Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Guillermo, Gervasini"'
Autor:
Luz M. González, Nicolás R. Robles, Sonia Mota-Zamorano, José M. Valdivielso, Laura González-Rodríguez, Juan López-Gómez, Guillermo Gervasini
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in genes of the cyclooxygenase pathway (PTGS1, PTGS2, PTGES, PTGES2 and PTGES3) lead
Externí odkaz:
https://doaj.org/article/e2f9ee43073e4063a72b693a1ad151de
Autor:
Sonia Mota-Zamorano, Luz M. González, Nicolás R. Robles, José M. Valdivielso, José C. Arévalo-Lorido, Juan López-Gómez, Guillermo Gervasini
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 3039-3051 (2022)
Background Diabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk.Methods We screened 318 DN patients for 23 SNPs in four glucose transporters (SLC2A1, SLC2A2,
Externí odkaz:
https://doaj.org/article/fc02b76432544e2ba0cf5139d46a9c47
Autor:
Guillermo Gervasini, Zoraida Verde, Luz M. González, Celia Chicharro, Laura González-Rodríguez, Ana Fernández-Araque, Sonia Mota-Zamorano, Bárbara Cancho, Alberto Pérez-Hernández, Virginio García-López, Fernando Bandrés, Nicolás R. Robles
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2775 (2023)
There is a pressing need for more precise biomarkers of chronic kidney disease (CKD). Plasma samples from 820 subjects [231 with CKD, 325 with end-stage kidney disease (ESKD) and 264 controls] were analyzed by liquid chromatography with tandem mass s
Externí odkaz:
https://doaj.org/article/a10ba412ec1e4b49a47eae106484e3a9
Autor:
Guadalup García-Pino, Enrique Luna, Sonia Mota-Zamorano, Luz María González, María Ángeles Tormo, Guillermo Gervasini
Publikováno v:
Archives of Medical Science, Vol 20, Iss 4, Pp 1220-1227 (2021)
Introduction Leptin is a pro-inflammatory adipocytokine implicated in cardiovascular disease, insulin resistance, obesity and chronic kidney disease. Material and methods In a cohort of 236 renal transplant recipients, we aimed to determine whether
Externí odkaz:
https://doaj.org/article/0f9edd413c4b47a58e5afa2652d5d7a5
Autor:
Luz M. González, Nicolás R. Robles, Sonia Mota-Zamorano, José C. Arévalo-Lorido, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in
Externí odkaz:
https://doaj.org/article/519cba1a166442048c047e7931eb0d30
Autor:
Sonia Mota-Zamorano, Enrique Luna, Guadalupe Garcia-Pino, Luz M. González, Guillermo Gervasini
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 25, Iss , Pp 100648- (2020)
Background: We aimed to examine whether combined donor/recipient variants in the leptin receptor (LEPR) and adiponectin (ADIPOQ) genes may affect outcomes in renal transplantation. Methods: A total of 233 donors and their corresponding 307 recipients
Externí odkaz:
https://doaj.org/article/532a6af086594b8c940d6c781677988c
Autor:
Sonia Mota-Zamorano, Luz M González, Enrique Luna, José J Fernández, Áurea Gómez, Alberto Nieto-Fernández, Nicolás R Robles, Guillermo Gervasini
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224129 (2019)
Cytochrome P450 (CYP) enzymes metabolize arachidonic acid to vasoactive eicosanoids such as epoxyeicosatrienoic acids (EETs) and 20-Hydroxyeicosatetraenoic acid (20-HETE), whilst soluble epoxide hydrolase, encoded by the EPHX2 gene, is in charge of E
Externí odkaz:
https://doaj.org/article/7201841d15264311ab68a2895990ca5c
Autor:
Guadalupe Garcia-Pino, Enrique Luna, Lourdes Blanco, María Ángeles Tormo, Sonia Mota-Zamorano, Luz M González, Lilia Azevedo, Nicolás R Robles, Guillermo Gervasini
Publikováno v:
Progress in Transplantation. 32:112-119
Introduction: Body fat distribution is known to contribute to a variety of pathologies. Research Questions: We aimed to assess whether this distribution is associated with clinical outcomes in renal transplant recipients (RTR) and to examine its rela
Autor:
David Albuquerque, Luz M. González, Sonia Mota-Zamorano, Isalud Flores, Guillermo Gervasini, Angustias García-Herráiz
Publikováno v:
Acta Neuropsychiatrica. 33:307-316
The objective is to determine whether variability in the MSRA gene, related to obesity and several psychiatric conditions, may be relevant for psychopathological symptoms common in Anorexia Nervosa (AN) and/or for the susceptibility to the disorder.
Autor:
Rosa Diaz Campillejo, Guillermo Gervasini, J. Villa, Nicolás Roberto Robles, Elena Garcia de Vinuesa, Julian Valladares
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 19:93-97
Background and Aims: Anemia is a common complication of heart failure and Chronic Kidney Disease (CKD). Sacubitril-valsartan is a novel therapy for the treatment of chronic Heart Failure with a reduced Ejection Fraction (HFrEF). We have evaluated the