Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Guillermo García-Cardeña"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The vascular endothelium is a multifunctional cellular system which directly influences blood components and cells within the vessel wall in a given tissue. Importantly, this cellular interface undergoes critical phenotypic changes in response to var
Externí odkaz:
https://doaj.org/article/ef3cca5466c24aa7ae58cdcb05c406b8
Autor:
Rebeccah J. Luu, B. Christopher Hoefler, Ashley L. Gard, Casey R. Ritenour, Miles T. Rogers, Ernest S. Kim, Jonathan R. Coppeta, Brian P. Cain, Brett C. Isenberg, Hesham Azizgolshani, Oscar R. Fajardo-Ramirez, Guillermo García-Cardeña, Matthew P. Lech, Lindsay Tomlinson, Joseph L. Charest, Corin Williams
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Tissue fibrosis is a major healthcare burden that affects various organs in the body for which no effective treatments exist. An underlying, emerging theme across organs and tissue types at early stages of fibrosis is the activation of pe
Externí odkaz:
https://doaj.org/article/8223c1e9f8d84ea8861ab8c9956e14d2
Autor:
Matthias Grass, Anthony D. McDougal, Adriana Blazeski, Roger D. Kamm, Guillermo García-Cardeña, C. Forbes Dewey
Publikováno v:
Journal of Biological Chemistry, 298 (5)
If a coronary blood vessel is occluded and the neighboring cardiomyocytes deprived of oxygen, subsequent reperfusion of the ischemic tissue can lead to oxidative damage due to excessive generation of reactive oxygen species. Car-diomyocytes and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ced21c3153ba41913b8670131efa0a
Autor:
Bipul R. Acharya, Dritan Agalliu, V.A. Alexandrescu, Zakaria Almuwaqqat, Rheure Alves-Lopes, Ken Arai, Wadih Arap, Victoria L. Bautch, Lisa M. Becker, Michelle P. Bendeck, Jan Walter Benjamins, Saptarshi Biswas, E. Boesmans, Livia L. Camargo, Peter Carmeliet, Munir Chaudhuri, Nicholas W. Chavkin, Ondine Cleaver, Clément Cochain, Michael S. Conte, Azzurra Cottarelli, Christie L. Crandall, Anne Cuypers, Andreas Daiber, Alan Dardik, Jui M. Dave, J.O. Defraigne, Wenjun Deng, Robert J. DeStefano, Devinder Dhindsa, Danny J. Eapen, Anne Eichmann, Christian El Amm, Omotayo Eluwole, Christian Faaborg-Andersen, Steven A. Fisher, Zorina S. Galis, Guillermo García-Cardeña, Xin Geng, Michael A. Gimbrone, Luis Gonzalez, Daniel M. Greif, Xiaowu Gu, Shuzhen Guo, Tara L. Haas, Omar Hahad, Pim van der Harst, Peter K. Henke, Karen K. Hirschi, C. Holemans, Gonçalo Hora de Carvalho, Song Hu, Jay D. Humphrey, Shabatun J. Islam, Xinguo Jiang, Luis Eduardo Juarez-Orozco, Angelos D. Karagiannis, Anita Kaw, Kaveeta Kaw, Fatemeh Kazemzadeh, A. Kerzmann, Alexander S. Kim, Ageliki Laina, Eva K. Lee, Jinyu Li, Wenlu Li, Chien-Jung Lin, Xiaolei Liu, Eng H. Lo, Josephine Lok, Mark W. Majesky, Ziad Mallat, Muzi J. Maseko, Dianna M. Milewicz, Amanda L. Mohabeer, Augusto C. Montezano, Giorgio Mottola, Thomas Münzel, Daniel D. Myers, Karla B. Neves, Mark R. Nicolls, MingMing Ning, Andrea T. Obi, Guillermo Oliver, Renata Pasqualini, Alessandra Pasut, Alexandra Pislaru, Aleksander S. Popel, Raymundo A. Quintana, Arshed A. Quyyumi, Francisco J. Rios, Stanley G. Rockson, Martina Rudnicki, Junichi Saito, Charles D. Searles, Timothy W. Secomb, Cristina M. Sena, Richard L. Sidman, Federico Silva-Palacios, Tracey L. Smith, Suman Sood, Laurence S. Sperling, R. Sathish Srinivasan, Kimon Stamatelopoulos, Konstantinos Stellos, Naidi Sun, Wen Tian, Rhian M. Touyz, Nikolaos Ι. Vlachogiannis, Jessica E. Wagenseil, Thomas W. Wakefield, Charlotte R. Wayne, Changhong Xing, Ming Wai Yeung, Yu Zhang, Chen Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368f68174074e2f57417a7dd878baa13
