Prevalence of HPV-DNA and E6 mRNA in lung cancer of HIV-infected patients

Autor: Guillem Sirera, Sebastián Videla, Verónica Saludes, Eva Castellà, Carolina Sanz, Aurelio Ariza, Bonaventura Clotet, Elisa Martró

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract HIV-infected individuals could be at a greater risk for developing lung cancer than the general population due to the higher prevalence in the former of human papillomavirus (HPV) in the oral cavity and higher smoking rates. Our aim was to a

Externí odkaz: https://doaj.org/article/6e4a4f8848ea447a9d9f97527de9b2b9

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Autor: Maria Pujantell, Eva Riveira-Muñoz, Roger Badia, Marc Castellví, Edurne Garcia-Vidal, Guillem Sirera, Teresa Puig, Cristina Ramirez, Bonaventura Clotet, José A. Esté, Ester Ballana

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

Abstract ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. H

Externí odkaz: https://doaj.org/article/b5349f651b58471ab2d3235a717d05d0

Gut Microbiota Linked to Sexual Preference and HIV Infection

Autor: Marc Noguera-Julian, Muntsa Rocafort, Yolanda Guillén, Javier Rivera, Maria Casadellà, Piotr Nowak, Falk Hildebrand, Georg Zeller, Mariona Parera, Rocío Bellido, Cristina Rodríguez, Jorge Carrillo, Beatriz Mothe, Josep Coll, Isabel Bravo, Carla Estany, Cristina Herrero, Jorge Saz, Guillem Sirera, Ariadna Torrela, Jordi Navarro, Manel Crespo, Christian Brander, Eugènia Negredo, Julià Blanco, Francisco Guarner, Maria Luz Calle, Peer Bork, Anders Sönnerborg, Bonaventura Clotet, Roger Paredes

Publikováno v: EBioMedicine, Vol 5, Iss C, Pp 135-146 (2016)

The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance followi

Externí odkaz: https://doaj.org/article/6faa3211ce75425d932a4c38e15aad48

Randomised study to assess the efficacy and safety of once-daily etravirine-based regimen as a switching strategy in HIV-infected patients receiving a protease inhibitor-containing regimen. Etraswitch study.

Autor: Patricia Echeverría, Anna Bonjoch, Jordi Puig, José Moltó, Roger Paredes, Guillem Sirera, Arelly Ornelas, Nuria Pérez-Álvarez, Bonaventura Clotet, Eugènia Negredo

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e84676 (2014)

Etravirine (ETR) was approved for patients with virological failure and antiretroviral resistance mutations. It has also shown antiviral efficacy in antiretroviral-naïve patients. However, data on the switching from protease inhibitors (PI) to ETR a

Externí odkaz: https://doaj.org/article/525c5840ddf34a9e8462bbe35847811e

Natural History of Anal Squamous Intraepithelial Lesions in HIV-Positive Men with Normal Baseline Cytology

Autor: Boris Revollo, Bonaventura Clotet, Javier Corral, David Parés, Guillem Sirera, Josep M. Llibre, Sebastián Videla, Francesc García-Cuyás

Publikováno v: AIDS Patient Care and STDs
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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The natural history of squamous intraepithelial lesions (SILs) in the anal canal of HIV-infected men is incompletely understood. We assessed the incidence and factors associated with SIL and invasive anal squamous cell carcinoma (IASCC) among HIV-inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750e783108e23ee0abe06138cd512f7e
https://pubmed.ncbi.nlm.nih.gov/31682165