Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Guillermo Coronas-Samano"'
Autor:
Marta Olah, Vilas Menon, Naomi Habib, Mariko F. Taga, Yiyi Ma, Christina J. Yung, Maria Cimpean, Anthony Khairallah, Guillermo Coronas-Samano, Roman Sankowski, Dominic Grün, Alexandra A. Kroshilina, Danielle Dionne, Rani A. Sarkis, Garth R. Cosgrove, Jeffrey Helgager, Jeffrey A. Golden, Page B. Pennell, Marco Prinz, Jean Paul G. Vonsattel, Andrew F. Teich, Julie A. Schneider, David A. Bennett, Aviv Regev, Wassim Elyaman, Elizabeth M. Bradshaw, Philip L. De Jager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Imbalance of microglial phenotypes in the aging brain might underlie their involvement in late onset neurodegenerative diseases. Here we report the population structure of microglia in the aged human brain and the reduction of a particular microglia
Externí odkaz:
https://doaj.org/article/70f5aedb5f20425e97be8410947e4a81
Autor:
Joe C. Udeochu, Sadaf Amin, Yige Huang, Li Fan, Eileen Ruth S. Torres, Gillian K. Carling, Bangyan Liu, Hugo McGurran, Guillermo Coronas-Samano, Grant Kauwe, Gergey Alzaem Mousa, Man Ying Wong, Pearly Ye, Ravi Kumar Nagiri, Iris Lo, Julia Holtzman, Carlo Corona, Allan Yarahmady, Michael T. Gill, Ravikiran M. Raju, Sue-Ann Mok, Shiaoching Gong, Wenjie Luo, Mingrui Zhao, Tara E. Tracy, Rajiv R. Ratan, Li-Huei Tsai, Subhash C. Sinha, Li Gan
Publikováno v:
Nature Neuroscience. 26:737-750
Pathological hallmarks of Alzheimer’s disease (AD) precede clinical symptoms by years, indicating a period of cognitive resilience before the onset of dementia. Here, we report that activation of cyclic GMP–AMP synthase (cGAS) diminishes cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f63c16301d932a0b75e214f4703692
https://doi.org/10.1038/s41593-023-01315-6
https://doi.org/10.1038/s41593-023-01315-6
Autor:
Guillermo Coronas-Samano, Keeley L. Baker, Winston J. T. Tan, Alla V. Ivanova, Justus V Verhagen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Insufficient advances in the development of effective therapeutic treatments of sporadic Alzheimer's Disease (sAD) to date are largely due to the lack of sAD-relevant animal models. While the vast majority of models do recapitulate AD's hallmarks of
Externí odkaz:
https://doaj.org/article/367f32a1c4264523b5e3df5ec79cc302
Autor:
Jean Paul Vonsattel, David A. Bennett, Christina J. Yung, Naomi Habib, Julie A. Schneider, Mariko Taga, Marta Olah, Guillermo Coronas-Samano, Aviv Regev, Philip L. De Jager, Anthony Khairallah, Andrew F. Teich, Yiyi Ma, Vilas Menon
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92519c1ec4f03a961c5bd82f23aee961
https://doi.org/10.1002/alz.038589
https://doi.org/10.1002/alz.038589
Autor:
Andrew F. Teich, Danielle Dionne, Philip L. De Jager, Aviv Regev, Julie A. Schneider, Roman Sankowski, Jean Paul Vonsattel, Jeffrey Helgager, Jeffrey A. Golden, Marta Olah, Rani A. Sarkis, Dominic Grün, Vilas Menon, Wassim Elyaman, Naomi Habib, Elizabeth M. Bradshaw, Guillermo Coronas-Samano, Alexandra Kroshilina, Anthony Khairallah, Mariko Taga, David A. Bennett, Page B. Pennell, Christina J. Yung, Marco Prinz, Yiyi Ma, Garth Rees Cosgrove, Maria Cimpean
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The extent of microglial heterogeneity in humans remains a central yet poorly explored question in light of the development of therapies targeting this cell type. Here, we investigate the population structure of live microglia purified from human cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47464d4a3e1542de898c6586fe4b11ff
https://hdl.handle.net/21.11116/0000-0007-AAE0-C21.11116/0000-0007-85C5-4
https://hdl.handle.net/21.11116/0000-0007-AAE0-C21.11116/0000-0007-85C5-4
Autor:
Verhagen, Justus jverhagen@jbpierce.org
Publikováno v:
Chemosensory Perception. Aug2015, Vol. 8 Issue 2, p78-84. 7p.
Publikováno v:
Genomics & Genetics Weekly; 6/16/2023, p1253-1253, 1p
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease.
Autor:
Olah, Marta, Menon, Vilas, Habib, Naomi, Taga, Mariko F., Ma, Yiyi, Yung, Christina J., Cimpean, Maria, Khairallah, Anthony, Coronas-Samano, Guillermo, Sankowski, Roman, Grün, Dominic, Kroshilina, Alexandra A., Dionne, Danielle, Sarkis, Rani A., Cosgrove, Garth R., Helgager, Jeffrey, Golden, Jeffrey A., Pennell, Page B., Prinz, Marco, Vonsattel, Jean Paul G.
Publikováno v:
Nature Communications; 11/30/2020, Vol. 11 Issue 1, pN.PAG-N.PAG, 1p