Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Guillermina, Hernando"'
Autor:
Guillermina Hernando, Cecilia Bouzat
Publikováno v:
MethodsX, Vol 12, Iss , Pp 102743- (2024)
The Caenorhabditis elegans egg hatching methodology is a valuable tool for assessing the anthelmintic activity of drugs and compounds and evaluating anthelmintic drug efficacy.Isolated eggs from gravid adults are exposed to different concentrations o
Externí odkaz:
https://doaj.org/article/5d6875fff40c4857820390d541ebe63d
Autor:
Juan Facundo Chrestia, Ornella Turani, Noelia Rodriguez Araujo, Guillermina Hernando, María del Carmen Esandi, Cecilia Bouzat
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106712- (2023)
Nicotinic acetylcholine receptors (nAChRs) comprise a family of pentameric ligand-gated ion channels widely distributed in the central and peripheric nervous system and in non-neuronal cells. nAChRs are involved in chemical synapses and are key actor
Externí odkaz:
https://doaj.org/article/d9e5850d5c9146e283245a748508cdea
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007895 (2019)
The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to develop novel compounds, among w
Externí odkaz:
https://doaj.org/article/17bd232ac0ca45139f75f815ae3132a5
Publikováno v:
The Journal of biological chemistry. 298(9)
Anthelmintics are used to treat human and veterinary parasitic diseases and to reduce crop and livestock production loss associated with parasitosis. The free-living nematode Caenorhabditis elegans, a model system for anthelmintic drug discovery, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b912d99f027505081972999977cff02c
https://pubmed.ncbi.nlm.nih.gov/35952761
https://pubmed.ncbi.nlm.nih.gov/35952761
Autor:
Guillermina Hernando, Cecilia Bouzat
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95072 (2014)
The prevalence of human and animal helminth infections remains staggeringly high, thus urging the need for concerted efforts towards this area of research. GABA receptors, encoded by the unc-49 gene, mediate body muscle inhibition in Caenorhabditis e
Externí odkaz:
https://doaj.org/article/54ced9e499bd4245a48ad07960798ffe
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007895 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Neglected Tropical Diseases
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Neglected Tropical Diseases
The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to develop novel compounds, among w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79acf4f8f272a437569f53e94ea88651
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007895
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007895
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in neuromuscular transmission. In nematodes, muscle nAChRs are targets of antiparasitic drugs. Bephenium is an anthelmintic compound whose molecular action in the free-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44d3d74ea1b4ac2fa3be70934ab952b
http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.118.113357
http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.118.113357
Publikováno v:
Molecular pharmacology. 94(5)
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in neuromuscular transmission. In nematodes, muscle nAChRs are targets of antiparasitic drugs. Bephenium is an anthelmintic compound whose molecular action in the free-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3070a59190ec817995011da370418762
https://pubmed.ncbi.nlm.nih.gov/30190363
https://pubmed.ncbi.nlm.nih.gov/30190363
Autor:
David B. Sattelle, Thomas P. R. Maynard, Diego Hernán Rayes, Steven D. Buckingham, Cecilia Bouzat, Guillermina Hernando, Rachel M. Jones, Andrew K. Jones, Adam Al-Diwani
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The nematode Caenorhabditis elegans is an established model organism for studying neurobiology. UNC-63 is a C. elegans nicotinic acetylcholine receptor (nAChR) α-subunit. It is an essential component of the levamisole-sensitive muscle nAChR (L-nAChR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965ea5e693bd512db110991e07068786
https://doi.org/10.1074/jbc.m110.177238
https://doi.org/10.1074/jbc.m110.177238
Autor:
Cecilia Bouzat, Guillermina Hernando
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95072 (2014)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
The prevalence of human and animal helminth infections remains staggeringly high, thus urging the need for concerted efforts towards this area of research. GABA receptors, encoded by the unc-49 gene, mediate body muscle inhibition in Caenorhabditis e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c94a7226cf71f4e0a7cb9de535d78f
http://europepmc.org/articles/PMC3990606?pdf=render
http://europepmc.org/articles/PMC3990606?pdf=render