Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Guillermo Carbajosa"'
Autor:
Alfonso Alba-Bernal, Ana Godoy-Ortiz, María Emilia Domínguez-Recio, Esperanza López-López, María Elena Quirós-Ortega, Victoria Sánchez-Martín, María Dunia Roldán-Díaz, Begoña Jiménez-Rodríguez, Jesús Peralta-Linero, Estefanía Bellagarza-García, Laura Troyano-Ramos, Guadalupe Garrido-Ruiz, M. Isabel Hierro-Martín, Luis Vicioso, Álvaro González-Ortiz, Noelia Linares-Valencia, Jesús Velasco-Suelto, Guillermo Carbajosa, Alicia Garrido-Aranda, Rocío Lavado-Valenzuela, Martina Álvarez, Javier Pascual, Iñaki Comino-Méndez, Emilio Alba
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Early breast cancer patients often experience relapse due to residual disease after treatment. Liquid biopsy is a methodology capable of detecting tumor components in blood, but low concentrations at early stages pose challenges. To detect t
Externí odkaz:
https://doaj.org/article/bd142254ea644db1a1eebb2a629ad70a
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background The human mitochondrial genome is transcribed as long strands of RNA containing multiple genes, which require post-transcriptional cleavage and processing to release functional gene products that play vital roles in cellular energ
Externí odkaz:
https://doaj.org/article/20e39d84257d490289daea76946d8afe
Autor:
Begoña Jiménez-Rodríguez, Alfonso Alba-Bernal, Esperanza López-López, María Elena Quirós-Ortega, Guillermo Carbajosa, Alicia Garrido-Aranda, Martina Álvarez, Ana Godoy-Ortiz, María Isabel Queipo-Ortuño, Luis Vicioso, Gema Díaz-Córdoba, María Dunia Roldán-Díaz, Jesús Velasco-Suelto, Cristina Hernando, Begoña Bermejo, Ana Julve-Parreño, Ana Lluch, Javier Pascual, Iñaki Comino-Méndez, Emilio Alba
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 146 (2022)
Breast cancer (BC) is the most prevalent cancer in women. While usually detected when localized, invasive procedures are still required for diagnosis. Herein, we developed a novel ultrasensitive pipeline to detect circulating tumor DNA (ctDNA) in a s
Externí odkaz:
https://doaj.org/article/2f67b0e0538a475fb2b1d161a6d6a0a9
Autor:
Aminah T Ali, Lena Boehme, Guillermo Carbajosa, Vlad C Seitan, Kerrin S Small, Alan Hodgkinson
Publikováno v:
eLife, Vol 8 (2019)
Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 t
Externí odkaz:
https://doaj.org/article/64a0a455fd144d8183425a122e994942
Autor:
Alfonso Alba-Bernal, Ana Godoy-Ortiz, María Emilia Domínguez-Recio, Begoña Jimenez-Rodriguez, María Elena Quirós-Ortega, Esperanza López-López, Guillermo Carbajosa-Antona, Jesús Peralta-Linero, Luis Vicioso, Estefanía Bellagarza-García, Guadalupe Dolores Garrido-Ruiz, Cynthia Robles-Podadera, Alicia Garrido-Aranda, María Dunia Roldán-Díaz, Jesús Velasco-Suelto, Rocío Lavado-Valenzuela, Martina Álvarez, Nuria Ribelles, Javier Pascual, Emilio Alba, Iñaki Comino-Méndez
Publikováno v:
Cancer Research. 83:6610-6610
Breast cancer (BC) is the most frequent neoplasia affecting women worldwide normally detected at early stages. In this regard, early diagnosis drastically decreases mortality, however, around 20% of these patients will later relapse. This is mainly c
Autor:
Michael J. O'Neill, David A. Collier, Alan Hodgkinson, Richard Dobson, Guillermo Carbajosa, Eva Wozniak, Hong Wang, Nathan Lawless, Angela Hodges, Stephen Newhouse, John W. Ryder, Kristie Wood, Karim Malki, Charles A. Mein
A microglia response to pathogenic signals in diseases such as Alzheimer’s disease (AD) has long been recognised, but recent genetic findings have cemented their direct causal contribution to AD and thus the potential to target them or their effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae8f3b1fabf1d01baebb27a64970fc96
https://doi.org/10.1101/2021.07.16.452732
https://doi.org/10.1101/2021.07.16.452732
Autor:
Vlad C. Seitan, Alan Hodgkinson, Kerrin S. Small, Lena Boehme, Guillermo Carbajosa, Aminah T. Ali
Publikováno v:
Ali, A T, Boehme, L, Carbajosa, G, Seitan, V C, Small, K S & Hodgkinson, A 2019, ' Nuclear Genetic Regulation of the Human Mitochondrial Transcriptome ', eLife, vol. 8, no. e41927, e41927, pp. 1-23 . https://doi.org/10.7554/eLife.41927
eLife, Vol 8 (2019)
eLife
eLife, Vol 8 (2019)
eLife
Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79319de55abbe32e08989baab391a775
https://kclpure.kcl.ac.uk/en/publications/60ac6a04-76ab-44d0-aeb4-6dc39ef8bdd9
https://kclpure.kcl.ac.uk/en/publications/60ac6a04-76ab-44d0-aeb4-6dc39ef8bdd9
Autor:
Guillermo Carbajosa, Nathan Lawless, Eva Wozniak, Karim Malki, Angela Hodges, Richard Dobson, Kristie Wood, Stephen Newhouse, Hong Wang, John W. Ryder, Michael J. O'Neill, David A. Collier, Charles A. Mein
Publikováno v:
Carbajosa, G, Malki, K, Lawless, N, Wang, H, Ryder, J W, Wozniak, E, Wood, K, Mein, C A, Dobson, R J B, Collier, D A, O'Neill, M J, Hodges, A K & Newhouse, S J 2018, ' Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain ', Neurobiology of Aging, vol. 69, pp. 151-166 . https://doi.org/10.1016/j.neurobiolaging.2018.04.019
Rare heterozygous coding variants in the Triggering Receptor Expressed in Myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified. We examined the transcriptional consequences of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ee80debee5a3d95c02ee277c9de126
https://kclpure.kcl.ac.uk/ws/files/101828997/Loss_of_Trem2_in_Carbajosa_2018_GOLD_VoR.pdf
https://kclpure.kcl.ac.uk/ws/files/101828997/Loss_of_Trem2_in_Carbajosa_2018_GOLD_VoR.pdf
Autor:
Guillermo, Carbajosa, Karim, Malki, Nathan, Lawless, Hong, Wang, John W, Ryder, Eva, Wozniak, Kristie, Wood, Charles A, Mein, Richard J B, Dobson, David A, Collier, Michael J, O'Neill, Angela K, Hodges, Stephen J, Newhouse
Publikováno v:
Neurobiology of Aging
Rare heterozygous coding variants in the triggering receptor expressed in myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified. We examined the transcriptional consequences of the