in isolates from various geographic regions and consequent variations at both genetic and genomic levels have been described. However, isolate
Externí odkaz:
https://doaj.org/article/d343d0dd440741adafe7a2d1379c0241
Autor:
Guillermo Moscatelli, Samanta Moroni, Facundo García Bournissen, Nicolás González, Griselda Ballering, Alejandro Schijman, Ricardo Corral, Margarita Bisio, Héctor Freilij, Jaime Altcheh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007668 (2019)
BackgroundEvaluation of therapeutic response in chronic Chagas disease is a major challenge, due to prolonged persistence of Trypanosoma cruzi-specific antibodies, lack of sensitivity of parasitological tests, and need for long-term follow-up to obse
Externí odkaz:
https://doaj.org/article/18dd6ab6a8024ce0863873fbaa7a69cf
Autor:
Samanta Moroni, Maria Elena Marson, Guillermo Moscatelli, Guido Mastrantonio, Margarita Bisio, Nicolas Gonzalez, Griselda Ballering, Jaime Altcheh, Facundo García-Bournissen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007647 (2019)
BackgroundTreatment with nifurtimox (NF) for Chagas disease is discouraged during breast-feeding because no information on NF transfer into breast milk is available. NF is safe and effective for paediatric and adult Chagas disease. We evaluated the d
Externí odkaz:
https://doaj.org/article/f4c44df7b7214fd58cf7b61d5b9e843f
Autor:
Guillermo Moscatelli, Ada Berenstein, Ana Tarlovsky, Susana Siniawski, Miguel Biancardi, Griselda Ballering, Samanta Moroni, Marta Schwarcz, Susana Hernández, Facundo García-Bournissen, Andrés Espejo Cozzi, Héctor Freilij, Jaime Altcheh
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 5, Pp 644-648 (2015)
The primary objective of this study was to estimate the prevalence of this disease in women of childbearing age and children treated at health centres in underserviced areas of the city of Buenos Aires. Demographic and Chagas disease status data were
Externí odkaz:
https://doaj.org/article/12cd440af43f40cfac71ca8744099495