Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Guillermo Fernández‐Varo"'
Autor:
Gregori Casals, María Antonieta Ballesteros, Angielys Zamora, Irene Martínez, Guillermo Fernández-Varo, Mireia Mora, Felicia A. Hanzu, Manuel Morales-Ruiz
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 558 (2024)
Introduction: Urine free cortisol measurements are routinely performed to evaluate hypercortisolism. Despite their analytical inaccuracy, immunoassay-based methods are frequently used. Advances in liquid chromatography–high-resolution mass spectrom
Externí odkaz:
https://doaj.org/article/db77746213f648adb534d31b3f7c5303
Autor:
Lena M. Ernst, Laura Mondragón, Joana Ramis, Muriel F. Gustà, Tetyana Yudina, Eudald Casals, Neus G. Bastús, Guillermo Fernández-Varo, Gregori Casals, Wladimiro Jiménez, Victor Puntes
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 765 (2023)
Nanoparticle (NP) pharmacokinetics significantly differ from traditional small molecule principles. From this emerges the need to create new tools and concepts to harness their full potential and avoid unnecessary risks. Nanoparticle pharmacokinetics
Externí odkaz:
https://doaj.org/article/7dd6ac6461cf496f97acc0d66699be14
Autor:
Bernat Córdoba-Jover, Altamira Arce-Cerezo, Jordi Ribera, Montse Pauta, Denise Oró, Gregori Casals, Guillermo Fernández-Varo, Eudald Casals, Victor Puntes, Wladimiro Jiménez, Manuel Morales-Ruiz
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background and aims Cerium oxide nanoparticles are effective scavengers of reactive oxygen species and have been proposed as a treatment for oxidative stress-related diseases. Consequently, we aimed to investigate the effect of these nanopar
Externí odkaz:
https://doaj.org/article/7f909eb33ae542cbac680be23ade6ce0
Autor:
María Rodríguez-García, Guillermo Fernández-Varo, Susana Hidalgo, Gabriela Rodríguez, Irene Martínez, Muling Zeng, Eudald Casals, Manuel Morales-Ruiz, Gregori Casals
Publikováno v:
Molecules, Vol 27, Iss 6, p 1889 (2022)
Circulating levels of 2-hydroxybutyrate (2HB) are highly related to glycemic status in different metabolomic studies. According to recent evidence, 2HB is an early biomarker of the future development of dysglycemia and type 2 diabetes mellitus and ma
Externí odkaz:
https://doaj.org/article/1c66cdfdb7c146ef82fffacb2b02fdba
Autor:
Gregori Casals, Meritxell Perramón, Eudald Casals, Irene Portolés, Guillermo Fernández-Varo, Manuel Morales-Ruiz, Victor Puntes, Wladimiro Jiménez
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 660 (2021)
Oxidative stress induced by the overproduction of free radicals or reactive oxygen species (ROS) has been considered as a key pathogenic mechanism contributing to the initiation and progression of injury in liver diseases. Consequently, during the la
Externí odkaz:
https://doaj.org/article/a863764e4bb84326bc259e4bc3311827
Autor:
Santiago Marfà, Josep Marti, Adalgiza Reyes, Gregori Casals, Guillermo Fernández-Varo, Silvia Carvajal, J.C. García-Valdecasas, Josep Fuster, Wladimiro Jiménez
Publikováno v:
Translational Oncology, Vol 9, Iss 5, Pp 445-452 (2016)
Colorectal cancer (CRC) is one of the most common cancers in the developed countries, and nearly 70% of patients with CRC develop colorectal liver metastases (CRLMs). During the last decades, several scores have been proposed to predict recurrence af
Externí odkaz:
https://doaj.org/article/80fd6d8650d545c78e317fbf9cd10ded
Autor:
Santiago Marfà, Manuel Morales-Ruiz, Denise Oró, Jordi Ribera, Guillermo Fernández-Varo, Wladimiro Jiménez
Publikováno v:
Biology Open, Vol 5, Iss 6, Pp 858-865 (2016)
At present, several procedures are used for staging liver fibrosis. However, these methods may involve clinical complications and/or present diagnostic uncertainty mainly in the early stages of the disease. Thus, this study was designed to unveil new
Externí odkaz:
https://doaj.org/article/ea2f4d2268bd497aa471ec8d4340e3ca
Autor:
Marina Parra-Robert, Eudald Casals, Nuria Massana, Muling Zeng, Meritxell Perramón, Guillermo Fernández-Varo, Manuel Morales-Ruiz, Víctor Puntes, Wladimiro Jiménez, Gregori Casals
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 425 (2019)
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic accumulation of lipids. Antisteatotic effects of cerium oxide nanoparticles (CeO2NPs) have recently been shown in animal models of liver disease. However, it is unclear whether the
Externí odkaz:
https://doaj.org/article/ff7d10e5cebc43b7ab039eb4c9e05653
Autor:
Gregori Casals, Guillermo Fernández-Varo, Pedro Melgar-Lesmes, Santi Marfà, Vedrana Reichenbach, Manuel Morales-Ruiz, Wladimiro Jiménez
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 5, Pp 1125-1136 (2013)
Background: The molecular mechanisms by which myocardial ischemia translates into ventricular remodeling remain unclear. Methods: We investigated whether hypoxia and proinflammatory cytokines are specific inducers of remodeling signals in an in vitro
Externí odkaz:
https://doaj.org/article/4cdc296f6baa476999f059fe264978f2
Autor:
Meritxell Perramón, Silvia Carvajal, Vedrana Reichenbach, Guillermo Fernández‐Varo, Loreto Boix, Laura Macias‐Muñoz, Pedro Melgar‐Lesmes, Jordi Bruix, Shlomo Melmed, Santiago Lamas, Wladimiro Jiménez
Publikováno v:
Liver International. 42:651-662
PTTG1 is almost undetectable in adult livers but is highly expressed in hepatocarcinoma. While little is known about its involvement in liver fibrosis, PTTG1 expression is associated with DLK1. We assessed the role of the PTTG1/DLK1 pathway in fibros