Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Guillermo, Quintás"'
Autor:
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116813- (2024)
Externí odkaz:
https://doaj.org/article/1a45ac20be3b45a6bda044ba4b82f287
Autor:
Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116530- (2024)
Background: Serum transaminases, alkaline phosphatase and bilirubin are common parameters used for DILI diagnosis, classification, and prognosis. However, the relevance of clinical examination, histopathology and drug chemical properties have not bee
Externí odkaz:
https://doaj.org/article/20e9ebab41b6441c9e6177f4b5f66479
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3003 (2024)
Drug-induced liver injury (DILI) is a serious adverse hepatic event presenting diagnostic and prognostic challenges. The clinical categorization of DILI into hepatocellular, cholestatic, or mixed phenotype is based on serum alanine aminotransferase (
Externí odkaz:
https://doaj.org/article/66f829bb90be46c9af7a010df82a943d
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Drug hepatotoxicity assessment is a relevant issue both in the course of drug development as well as in the post marketing phase. The use of human relevant in vitro models in combination with powerful analytical methods (metabolomic analysis) is a pr
Externí odkaz:
https://doaj.org/article/9edcedea08d04a0ba85d5c79e9afb9c5
Autor:
Álvaro Pérez-Rubio, Polina Soluyanova, Erika Moro, Guillermo Quintás, Iván Rienda, María Dolores Periañez, Andrés Painel, José Vizuete, Judith Pérez-Rojas, José V. Castell, Ramón Trullenque-Juan, Eugenia Pareja, Ramiro Jover
Publikováno v:
Nutrients, Vol 15, Iss 14, p 3187 (2023)
Bariatric surgery (BS) has several benefits, including resolution of non-alcoholic fatty liver disease (NAFLD) in many patients. However, a significant percentage of patients do not experience improvement in fatty liver after BS, and more than 10% de
Externí odkaz:
https://doaj.org/article/a170d0eaefee49e2953c33f3d1091aed
Autor:
Marta Moreno-Torres, Guillem García-Llorens, Erika Moro, Rebeca Méndez, Guillermo Quintás, José Vicente Castell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) is a global strategy and regulation policy of the EU that aims to improve the protection of human health and the environment through the better and earlier identifi
Externí odkaz:
https://doaj.org/article/4dee4ab973534549828fbc123ace29d7
Autor:
Gil Rodas, Eva Ferrer, Xavier Reche, Juan Daniel Sanjuan-Herráez, Alan McCall, Guillermo Quintás
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Professional athletes undertake a variety of training programs to enhance their physical performance, technical-tactical skills, while protecting their health and well-being. Regular exercise induces widespread changes in the whole body in an extreme
Externí odkaz:
https://doaj.org/article/57d855a6e9b645dc9b4e2c8591ffc97b
Autor:
Isabel Ten-Doménech, Mari Merce Cascant-Vilaplana, Víctor Navarro-Esteve, Birgit Felderer, Alba Moreno-Giménez, Iván Rienda, María Gormaz, Marta Moreno-Torres, David Pérez-Guaita, Guillermo Quintás, Julia Kuligowski
Publikováno v:
Nutrients, Vol 15, Iss 5, p 1100 (2023)
Human milk (HM) is a complex biofluid containing a wide cell variety including epithelial cells and leukocytes. However, the cellular compositions and their phenotypic properties over the course of lactation are poorly understood. The aim of this pre
Externí odkaz:
https://doaj.org/article/a02edb0861f7409a8659931f4365f3a6
Autor:
Teresa Martínez-Sena, Erika Moro, Marta Moreno-Torres, Guillermo Quintás, Jan Hengstler, José V. Castell
Publikováno v:
Martínez-Sena, Teresa Moro, Erika Moreno Torres, Marta Quintás Soriano, Guillermo Hengstler, Jan G. Castell, José V. 2023 Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved Archives of Toxicology 97 1723 1738
Toxicity studies, among them hepatotoxicity, are key throughout preclinical stages of drug development to minimise undesired toxic effects that might eventually appear in the course of the clinical use of the new drug. Understanding the mechanism of
Autor:
Guillermo Quintás, Florian Caiment, Iván Rienda, Judith Pérez-Rojas, Eugenia Pareja, José V. Castell, Ramiro Jover
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9298 (2022)
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease worldwide, but a reliable non-invasive method to quantify liver steatosis in primary healthcare is not available. Circulating microRNAs have been proposed a
Externí odkaz:
https://doaj.org/article/697605491f3b42cba242a82d0d4e23e6