Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guillermo A. Yudowski"'
Autor:
Martine Behra, Lorena González-Sepúlveda, Gaurav K. Varshney, Roberto Rodriguez-Morales, Guillermo A. Yudowski, Luis Colón-Cruz, Agnes Acevedo-Canabal, Shawn M. Burgess
Publikováno v:
Cannabis and Cannabinoid Research
Background and Objectives: The cannabinoid receptor 2 (CB2) was previously implicated in brain functions, including complex behaviors. Here, we assessed the role of CB2 in selected swimming behaviors in zebrafish larvae and developed an in vivo upsca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490acc41610282ea1d164e7d07a5d64d
https://doi.org/10.1089/can.2018.0025
https://doi.org/10.1089/can.2018.0025
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53965 (2013)
Postsynatptic density protein (PSD-95) is a 95 kDa scaffolding protein that assembles signaling complexes at synapses. Over-expression of PSD-95 in primary hippocampal neurons selectively increases synaptic localization of AMPA receptors; however, mi
Externí odkaz:
https://doaj.org/article/cb0fdc4282714bdbb3186b1660ffe58a
Autor:
Robert W. Kensler, Alexis Santana-Cruz, Guillermo A. Yudowski, Bruno Marie, Aranza Torrado-Tapias, Luis Colón-Cruz, Shawn M. Burgess, Gaurav K. Varshney, Martine Behra, Juan A. Cantres-Velez, Roberto Rodriguez-Morales, Olivier Renaud
The role of the cannabinoid receptor 2 (CNR2) is still poorly described in sensory epithelia. We found strong cnr2 expression in hair cells (HCs) of the inner ear and the lateral line (LL), a superficial sensory structure in fish. Next, we demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693c74a9d2d94e94bcf819e0013caca5
https://doi.org/10.1101/2020.08.18.253120
https://doi.org/10.1101/2020.08.18.253120
Autor:
Thibaut R. Pardo-García, Guillermo A. Yudowski, Nadira Yusif-Rodriguez, Carmen S. Maldonado-Vlaar
Publikováno v:
Neurosci Lett
Rationale The functional role of the endocannabinoid system (ECS) and Transient Receptor Potential Vanilloid type-1 (TRPV1) within the Nucleus Accumbens shell (NAc shell) remains unknown. Preclinical studies in rodents have reported that the ECS modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f55d2a44fe84a5368daf2ddea6d92bf
https://pubmed.ncbi.nlm.nih.gov/32422166
https://pubmed.ncbi.nlm.nih.gov/32422166
Autor:
Yaliang Tang, Gabriel E. Mateo-Semidey, Caitlin E. Scott, Debra A. Kendall, Chang-jiang Qiao, Dai Lu, Guillermo A. Yudowski, Caitlin A. D. Jagla
Publikováno v:
Molecular Pharmacology. 95:1-10
Cannabinoid receptor 1 (CB(1)) is a G-protein–coupled receptor that is abundant in the central nervous system. It binds several compounds in its orthosteric site, including the endocannabinoids, arachidonoyl ethanolamide (anandamide) and 2-arachido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9d68dd13e4f20116400170238fa6b0
https://doi.org/10.1124/mol.118.112854
https://doi.org/10.1124/mol.118.112854
Autor:
Louis M. Luttrell, Carlos Nogueras-Ortiz, Diane Gesty-Palmer, Guillermo A. Yudowski, Mi-Hye Lee, Erik G. Strungs, Kathryn M. Appleton, Yuri K. Peterson
Publikováno v:
SSRN Electronic Journal.
While structurally distinct ligands can “bias” the efficiency with which G protein-coupled receptors (GPCRs) activate different downstream effectors, it is thought that the events downstream of a single effector are inseparable. We tested a panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49732cd9021bddef3bc6be7652f68caa
https://doi.org/10.2139/ssrn.3422428
https://doi.org/10.2139/ssrn.3422428
Publikováno v:
Molecular Pharmacology. 90:620-626
The cannabinoid 1 receptor (CB1R) is one of the most abundant G protein-coupled receptors (GPCRs) in the central nervous system, with key roles during neurotransmitter release and synaptic plasticity. Upon ligand activation, CB1Rs may signal in three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00acffcad67c9f4eb35984156e70324f
https://doi.org/10.1124/mol.116.104539
https://doi.org/10.1124/mol.116.104539
Autor:
Ken Mackie, Debra A. Kendall, Guillermo A. Yudowski, Carlos Nogueras-Ortiz, Imran N. Mungrue, Francheska Delgado-Peraza, Kwang H. Ahn
Publikováno v:
Molecular Pharmacology
Activation of G protein-coupled receptors results in multiple waves of signaling that are mediated by heterotrimeric G proteins and the scaffolding proteins β-arrestin 1/2. Ligands can elicit full or subsets of cellular responses, a concept defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64e8fb72cfb1c44fb82d5a5b4d34956
http://europepmc.org/articles/PMC4885504
http://europepmc.org/articles/PMC4885504
Autor:
Guillermo A. Yudowski, Gaurav K. Varshney, Luis Colón-Cruz, Agnes Acevedo-Canabal, Martine Behra
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40fdb51ffeacd62424175f8c93bbbc45
https://doi.org/10.1096/fasebj.2018.32.1_supplement.825.5
https://doi.org/10.1096/fasebj.2018.32.1_supplement.825.5
Autor:
Gaurav K. Varshney, Shawn M. Burgess, Guillermo A. Yudowski, Martine Behra, Agnes Acevedo, Luis Colón-Cruz, Keisy Bonano
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::184b0f6c6ff118d0d16e20092c861c23
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.14
https://doi.org/10.1096/fasebj.2018.32.1_supplement.782.14