Výsledky vyhledávání - "Guillermo Galdon"

Akademický článek

In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System

Autor: Guillermo Galdon, Nima Pourhabibi Zarandi, Nicholas A. Deebel, Sue Zhang, Olivia Cornett, Dmitry Lyalin, Mark J. Pettenati, YanHe Lue, Christina Wang, Ronald Swerdloff, Thomas D. Shupe, Colin Bishop, Kimberly Stogner, Stanley J. Kogan, Stuart Howards, Anthony Atala, Hooman Sadri-Ardekani

Publikováno v: Bioengineering, Vol 11, Iss 7, p 677 (2024)

Increasing survival rates of children following cancer treatment have resulted in a significant population of adult survivors with the common side effect of infertility. Additionally, the availability of genetic testing has identified Klinefelter syn

Externí odkaz: https://doaj.org/article/0d499f5a34b345c688140e6641678963

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Akademický článek

In vitro propagation of XXY human Klinefelter spermatogonial stem cells: A step towards new fertility opportunities

Autor: Guillermo Galdon, Nicholas A. Deebel, Nima Pourhabibi Zarandi, Darren Teramoto, YanHe Lue, Christina Wang, Ronald Swerdloff, Mark J. Pettenati, William G. Kearns, Stuart Howards, Stanley Kogan, Anthony Atala, Hooman Sadri-Ardekani

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Klinefelter Syndrome (KS) is characterized by a masculine phenotype, supernumerary sex chromosomes (47, XXY), and impaired fertility due to loss of spermatogonial stem cells (SSCs). Early testicular cryopreservation could be an option for future fert

Externí odkaz: https://doaj.org/article/dca5682826f54e5e814853440325de06

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In Vitro Propagation of XXY Undifferentiated Mouse Spermatogonia: Model for Fertility Preservation in Klinefelter Syndrome Patients

Autor: Guillermo Galdon, Nicholas A. Deebel, Nima Pourhabibi Zarandi, Mark J. Pettenati, Stanley Kogan, Christina Wang, Ronald S. Swerdloff, Anthony Atala, Yanhe Lue, Hooman Sadri-Ardekani

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 173, p 173 (2022)
International journal of molecular sciences, vol 23, iss 1
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 173
International Journal of Molecular Sciences

Klinefelter syndrome (KS) is characterized by a masculine phenotype, supernumerary sex chromosomes (usually XXY), and spermatogonial stem cell (SSC) loss in their early life. Affecting 1 out of every 650 males born, KS is the most common genetic caus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9aa18d979d6bdb096ddc06c16095403
https://www.mdpi.com/1422-0067/23/1/173

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Autor: Guillermo Galdon, Yanhe Lue, Stanley J. Kogan, Hooman Sadri-Ardekani, James Lovato, Anthony Atala, Kimberly Stogner-Underwood, Stuart Howards, Nicholas Deebel, Nima Pourhabibi Zarandi

Publikováno v: Human Reproduction Update. 26:58-72

BACKGROUND Klinefelter syndrome (KS) has been defined by sex chromosome aneuploidies (classically 47, XXY) in the male patient. The peripubertal timeframe in KS patients has been associated with the initiation of progressive testicular fibrosis, loss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f9e94bc96508e06f2928e735d8fc87
https://doi.org/10.1093/humupd/dmz038

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Cryostorage of immature and mature human testis tissue to preserve spermatogonial stem cells (SSCs): a systematic review of current experiences toward clinical applications

Autor: Hooman Sadri-Ardekani, Nima Pourhabibi Zarandi, Guillermo Galdon, Stanley J. Kogan, Anthony Atala

Publikováno v: Stem Cells and Cloning : Advances and Applications

While the survival rate of children with cancer is increasing, preserving fertility for prepubertal boys is still a challenge. Although intracytoplasmic sperm injection (ICSI) using frozen sperms has revolutionized infertility treatment, it is not ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf43fa9bf9f7d7f868708fe41e1d7f0
https://doi.org/10.2147/sccaa.s137873

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