Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Guillermo M. Elias"'
Autor:
Arnold R. Kriegstein, Guillermo M. Elias, Laura A. B. Elias, Roger A. Nicoll, P. F. Apostolides
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20953-20958
The development of glutamatergic synapses involves changes in the number and type of receptors present at the postsynaptic density. To elucidate molecular mechanisms underlying these changes, we combine in utero electroporation of constructs that alt
Proteins of the PSD-95–like membrane-associated guanylate kinase (PSD-MAGUK) family are vital for trafficking AMPA receptors (AMPARs) to synapses, a process necessary for both basal synaptic transmission and forms of synaptic plasticity. Synapse-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e75a6c311ce8507246fc40e1133967e
https://europepmc.org/articles/PMC2840522/
https://europepmc.org/articles/PMC2840522/
Autor:
Roger A. Nicoll, Guillermo M. Elias
Publikováno v:
Trends in cell biology. 17(7)
Synaptic transmission underlies every aspect of brain function. Excitatory synapses, which release the neurotransmitter glutamate, are the most numerous type of synapse in the brain. The trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propi
Autor:
Hillel Adesnik, David S. Bredt, Siavash Karimzadegan, Susumu Tomita, Guillermo M. Elias, Roger A. Nicoll, Colin Kealey, Nathalie Rouach, Ronald S. Petralia, Keith Byrd
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2005, 8 (11), pp.1525-1533. ⟨10.1038/nn1551⟩
Nature Neuroscience, Nature Publishing Group, 2005, 8 (11), pp.1525-1533. ⟨10.1038/nn1551⟩
Synaptic plasticity involves activity-dependent trafficking of AMPA-type glutamate receptors. Numerous cytoplasmic scaffolding proteins are postulated to control AMPA receptor trafficking, but the detailed mechanisms remain unclear. Here, we show tha
Autor:
Valentin Stein, Seth G. N. Grant, Roger A. Nicoll, L. Funke, Guillermo M. Elias, David S. Bredt
Publikováno v:
International Journal of Developmental Neuroscience. 24:493-493
Publikováno v:
International Journal of Developmental Neuroscience. 24:520-520
Autor:
Roger A. Nicoll, David S. Bredt, Seth G. N. Grant, Guillermo M. Elias, Valentin Stein, Lars Funke
Publikováno v:
Neuron. (3):465
SummaryTrafficking of AMPA receptors (AMPA-Rs) to and from synapses controls the strength of excitatory synaptic transmission. However, proteins that cluster AMPA-Rs at synapses remain poorly understood. Here we show that PSD-95-like membrane-associa