Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Guillem R Esber"'
Publikováno v:
eLife, Vol 9 (2020)
Understanding how learned fear can be reduced is at the heart of treatments for anxiety disorders. Tremendous progress has been made in this regard through extinction training in which the aversive outcome is omitted. However, current progress almost
Externí odkaz:
https://doaj.org/article/ddaaf0efdfb243c6bd87f4f3ea1e7842
Autor:
Milena Rodriguez Alvarez, Hussam Alkaissi, Aja M. Rieger, Guillem R. Esber, Manuel E. Acosta, Stacy I. Stephenson, Allison V. Maurice, Laura Melissa Rodríguez Valencia, Christopher A. Roman, Juan Marcos Alarcon
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Stimulation of the inflammatory reflex (IR) is a promising strategy for treating systemic inflammatory disorders. Recent studies suggest oral sodium bicarbonate (NaHCO3) as a potential activator of the IR, offering a safe and cost-effective
Externí odkaz:
https://doaj.org/article/a7aa3dad064d4633a161cf47b53ed386
Autor:
Michael A McDannald, Guillem R Esber, Meredyth A Wegener, Heather M Wied, Tzu-Lan Liu, Thomas A Stalnaker, Joshua L Jones, Jason Trageser, Geoffrey Schoenbaum
Publikováno v:
eLife, Vol 3 (2014)
Externí odkaz:
https://doaj.org/article/20c20b2d994649ae86d9bf84fa414369
Autor:
Michael A McDannald, Guillem R Esber, Meredyth A Wegener, Heather M Wied, Tzu-Lan Liu, Thomas A Stalnaker, Joshua L Jones, Jason Trageser, Geoffrey Schoenbaum
Publikováno v:
eLife, Vol 3 (2014)
The orbitofrontal cortex (OFC) has been described as signaling outcome expectancies or value. Evidence for the latter comes from the studies showing that neural signals in the OFC correlate with value across features. Yet features can co-vary with va
Externí odkaz:
https://doaj.org/article/41fa0e0b0603405e92029c347ecc2fc4
Autor:
Mihwa Kang, Ingrid Reverte, Stephen Volz, Keith Kaufman, Salvatore Fevola, Anna Matarazzo, Fahd H. Alhazmi, Inmaculada Marquez, Mihaela D. Iordanova, Guillem R. Esber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract A fundamental assumption of learning theories is that the credit assigned to predictive cues is not simply determined by their probability of reinforcement, but by their ability to compete with other cues present during learning. This assump
Externí odkaz:
https://doaj.org/article/a8f18123b31a4fc3af1beadd2186a0c6
Autor:
Gabriel C. Loewinger, Inmaculada Márquez, Guillem R. Esber, Juan Carlos López, Estrella Díaz, Juan Pedro Vargas
Publikováno v:
Behavioral neuroscience. 136(4)
Surprising violations of outcome expectancies have long been known to enhance the associability of Pavlovian cues; that is, the rate at which the cue enters into further associations. The adaptive value of such enhancements resides in promoting new l
Publikováno v:
Psychopharmacology. 240:501-511
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
There are two forms of extinction learning, which are vital for adaptive behaviour: simple extinction, when an expected outcome fails to occur, and overexpectation, when an exaggerated expectation is in conflict with the actual outcome. Iordanova et
Externí odkaz:
https://doaj.org/article/e562431144b140c1a881c40e97d4e4f3
Autor:
Alexandra A. Usypchuk, Etienne JP Maes, Megan Lozzi, Matthew P.H. Gardner, Geoffrey Schoenbaum, Guillem R. Esber, Mihaela D. Iordanova
The discovery that DA transients can be mapped onto the reward prediction errors in temporal difference models is a pinnacle achievement of neuroscience. Yet, there is abundant evidence that DA activity reinforces actions, suggesting it serves as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::878c0639764eef29d734949977b9409f
https://doi.org/10.1101/2022.11.06.515338
https://doi.org/10.1101/2022.11.06.515338
Adaptive behaviour critically depends on the delicate and dynamic balance between acquisition and extinction memories. Disruption of this balance, particularly when the extinction memory loses control over behaviour, is the root of treatment failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78299cfe9b2ef71e6dd4899cfd3edea3
https://doi.org/10.1101/2022.03.02.481339
https://doi.org/10.1101/2022.03.02.481339