https://doi.org/10.1016/b978-0-12-822546-2.01002-9
https://doi.org/10.1016/b978-0-12-822546-2.01002-9
Autor:
Lindsey K. Stolze, Elamaran Meibalan, Juho Jalkanen, Minna U. Kaikkonen, Lei Hou, Pasi Tavi, Leandro Z. Agudelo, Tiit Örd, Manolis Kellis, Casey E. Romanoski, S. Linna-Kuosmanen, Jarmo Gunn, Anu Toropainen, Mantero Jc, Galani K, Guillermo García-Cardeña, Renfro A, Calum A. MacRae, E. Schmauch, Carles Boix, Ojanen J, Maija Hollmén, Tuomas Kiviniemi
Ischemic heart disease is the single most common cause of death worldwide with an annual death rate of over 9 million people. Genome-wide association studies have uncovered over 200 genetic loci underlying the disease, providing a deeper understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6cca2d8cc683661bf76311024e01800
https://doi.org/10.1101/2021.06.23.449672
https://doi.org/10.1101/2021.06.23.449672
Autor:
Teresa Peiseler, Ilias P. Doulamis, Guillermo García-Cardeña, Pedro J. del Nido, Juan M. Melero-Martin, Xuechong Hong, Ingeborg Friehs, Elamaran Meibalan, Nicholas A. Oh
Publikováno v:
Circulation. 142
Introduction: Endocardial Fibroelastosis (EFE) is a condition defined by the formation of fibrotic tissue on the endocardium, stunting cardiac development. The presence of EFE restricts diastolic compliance, leading to systolic and diastolic heart fa
Autor:
Carles Boix, Manolis Kellis, Suvi Linna Kuosmanen, Eloi Schmauch, Guillermo García-Cardeña, Jarmo Gunn, Yongjin Park, Tuomas Kiviniemi, Maija Hollmén, Galani K
Publikováno v:
Circulation. 142
Genome-wide association studies have uncovered over 200 genetic loci underlying coronary artery disease (CAD), providing great hope for a deeper understanding of the causal mechanisms leading to this disease. However, in order to understand CAD at th
Human endothelial cells (hECs) experience complex spatiotemporal hemodynamic flows and that directly regulate hEC function and susceptibility to cardiovascular disease. Recent medical imaging studies reveal that helical flows strongly correlate with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a14007c5b002573f464f92e41fa100
https://doi.org/10.1101/2020.08.28.268599
https://doi.org/10.1101/2020.08.28.268599
Autor:
Cheng Hock Toh, Niamh O’Regan, James S. O’Donnell, Joo Yeon Ko, George F. Murphy, Simon T. Abrams, Guozheng Wang, Alister Craig, Karl B. Seydel, Julien M.H. Toh, Michael J. Potchen, Terrie E. Taylor, Malcolm E. Molyneux, Christopher A. Moxon, Guillermo García-Cardeña, Sam Kampondeni, Janet Storm, Yasir Alhamdi, Steven Lane, Dagmara McGuinness
Publikováno v:
Blood advances
Blood Advances
Blood Adv
Blood Advances
Blood Adv
Microvascular thrombosis and blood–brain barrier (BBB) breakdown are key components of cerebral malaria (CM) pathogenesis in African children and are implicated in fatal brain swelling. How Plasmodium falciparum infection causes this endothelial di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11be61338e57c942124390c9351df7ab