Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Guillermo A. Morales"'
Autor:
Dhananjaya Pal, Kendra R. Vann, Shweta Joshi, Namood E. Sahar, Guillermo A. Morales, Dalia El-Gamal, Tatiana G. Kutateladze, Donald L. Durden
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102931- (2021)
Summary: Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin's lymphoma and one of the most challenging blood cancers to combat due to frequent relapse after treatment. Here, we developed the first-in-class BTK/PI3K/BRD4 axis inhibitor
Externí odkaz:
https://doaj.org/article/450b01e00a41494d8bf5e7a3d13c8b6e
Autor:
Patrick J. Ropp, Jacob O. Spiegel, Jennifer L. Walker, Harrison Green, Guillermo A. Morales, Katherine A. Milliken, John J. Ringe, Jacob D. Durrant
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract Computational techniques such as structure-based virtual screening require carefully prepared 3D models of potential small-molecule ligands. Though powerful, existing commercial programs for virtual-library preparation have restrictive and/o
Externí odkaz:
https://doaj.org/article/f0ffcaf375ed4762b1db353acca3ff86
Publikováno v:
Tribology Online, Vol 19, Iss 1, Pp 95-104 (2024)
Indentations in rolling bearings from particle contamination introduce surface damage because they disturb lubrication and produce stress concentrations. In this article, a methodology is proposed where non-failed bearings that have been running in t
Externí odkaz:
https://doaj.org/article/85fa5512043342ee88b41a6ac45c33ca
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 11, Pp o3110-o3110 (2011)
In the title compound, C13H18O3SSi, the SO3 group displays a partial rotational (ca 50°) disorder about the C—S bond, with relative proportions 0.7744 (13):0.2256 (13). This disorder also forces the propynyl CH2 group to be disordered.
Externí odkaz:
https://doaj.org/article/483828748728453e839eeba63e9b270d
Publikováno v:
Tribology Online, Vol 18, Iss 6, Pp 280-291 (2023)
A previously developed and validated model for the life of rolling/sliding heavily-loaded lubricated contacts, that separates surface and subsurface survival is now adapted to include the effect of material inhomogeneities and it is applied to the ca
Externí odkaz:
https://doaj.org/article/885dad21f0494280ad10b46703c2e736
Surface Life Modelling of Tribological Components – From Surface Roughness to Bearings and Gear Life
Publikováno v:
Tribology Online, Vol 18, Iss 6, Pp 255-267 (2023)
With stringent environmental regulations and tougher economic reasons, tribological components like rolling bearings and gears are constantly under scrutiny when it comes to energy efficiency and reliability. This has driven engineers towards the con
Externí odkaz:
https://doaj.org/article/ce2d075c81164adb9f266fa4a767f259
Publikováno v:
Revista Colombiana de Cardiología, Vol 31, Iss 1 (2024)
Introducción: La hipertensión arterial resistente (HTAR) es definida como la presión arterial (PA) que se mantiene por encima de la meta, en pacientes en los que se ha confirmado la toma de tres o más antihipertensivos. Existe variabilidad en la
Externí odkaz:
https://doaj.org/article/47b5eab1e56e4f5d9689b15db1cc037b
Publikováno v:
Tribology Online, Vol 17, Iss 3, Pp 196-206 (2022)
In the modelling and characterization of changes undergone by engineering surfaces from tribological processes, an automatic detection system is often required to minimize subjective elements of the assessment in the analysis. Microgeometry changes i
Externí odkaz:
https://doaj.org/article/9be625f98b964114859e27883879c4d6
Autor:
Edgar Guillermo Méndez Morales, Horacio León Velasco, José Luis Gutiérrez Hernández, Efrén Díaz Aparicio, Oscar León Velasco
Publikováno v:
ESPACIO I+D: Innovación más Desarrollo, Vol 11, Iss 31 (2023)
El objetivo de este estudio es conocer la situación epidemiológica de la paratuberculosis bovina y determinar las prácticas de manejo que favorecen la presencia de esta enfermedad, en tres regiones económicas de mayor importancia ganadera en el e
Externí odkaz:
https://doaj.org/article/5b19e88c58464c50955fa49e12181852
Autor:
Guillermo Arana-Morales
Publikováno v:
Revista Colombiana de Cardiología, Vol 30, Iss 2, Pp 139-140 (2023)
Dear Editor, I was interested to read the article by Cadavid-Zuluaga et al.1 titled “Epidemiology of atrial fibrillation in a quaternary care clinic.
Externí odkaz:
https://doaj.org/article/0054edf0604445ed87daddc61745e533